Generalized Bayes Estimation for a SAR Model with Linear Restrictions Binding the Coefficients

2019 ◽  
Author(s):  
Sandeep Mishra ◽  
Anoop Chaturvedi
Author(s):  
Hamid Karamikabir ◽  
Mahmoud Afshari

In this paper, the generalized Bayes estimator of elliptical distribution parameter’s under asymmetric Linex error loss function is considered. The new shrinkage generalized Bayes estimator by applying wavelet transformation is investigated. We develop admissibility and minimaxity of shrinkage estimator on multivariate normal distribution.We present the simulation in order to test validity of purpose estimator.


2019 ◽  
Vol 16 (3) ◽  
pp. 193-208 ◽  
Author(s):  
Yan Hu ◽  
Guangya Zhou ◽  
Chi Zhang ◽  
Mengying Zhang ◽  
Qin Chen ◽  
...  

Background: Alzheimer's disease swept every corner of the globe and the number of patients worldwide has been rising. At present, there are as many as 30 million people with Alzheimer's disease in the world, and it is expected to exceed 80 million people by 2050. Consequently, the study of Alzheimer’s drugs has become one of the most popular medical topics. Methods: In this study, in order to build a predicting model for Alzheimer’s drugs and targets, the attribute discriminators CfsSubsetEval, ConsistencySubsetEval and FilteredSubsetEval are combined with search methods such as BestFirst, GeneticSearch and Greedystepwise to filter the molecular descriptors. Then the machine learning algorithms such as BayesNet, SVM, KNN and C4.5 are used to construct the 2D-Structure Activity Relationship(2D-SAR) model. Its modeling results are utilized for Receiver Operating Characteristic curve(ROC) analysis. Results: The prediction rates of correctness using Randomforest for AChE, BChE, MAO-B, BACE1, Tau protein and Non-inhibitor are 77.0%, 79.1%, 100.0%, 94.2%, 93.2% and 94.9%, respectively, which are overwhelming as compared to those of BayesNet, BP, SVM, KNN, AdaBoost and C4.5. Conclusion: In this paper, we conclude that Random Forest is the best learner model for the prediction of Alzheimer’s drugs and targets. Besides, we set up an online server to predict whether a small molecule is the inhibitor of Alzheimer's target at http://47.106.158.30:8080/AD/. Furthermore, it can distinguish the target protein of a small molecule.


Author(s):  
Ulf Grenander ◽  
Michael I. Miller

Pattern Theory provides a comprehensive and accessible overview of the modern challenges in signal, data, and pattern analysis in speech recognition, computational linguistics, image analysis and computer vision. Aimed at graduate students in biomedical engineering, mathematics, computer science, and electrical engineering with a good background in mathematics and probability, the text includes numerous exercises and an extensive bibliography. Additional resources including extended proofs, selected solutions and examples are available on a companion website. The book commences with a short overview of pattern theory and the basics of statistics and estimation theory. Chapters 3-6 discuss the role of representation of patterns via condition structure. Chapters 7 and 8 examine the second central component of pattern theory: groups of geometric transformation applied to the representation of geometric objects. Chapter 9 moves into probabilistic structures in the continuum, studying random processes and random fields indexed over subsets of Rn. Chapters 10 and 11 continue with transformations and patterns indexed over the continuum. Chapters 12-14 extend from the pure representations of shapes to the Bayes estimation of shapes and their parametric representation. Chapters 15 and 16 study the estimation of infinite dimensional shape in the newly emergent field of Computational Anatomy. Finally, Chapters 17 and 18 look at inference, exploring random sampling approaches for estimation of model order and parametric representing of shapes.


Symmetry ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 19
Author(s):  
Hsiuying Wang

High-dimensional data recognition problem based on the Gaussian Mixture model has useful applications in many area, such as audio signal recognition, image analysis, and biological evolution. The expectation-maximization algorithm is a popular approach to the derivation of the maximum likelihood estimators of the Gaussian mixture model (GMM). An alternative solution is to adopt a generalized Bayes estimator for parameter estimation. In this study, an estimator based on the generalized Bayes approach is established. A simulation study shows that the proposed approach has a performance competitive to that of the conventional method in high-dimensional Gaussian mixture model recognition. We use a musical data example to illustrate this recognition problem. Suppose that we have audio data of a piece of music and know that the music is from one of four compositions, but we do not know exactly which composition it comes from. The generalized Bayes method shows a higher average recognition rate than the conventional method. This result shows that the generalized Bayes method is a competitor to the conventional method in this real application.


2021 ◽  
Vol 11 (10) ◽  
pp. 4429
Author(s):  
Ana Šarčević ◽  
Damir Pintar ◽  
Mihaela Vranić ◽  
Ante Gojsalić

The prediction of sport event results has always drawn attention from a vast variety of different groups of people, such as club managers, coaches, betting companies, and the general population. The specific nature of each sport has an important role in the adaption of various predictive techniques founded on different mathematical and statistical models. In this paper, a common approach of modeling sports with a strongly defined structure and a rigid scoring system that relies on an assumption of independent and identical point distributions is challenged. It is demonstrated that such models can be improved by introducing dynamics into the match models in the form of sport momentums. Formal mathematical models for implementing these momentums based on conditional probability and empirical Bayes estimation are proposed, which are ultimately combined through a unifying hybrid approach based on the Monte Carlo simulation. Finally, the method is applied to real-life volleyball data demonstrating noticeable improvements over the previous approaches when it comes to predicting match outcomes. The method can be implemented into an expert system to obtain insight into the performance of players at different stages of the match or to study field scenarios that may arise under different circumstances.


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