Global, Regional, and National Cancer Death and Disability-Adjusted Life-Years (DALYs) for Cardiovascular Disease in 2017, and Trends, Risk Analysis, 1990 to 2017, from the Global Burden of Disease Study and Implications for Prevention

2019 ◽  
Author(s):  
Longfei Lin ◽  
Hongwei Wu ◽  
Lei Yan ◽  
Huanhuan Wang ◽  
Hongjun Yang ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Risk Analysis ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Cancer Death ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study

scholarly journals Global, regional and national burden of gout, 1990–2017: a systematic analysis of the Global Burden of Disease Study

Rheumatology ◽  
2019 ◽  
Vol 59 (7) ◽  
pp. 1529-1538 ◽  
Author(s):  
Yang Xia ◽  
Qijun Wu ◽  
Hanyuan Wang ◽  
Shuang Zhang ◽  
Yuting Jiang ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Annual Percent Change ◽  
Percent Change ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Study Results ◽  
Disease Study

Abstract Objectives The burden of gout has been increasing globally. However, little is known about the global, regional and national distribution and time trend of this disease. We present a comprehensive analysis of the Global Burden of Disease Study 2017 on gout burden estimates for 195 countries or territories between 1990 and 2017. Methods Age-standardized prevalence and disability-adjusted life-years of gout were reported between 1990 and 2017 in 195 countries and territories, and associations between these estimates and sociodemographic index (SDI) were further explored. Total and annual percent change between 1990 and 2017 were calculated to quantify the time trends of gout burden. Results Age-standardized prevalence rates (95% uncertainty interval) per 100 000 persons were 790.90 (706.10–881.90) and 253.49 (225.69–284.02) in 2017 in males and females, respectively. The annual percent change in age-standardized prevalence (males, 0.22%; females, 0.38%) and disability-adjusted life-years (males, 0.21%; females, 0.38%) of gout increased every year from 1990 to 2017, globally. The highest increase was detected in high-SDI countries, especially in high-income North America. A non-linear association was observed between burden of gout and SDI, with the lowest estimates of gout burden when SDI value was about 0.6. High BMI was the leading risk factor for the burden of gout. Conclusion These study results suggest a globally rising trajectory of gout burden between 1990 and 2017. More effective interventions, such as detailed and intensive dietary managements and other prevention strategies for reducing obesity, should be carried out to reverse this trend, especially in females and high-SDI countries.

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