Shapes of Subcortical Structures in Adolescents With and Without Familial History of Substance Use Disorder

2020 ◽  
Author(s):  
Zhishun Wang ◽  
Diana V. Rodriguez Moreno ◽  
Yael M. Cycowicz ◽  
Lawrence V. Amsel ◽  
Keely Cheslack-Postava ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Subcortical Structures ◽  
Familial History ◽  
History Of

Shapes of Subcortical Structures in Adolescents With and Without Familial History of Substance Use Disorder

2020 ◽  
Author(s):  
Zhishun Wang ◽  
Diana V. Rodriguez Moreno ◽  
Yael M. Cycowicz ◽  
Lawrence V. Amsel ◽  
Keely Cheslack-Postava ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Subcortical Structures ◽  
Familial History ◽  
History Of

Temperament in schizophrenia: a study of the tridimensional personality questionnaire (TPQ)

2002 ◽  
Vol 17 (7) ◽  
pp. 379-383 ◽  
Author(s):  
Andrei Szöke ◽  
Franck Schürhoff ◽  
Nathalie Ferhadian ◽  
Frank Bellivier ◽  
Frédéric Rouillon ◽  
...  
Keyword(s):  
Substance Use ◽  
Multivariate Analysis ◽  
Psychiatric Disorder ◽  
Substance Use Disorder ◽  
Harm Avoidance ◽  
Personality Questionnaire ◽  
Familial History ◽  
French Version ◽  
Schizophrenic Patients ◽  
History Of

SummaryPurposeThe aim of this study was to assess dimensions of temperament as defined by Cloninger’s neurobiological model using the tridimensional personality questionnaire (TPQ) in a sample of consecutively recruited schizophrenic patients.Subjects and methodsWe used the French version of the TPQ to compare 45 stable, euthymic schizophrenic patients with 126 controls with no personal or familial history of psychiatric disorder. After comparison of TPQ scores between groups, we also performed a multivariate analysis to avoid the confounding effects of age, gender, and alcohol and substance use disorder comorbidity.ResultsHarm avoidance (HA) was higher in schizophrenic patients than in controls.Discussion and conclusionThis replicates and extends the results of previous studies suggesting that schizophrenic patients have high HA and that HA might be a marker for underlying genetic vulnerability to schizophrenia.

scholarly journals White matter integrity and functional connectivity in adolescents with a parental history of substance use disorder

2021 ◽  
Vol 1 (3) ◽  
pp. 100037
Author(s):  
Xiaofu He ◽  
Diana V. Rodriguez-Moreno ◽  
Yael M. Cycowicz ◽  
Keely Cheslack-Postava ◽  
Huilan Tang ◽  
...  
Keyword(s):  
Substance Use ◽  
White Matter ◽  
Functional Connectivity ◽  
Substance Use Disorder ◽  
White Matter Integrity ◽  
Parental History ◽  
History Of

scholarly journals Psychosocial and neural indicators of resilience among youth with a family history of substance use disorder

2018 ◽  
Vol 185 ◽  
pp. 198-206 ◽  
Author(s):  
Meghan E. Martz ◽  
Robert A. Zucker ◽  
John E. Schulenberg ◽  
Mary M. Heitzeg
Keyword(s):  
Substance Use ◽  
Family History ◽  
Substance Use Disorder ◽  
History Of

scholarly journals Correlates of prescription opioid therapy in Veterans with chronic pain and history of substance use disorder

2016 ◽  
Vol 53 (1) ◽  
pp. 25-36 ◽  
Author(s):  
Travis I. Lovejoy ◽  
Steven K. Dobscha ◽  
Dennis C. Turk ◽  
Melissa B. Weimer ◽  
Benjamin J. Morasco
Keyword(s):  
Chronic Pain ◽  
Substance Use ◽  
Substance Use Disorder ◽  
Opioid Therapy ◽  
Prescription Opioid ◽  
History Of

scholarly journals ADHD, Conduct Disorder, Substance Use Disorder, and Nonprescription Stimulant Use

2014 ◽  
Vol 21 (9) ◽  
pp. 776-782 ◽  
Author(s):  
Judith S. Brook ◽  
Elinor B. Balka ◽  
Chenshu Zhang ◽  
David W. Brook
Keyword(s):  
Substance Use ◽  
Conduct Disorder ◽  
Substance Use Disorder ◽  
Structural Equation ◽  
Equation Model ◽  
Community Based ◽  
Stimulant Use ◽  
History Of ◽  
Relationship Of ◽  
The Relationship

