Behavioral Factors Mediated the Impact of Educational Attainment on Incident Heart Failure: A Mediation Analysis

2020 ◽  
Author(s):  
Yifen Lin ◽  
Shaozhao Zhang ◽  
Jianqiu Kong ◽  
Xiangbin Zhong ◽  
Yuqi Li ◽  
...  
Keyword(s):  
Heart Failure ◽  
Educational Attainment ◽  
Mediation Analysis ◽  
Behavioral Factors ◽  
Incident Heart Failure ◽  
The Impact

scholarly journals Relationship of Depressive Symptoms to the Impact of Physical Symptoms on Functional Status in Women With Heart Failure

2009 ◽  
Vol 18 (4) ◽  
pp. 348-356 ◽  
Author(s):  
Eun Kyeung Song ◽  
Debra K. Moser ◽  
Terry A. Lennie
Keyword(s):  
Heart Failure ◽  
Depressive Symptoms ◽  
Functional Status ◽  
Multiple Regression ◽  
Mediation Analysis ◽  
Physical Symptoms ◽  
Hierarchical Multiple Regression ◽  
Influence Functional ◽  
The Impact ◽  
The Relationship

Background Among patients with heart failure, women have worse functional status than do men, but little research has focused on determining factors that influence functional status in either sex. Objectives To compare factors that influence functional status in men and women with heart failure and to test whether depressive symptoms mediate the relationship between physical symptoms and functional status. Methods A cross-sectional, descriptive study design was used. A total of 231 patients, 133 men and 98 women, were recruited from an inpatient heart failure clinic in South Korea. Functional status (the Korean Activity Scale/Index), physical symptoms (the Symptom Status Questionnaire), depressive symptoms (the Beck Depression Inventory), and situational factors (living status, socioeconomic status) were measured. Hierarchical multiple regression and mediation analysis were used for data analysis. Results Women (mean score, 24.5; SD, 17.3) had worse functional status than did men (mean score, 31.9; SD, 20.1; P = .004). Dyspnea on exertion (β = −0.16), ankle swelling (β = −0.19), fatigue (β = −0.20), and depressive symptoms (β = −0.19) were independently associated with functional status in women, whereas only dyspnea on exertion (β = −0.30) influenced functional status of men in hierarchical multiple regression analysis. Mediation analysis indicated that depressive symptoms mediated the relationship between physical symptoms and functional status in women with heart failure, but not in men. Conclusions Distinct physical and psychological symptoms influence functional status in women with heart failure. A systematic multidimensional intervention may be required to target depressive symptoms to improve functional status in women with heart failure.

scholarly journals Atrial Fibrillation in Patients With Cardiomyopathy: Prevalence and Clinical Outcomes From Real‐World Data

2021 ◽  
Author(s):  
Benjamin J. R. Buckley ◽  
Stephanie L. Harrison ◽  
Dhiraj Gupta ◽  
Elnara Fazio‐Eynullayeva ◽  
Paula Underhill ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Clinical Outcomes ◽  
Restrictive Cardiomyopathy ◽  
The United States ◽  
Research Network ◽  
Real World Data ◽  
All Cause Mortality ◽  
Incident Heart Failure ◽  
The Impact

Background Cardiomyopathy is a common cause of atrial fibrillation (AF) and may also present as a complication of AF. However, there is a scarcity of evidence of clinical outcomes for people with cardiomyopathy and concomittant AF. The aim of the present study was therefore to characterize the prevalence of AF in major subtypes of cardiomyopathy and investigate the impact on important clinical outcomes. Methods and Results A retrospective cohort study was conducted using electronic medical records from a global federated health research network, with data primarily from the United States. The TriNetX network was searched on January 17, 2021, including records from 2002 to 2020, which included at least 1 year of follow‐up data. Patients were included based on a diagnosis of hypertrophic, dilated, or restrictive cardiomyopathy and concomitant AF. Patients with cardiomyopathy and AF were propensity‐score matched for age, sex, race, and comorbidities with patients who had a cardiomyopathy only. The outcomes were 1‐year mortality, hospitalization, incident heart failure, and incident stroke. Of 634 885 patients with cardiomyopathy, there were 14 675 (2.3%) patients with hypertrophic, 90 117 (7.0%) with restrictive, and 37 685 (5.9%) with dilated cardiomyopathy with concomitant AF. AF was associated with significantly higher odds of all‐cause mortality (odds ratio [95% CI]) for patients with hypertrophic (1.26 [1.13–1.40]) and dilated (1.36 [1.27–1.46]), but not restrictive (0.98 [0.94–1.02]), cardiomyopathy. Odds of hospitalization, incident heart failure, and incident stroke were significantly higher in all cardiomyopathy subtypes with concomitant AF. Among patients with AF, catheter ablation was associated with significantly lower odds of all‐cause mortality at 12 months across all cardiomyopathy subtypes. Conclusions Findings of the present study suggest AF may be highly prevalent in patients with cardiomyopathy and associated with worsened prognosis. Subsequent research is needed to determine the usefulness of screening and multisdisciplinary treatment of AF in this population.

What is the impact of depressive and anxious symptoms on quality of life in veterans with heart failure?

2010 ◽  
Author(s):  
J. A. Cully ◽  
L. L. Phillips ◽  
M. E. Kunik ◽  
M. A. Stanley ◽  
A. Deswal
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
The Impact
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