Opportunism in Vertical Contracting: A Dynamic Perspective

2020 ◽  
Author(s):  
Jihwan Do ◽  
Jeanine Miklós-Thal
Keyword(s):  
Dynamic Perspective ◽  
Vertical Contracting

Spirituality from a Psycho-dynamic Perspective

2019 ◽  
Vol 41 (2) ◽  
pp. 993-1016
Author(s):  
Sung Hyun Park
Keyword(s):  
Dynamic Perspective

The Relationship Between Income and Deprivation : A Dynamic Perspective.

1996 ◽  
Vol 47 (3) ◽  
pp. 709-717 ◽  
Author(s):  
Brian Nolan ◽  
Christopher T. Whelan
Keyword(s):  
Dynamic Perspective ◽  
The Relationship

NMR spectroscopy in the conformational analysis of peptides: an overview

2020 ◽  
Vol 27 ◽  
Author(s):  
Marian Vincenzi ◽  
Flavia Anna Mercurio ◽  
Marilisa Leone
Keyword(s):  
Nmr Spectroscopy ◽  
Protein Interactions ◽  
3D Structure ◽  
Theoretical Background ◽  
Triple Resonance ◽  
Protein Protein Interactions ◽  
Nmr Studies ◽  
Conformational Preferences ◽  
Dynamic Perspective ◽  
Nmr Methods

Background: NMR spectroscopy is one of the most powerful tools to study the structure and interaction properties of peptides and proteins from a dynamic perspective. Knowing the bioactive conformations of peptides is crucial in the drug discovery field to design more efficient analogue ligands and inhibitors of protein-protein interactions targeting therapeutically relevant systems. Objective: This review provides a toolkit to investigate peptide conformational properties by NMR. Methods: Articles cited herein, related to NMR studies of peptides and proteins were mainly searched through Pubmed and the web. More recent and old books on NMR spectroscopy written by eminent scientists in the field were consulted as well. Results: The review is mainly focused on NMR tools to gain the 3D structure of small unlabeled peptides. It is more application-oriented as it is beyond its goal to deliver a profound theoretical background. However, the basic principles of 2D homonuclear and heteronuclear experiments are briefly described. Protocols to obtain isotopically labeled peptides and principal triple resonance experiments needed to study them, are discussed as well. Conclusion: NMR is a leading technique in the study of conformational preferences of small flexible peptides whose structure can be often only described by an ensemble of conformations. Although NMR studies of peptides can be easily and fast performed by canonical protocols established a few decades ago, more recently we have assisted to tremendous improvements of NMR spectroscopy to investigate instead large systems and overcome its molecular weight limit.

scholarly journals The Biography of an Algorithm: Performing algorithmic technologies in organizations

2021 ◽  
Vol 2 (2) ◽  
pp. 263178772110046
Author(s):  
Vern L. Glaser ◽  
Neil Pollock ◽  
Luciana D’Adderio
Keyword(s):  
Decision Making ◽  
Organizational Capabilities ◽  
Negative Consequences ◽  
Organizational Decision Making ◽  
Computational Tools ◽  
Dynamic Perspective ◽  
Over Time

Algorithms are ubiquitous in modern organizations. Typically, researchers have viewed algorithms as self-contained computational tools that either magnify organizational capabilities or generate unintended negative consequences. To overcome this limited understanding of algorithms as stable entities, we propose two moves. The first entails building on a performative perspective to theorize algorithms as entangled, relational, emergent, and nested assemblages that use theories—and the sociomaterial networks they invoke—to automate decisions, enact roles and expertise, and perform calculations. The second move entails building on our dynamic perspective on algorithms to theorize how algorithms evolve as they move across contexts and over time. To this end, we introduce a biographical perspective on algorithms which traces their evolution by focusing on key “biographical moments.” We conclude by discussing how our performativity-inspired biographical perspective on algorithms can help management and organization scholars better understand organizational decision-making, the spread of technologies and their logics, and the dynamics of practices and routines.

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