Canakinumab for Treatment of Adult Onset Still's Disease to Achieve Reduction of Arthritic Manifestation (CONSIDER): A Phase 2, Multi-Centre, Placebo-Controlled Study

2019 ◽  
Author(s):  
Claudia Kedor ◽  
Joachim Listing ◽  
Jan Zernicke ◽  
Anja Weiß ◽  
Frank Behrens ◽  
...  
Keyword(s):  
Controlled Study ◽  
Adult Onset Still’S Disease ◽  
Phase 2 ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

scholarly journals Pulmonary artery hypertension prior to the relapse of adult‐onset Still's disease

2021 ◽  
Vol 9 (5) ◽  
Author(s):  
Yuki Hara ◽  
Takayoshi Morita ◽  
Katsunao Tanaka ◽  
Fusako Sera ◽  
Yasushi Sakata ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Artery Hypertension ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

scholarly journals Aseptic Meningitis and Cranial Nerve Palsy Revealing Adult‐Onset Still's Disease

1999 ◽  
Vol 29 (1) ◽  
pp. 220-221 ◽  
Author(s):  
I. Marie ◽  
H. Levesque ◽  
N. Perraudin ◽  
N. Cailleux ◽  
F. Lecomte ◽  
...  
Keyword(s):  
Aseptic Meningitis ◽  
Cranial Nerve ◽  
Cranial Nerve Palsy ◽  
Nerve Palsy ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

Markedly increased IL-18 liver expression in adult-onset Still's disease-related hepatitis

Rheumatology ◽  
2010 ◽  
Vol 50 (4) ◽  
pp. 776-780 ◽  
Author(s):  
R. Priori ◽  
F. Barone ◽  
C. Alessandri ◽  
S. Colafrancesco ◽  
I. B. McInnes ◽  
...  
Keyword(s):  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

THU0403 Scd163 in Adult Onset Still's Disease: A Biomarker for Macrophage Activation Related to Hyperferritinemia:

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 321.1-321
Author(s):  
S. Colafrancesco ◽  
R. Priori ◽  
E. Astorri ◽  
C. Perricone ◽  
N. Agmon-Levin ◽  
...  
Keyword(s):  
Macrophage Activation ◽  
Adult Onset Still’S Disease ◽  
Adult Onset ◽  
Still’S Disease ◽  
Still's Disease ◽  
Adult Onset Still's Disease

scholarly journals Adult onset Still’s disease in the elderly: a case-based literature review

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Arash Mollaeian ◽  
Jingjing Chen ◽  
Nina N. Chan ◽  
Gregory A. Nizialek ◽  
Christopher J. Haas
Keyword(s):  
Delayed Diagnosis ◽  
The Elderly ◽  
Adult Onset Still’S Disease ◽  
Inflammatory Disorder ◽  
Adult Onset ◽  
Still’S Disease ◽  
Diagnosis And Management ◽  
Still's Disease ◽  
Area Of Interest ◽  
Adult Onset Still's Disease

Abstract Background Adult onset Still’s disease (AOSD) is a rare inflammatory disorder that classically presents with high spiking fevers, evanescent rash, and arthritis. The diagnosis is one of exclusion and can be further complicated by atypical presentations, particularly in elderly patients in whom AOSD is very rare. Case presentation A case of AOSD in a 73-year-old woman with a non-classic presentation, leading to delayed diagnosis and management, is presented along with a review of the English literature for AOSD cases in elderly people over 70 years of age. Thirty nine case reports and series were identified and the current case was added, totaling 42 individual cases. Significant findings included a four-times higher prevalence in females, a higher prevalence of macrophage activation syndrome despite lower mortality, the presence of pruritic rash in almost one fifth of the cases, and high prevalence of delayed diagnosis. Conclusions AOSD in the elderly may vary from the classic criteria described in the medical literature and may lead to delayed diagnosis and management. Further evaluation and better characterization of AOSD in the elderly remains an area of interest.

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