Fibrin Glue/Fibronectin/Heparin-Based Delivery System of BMP2 Induces Osteogenesis in MC3T3-E1 Cells and Bone Formation in Rat Calvarial Critical-Sized Defects

2019 ◽  
Author(s):  
Qiang Ao ◽  
Shilin Wang ◽  
Qing He ◽  
Hirotomo Ten ◽  
Kenichi Oyama ◽  
...  
Keyword(s):  
Bone Formation ◽  
Fibrin Glue ◽  
Delivery System

Fibrin Glue/Fibronectin/Heparin-Based Delivery System of BMP2 Induces Osteogenesis in MC3T3-E1 Cells and Bone Formation in Rat Calvarial Critical-Sized Defects

2020 ◽  
Vol 12 (11) ◽  
pp. 13400-13410 ◽  
Author(s):  
Qiang Ao ◽  
Shilin Wang ◽  
Qing He ◽  
Hirotomo Ten ◽  
Kenichi Oyama ◽  
...  
Keyword(s):  
Bone Formation ◽  
Fibrin Glue ◽  
Delivery System

Microtomography analysis of bone formation in calvarial defects filled with gelatin sponge or fibrin glue

2013 ◽  
Author(s):  
Santana Santos Thiago de ◽  
Helena Bacha Lopes ◽  
Adriana Luiza Almeida ◽  
Marcio Mateus Beloti ◽  
Adalberto Luiz Rosa
Keyword(s):  
Bone Formation ◽  
Fibrin Glue ◽  
Gelatin Sponge ◽  
Calvarial Defects

Multiple Fibrin Glue Use in a Complicated Case of Postdural Puncture Headache Following Intrathecal Drug Delivery System Placement: A Case Report

2019 ◽  
pp. 77-81
Author(s):  
Matthew Chung
Keyword(s):  
Drug Delivery ◽  
Cerebrospinal Fluid ◽  
Drug Delivery System ◽  
Fibrin Glue ◽  
Delivery System ◽  
Epidural Blood Patch ◽  
Csf Leak ◽  
Postdural Puncture Headache ◽  
Intrathecal Drug Delivery ◽  
Blood Patch

A postdural puncture headache (PDPH) is a well-described complication after implantation of an intrathecal drug delivery system (IDDS). Treatment is typically with supportive management with the occasional need for an epidural blood patch. We describe a case of a patient with refractory muscle spasticity secondary to cerebral palsy that required a baclofen IDDS implantation and subsequently developed a PDPH. After failing conservative therapy as well as an epidural blood patch, the decision was made to attempt an epidural fibrin patch, which transiently improved her headache. Upon return of the patient’s symptoms, computed tomography myelogram demonstrated an extensive cerebrospinal fluid leak with ventral spread into the retroperitoneal space. Using a novel technique, a second epidural fibrin glue patch was administered just adjacent to the IDDS catheter insertion point, which was then successful in resolving her symptoms. Key words: Intrathecal drug delivery system, postdural puncture headache, dural tear, cerebrospinal fluid (CSF) leak, fibrin glue, epidural blood patch

scholarly journals Fibrin glue as a local drug-delivery system for bacteriophage PA5

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Evgenii Rubalskii ◽  
Stefan Ruemke ◽  
Christina Salmoukas ◽  
Andrey Aleshkin ◽  
Svetlana Bochkareva ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Fibrin Glue ◽  
Delivery System ◽  
Local Drug Delivery ◽  
Local Drug Delivery System

Cell-mediated BMP-2 release from a novel dual-drug delivery system promotes bone formation

2013 ◽  
Vol 25 (12) ◽  
pp. 1412-1421 ◽  
Author(s):  
Tie Liu ◽  
Gang Wu ◽  
Yuanna Zheng ◽  
Daniel Wismeijer ◽  
Vincent Everts ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Bone Formation ◽  
Drug Delivery System ◽  
Delivery System ◽  
Dual Drug

scholarly journals Fibrin glue as a drug delivery system

2010 ◽  
Vol 148 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Patrick P. Spicer ◽  
Antonios G. Mikos
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Fibrin Glue ◽  
Delivery System

A biodegradable polymer as a cytokine delivery system for inducing bone formation

10.1038/86715 ◽  
2001 ◽  
Vol 19 (4) ◽  
pp. 332-335 ◽  
Author(s):  
Naoto Saito ◽  
Takao Okada ◽  
Hiroshi Horiuchi ◽  
Narumichi Murakami ◽  
Jun Takahashi ◽  
...  
Keyword(s):  
Bone Formation ◽  
Delivery System ◽  
Biodegradable Polymer

Nanogel-based delivery system enhances PGE2 effects on bone formation

2007 ◽  
Vol 101 (5) ◽  
pp. 1063-1070 ◽  
Author(s):  
Norihiko Kato ◽  
Urara Hasegawa ◽  
Nobuyuki Morimoto ◽  
Yoshitomo Saita ◽  
Kazuhisa Nakashima ◽  
...  
Keyword(s):  
Bone Formation ◽  
Delivery System
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