scholarly journals Willingness to Pay for Morbidity and Mortality Risk-Reductions during An Epidemic. Theory and Preliminary Evidence from COVID-19

2020 ◽  
Author(s):  
Luciana Echazu ◽  
Diego Nocetti
2021 ◽  
Author(s):  
Diego A Sandoval ◽  
Inés Rama ◽  
María Quero ◽  
Miguel Hueso ◽  
Francisco Gómez ◽  
...  

Abstract Hemodialysis patients present more morbidity and mortality risk in coronavirus disease 2019. In patients who may develop severe symptoms the process called “viral sepsis” seems to be a crucial mechanism. In those cases, the hemodialysis procedure provides an excellent tool to explore the benefit of some extracorporeal therapies. We reported the outcome of 4 hemodialysis patients with severe COVID-19 treated with Seraph®100 hemoperfusion device. Three of four cases presented a good clinical response after hemoperfusion. In conclusion, the treatment with Seraph®100 device may be a simultaneous treatment to improve the hemodialysis patients with severe SARS-CoV-2.


Author(s):  
Anna Alberini ◽  
Maureen L. Cropper ◽  
Alan Krupnick ◽  
Nathalie B. Simon

2020 ◽  
Vol 15 ◽  
pp. 117727192091458
Author(s):  
Ashley N Edes ◽  
Katie L Edwards ◽  
Barbara A Wolfe ◽  
Janine L Brown ◽  
Douglas E Crews

Allostatic load, or the physiological dysregulation accumulated due to senescence and stress, is an established predictor of human morbidity and mortality and has been proposed as a tool for monitoring health and welfare in captive wildlife. It is estimated by combining biomarkers from multiple somatic systems into allostatic load indices (ALIs), providing a score representing overall physiological dysregulation. Such ALIs have been shown to predict disease and mortality risk in western lowland gorillas. In these prior analyses, we were unable to include lipid markers, a potential limitation as they are key biomarkers in human models. Recently, we were able to assay serum cholesterol and triglycerides and add them to our previous ALI. We then re-examined associations with health outcomes using binomial generalized linear models. We constructed ALIs using 2 pooling strategies and 2 methods. By itself, a 1-unit increase in allostatic load was associated with higher odds of all-cause morbidity and mortality, but results were mixed for cardiac disease. However, the best fit models for all-cause morbidity and cardiac disease included only age and sex. Allostatic load was retained alongside age in the best fit models for mortality, with a 1-unit increase associated with 23% to 45% higher odds of death. Compared with previous results, ALIs containing cholesterol and triglycerides better predict disease risk in zoo-housed western lowland gorillas, as evidenced by larger effect sizes for some models and better goodness of fit for all ALIs. Based on these results, we address methodology for future allostatic load research on wildlife.


2006 ◽  
Vol 21 (9) ◽  
pp. 2513-2520 ◽  
Author(s):  
Marlies Noordzij ◽  
Johanna C. Korevaar ◽  
Willem J. Bos ◽  
Elisabeth W. Boeschoten ◽  
Friedo W. Dekker ◽  
...  

1997 ◽  
Vol 64 (4) ◽  
pp. 1050-1058 ◽  
Author(s):  
Thomas L Higgins ◽  
Fawzy G Estafanous ◽  
Floyd D Loop ◽  
Gerald J Beck ◽  
Jar-Chi Lee ◽  
...  

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