Objective: To assess whether the relationship of an ADHD diagnosis by adolescence to nonprescription stimulant use in adulthood is direct or indirect, via Conduct Disorder (CD) and/or Substance Use Disorder (SUD). Method: Data were obtained from multiple waves of interviews and questionnaires completed by 551 community-based participants when they were between the mean ages of 14.1 and 36.6 years. Results: The results of the structural equation model (SEM) supported both a direct association between early ADHD and later nonprescription stimulant use ( B = .18, z = 2.74) and the relationship from ADHD to later nonprescription stimulant use ( B = .01, z = 1.72) via CD and SUD. Conclusion: The longitudinal data supporting these paths suggest that efforts to prevent and treat the misuse of nonprescription stimulants may be more effective if attention is paid to those with a history of ADHD, as well as to those who also had CD and SUD.

scholarly journals Identifying factors associated with the discharge of male State patients from Weskoppies Hospital

2017 ◽  
Vol 23 ◽  
Author(s):  
Riaan G. Prinsloo ◽  
Andre Swanepoel ◽  
Gian Lippi
Keyword(s):  
Substance Abuse ◽  
Substance Use ◽  
Length Of Stay ◽  
Substance Use Disorder ◽  
Physical Aggression ◽  
Hospital Data ◽  
Related Factors ◽  
Term Care ◽  
Factors Associated ◽  
History Of

Background: Designated psychiatric facilities are responsible for the care, treatment and reintegration of State patients. The necessary long-term care places a considerable strain on health-care resources. Resource use should be optimised while managing the risks that patients pose to themselves and the community. Identifying unique factors associated with earlier discharge may decrease the length of stay. Factors associated with protracted inpatient care without discharge could identify patients who require early and urgent intervention.Aim: We identify socio-economic, demographic, psychiatric and charge-related factors associated with the discharge of male State patients.Methods: We reviewed the files of discharged and admitted forensic State patients at Weskoppies Psychiatric Hospital. Data were captured in an electronic recording sheet. The association between factors and the outcome measure (discharged vs. admitted) was determined using chi-squared tests and Fischer’s exact tests.Results: Discharged State patients were associated with being a primary caregiver (p = 0.031) having good insight into illness (p = 0.025) or offence (p = 0.005) and having had multiple successful leaves of absences. A lack of substance abuse during admission (p = 0.027), an absence of a diagnosis of substance use disorder (p = 0.013) and the absence of verbal and physical aggression (p = 0.002 and p = 0.016) were associated with being discharged. Prolonged total length of stay (9–12 years, p = 0.031) and prolonged length of stay in open wards (6–9 years, p = 0.000) were associated with being discharged. A history of previous offences (p = 0.022), a diagnosis of substance use disorder (p = 0.023), recent substance abuse (p = 0.018) and a history of physical aggression since admission (p = 0.017) were associated with continued admission.Conclusion: Discharge of State patients is associated with an absence of substance abuse, lack of aggression, multiple successful leave of absences and length of stay in hospital.

scholarly journals Clinical Audit of Gabapentin use in a Mental Health Hospital in Qatar

2018 ◽  
Author(s):  
Nervana Elbakary ◽  
Hazem Hashem
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Drug Users ◽  
Off Label ◽  
Wide Range ◽  
Potential Abuse ◽  
History Of ◽  
Almost All ◽  
To Receive ◽  
Mental Health Hospital

Bakground: Gabapentin was approved by FDA for the treatment of epilepsy, and as an analgesic for post-herpetic neuralgia (PHN). Gabapentin has been prescribed off-label for a wide range of disorders. Off-label use of gabapentin has been estimated to range from 83 to 95% of all its use. In the last few years, gabapentin has been becoming dispensed extensively for appropriate and inappropriate uses; meanwhile, drug-monitoring agencies have warned for potential abuse liabilities associated with gabapentin. The principal population at risk for addiction consists of patients with history of substance use disorders (SUD), mostly pregabalin and opioids. Purpose: To audit the appropriate use of gabapentin among a cohort of drug users, followed by subgroup analysis to determine the likelihood of drug abuse, misuse and/or diversion. Results: A total of 76 patients were included in the study. 99% of candidates used Gabapentin for off label indications, 30% for managing of behavioral symptoms related to dementia (BPSD). 27%, of the cohort used the medication had a confirmed history of substance-use disorder (SUD). One patient found to receive an inappropriate dose with regard to Creatine clearance Crcl. Conclusion: The data analysis has revealed that almost all gabapentin use in this setting was for off-label indications. Without placing limitations on the prescribing of this medication, it is expected that misuse of it by patients will continue to upsurge. This study highlights the need to standardize a hospital protocol for Gabapentin use within this facility, especially among patients with a history of substance- use disorder.

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