Viral Kinetics of SARS-CoV-2 Over the Preclinical, Clinical and Postclinical Period

2020 ◽  
Author(s):  
Sukbin Jang ◽  
Ji-Young Rhee ◽  
Bo Kyeung Jung
Keyword(s):  
Viral Kinetics ◽  
Kinetics Of

scholarly journals Mathematical analysis of a within-host model of SARS-CoV-2

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Bhagya Jyoti Nath ◽  
Kaushik Dehingia ◽  
Vishnu Narayan Mishra ◽  
Yu-Ming Chu ◽  
Hemanta Kumar Sarmah
Keyword(s):  
Stability Analysis ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Basic Reproduction Ratio ◽  
Viral Kinetics ◽  
Reproduction Ratio ◽  
Biological Implication ◽  
Infection Models ◽  
Kinetics Of ◽  
The Basic Reproduction Number

AbstractIn this paper, we have mathematically analyzed a within-host model of SARS-CoV-2 which is used by Li et al. in the paper “The within-host viral kinetics of SARS-CoV-2” published in (Math. Biosci. Eng. 17(4):2853–2861, 2020). Important properties of the model, like nonnegativity of solutions and their boundedness, are established. Also, we have calculated the basic reproduction number which is an important parameter in the infection models. From stability analysis of the model, it is found that stability of the biologically feasible steady states are determined by the basic reproduction number $(\chi _{0})$ ( χ 0 ) . Numerical simulations are done in order to substantiate analytical results. A biological implication from this study is that a COVID-19 patient with less than one basic reproduction ratio can automatically recover from the infection.

scholarly journals Simulation Model for Dynamics of Dengue with Innate and Humoral Immune Responses

2018 ◽  
Vol 2018 ◽  
pp. 1-18 ◽  
Author(s):  
S. D. Perera ◽  
S. S. N. Perera
Keyword(s):  
Immune Response ◽  
Immune Responses ◽  
Dengue Virus ◽  
Dengue Infection ◽  
Asymptomatic Infection ◽  
Severe Dengue ◽  
Viral Kinetics ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
Kinetics Of

Dengue virus is a mosquito borne Flavivirus and the most prevalent arbovirus in tropical and subtropical regions around the world. The incidence of dengue has increased drastically over the last few years at an alarming rate. The clinical manifestation of dengue ranges from asymptomatic infection to severe dengue. Even though the viral kinetics of dengue infection is lacking, innate immune response and humoral immune response are thought to play a major role in controlling the virus count. Here, we developed a computer simulation mathematical model including both innate and adaptive immune responses to study the within-host dynamics of dengue virus infection. A sensitivity analysis was carried out to identify key parameters that would contribute towards severe dengue. A detailed stability analysis was carried out to identify relevant range of parameters that contributes to different outcomes of the infection. This study provides a qualitative understanding of the biological factors that can explain the viral kinetics during a dengue infection.

Early phase viral kinetics of chronic hepatitis C patients receiving telaprevir-based triple therapy: A comparison of two real-time PCR assays

2013 ◽  
Vol 99 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Eiichi Ogawa ◽  
Norihiro Furusyo ◽  
Masayuki Murata ◽  
Kazuhiro Toyoda ◽  
Kunimitsu Eiraku ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Triple Therapy ◽  
Chronic Hepatitis C ◽  
Real Time Pcr ◽  
Early Phase ◽  
Viral Kinetics ◽  
Pcr Assays ◽  
Kinetics Of ◽  
Chronic Hepatitis C Patients

scholarly journals Viral kinetics of SARS-CoV-2 in asymptomatic carriers and presymptomatic patients

2020 ◽  
Vol 95 ◽  
pp. 441-443 ◽  
Author(s):  
Seong Eun Kim ◽  
Hae Seong Jeong ◽  
Yohan Yu ◽  
Sung Un Shin ◽  
Soosung Kim ◽  
...  
Keyword(s):  
Viral Kinetics ◽  
Asymptomatic Carriers ◽  
Kinetics Of

scholarly journals Viral kinetics of SARS-CoV-2 over the preclinical, clinical, and postclinical period

2021 ◽  
Vol 102 ◽  
pp. 561-565
Author(s):  
Sukbin Jang ◽  
Ji-Young Rhee ◽  
Yu Mi Wi ◽  
Bo Kyeung Jung
Keyword(s):  
Viral Kinetics ◽  
Kinetics Of
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