Penalizing Lies and Optimal Monitoring

2019 ◽  
Author(s):  
Christian Salas
Keyword(s):  
Optimal Monitoring

Configuring a seismographic network for optimal monitoring of fault lines and multiple sources

1995 ◽  
Vol 85 (6) ◽  
pp. 1847-1857
Author(s):  
David M. Steinberg ◽  
Nitzan Rabinowitz ◽  
Yair Shimshoni ◽  
Daphna Mizrachi
Keyword(s):  
Statistical Theory ◽  
Experimental Design ◽  
Point Source ◽  
High Precision ◽  
Optimality Criterion ◽  
Network Configuration ◽  
Multiple Sources ◽  
Optimal Monitoring ◽  
Optimal Network ◽  
Seismographic Network

Abstract The geometric configuration of a seismographic network has important consequences for the ability to determine hypocenters with high precision. We present a method for optimal configuration when the network must monitor a system of faults. Our optimality criterion is drawn from the statistical theory of experimental design and can be effeciently maximized using an extension of the DETMAX algorithm. Our work generalizes that of Rabinowitz and Steinberg (1990), which treated the problem of optimal network configuration for monitoring a point source.

scholarly journals Excision of intra-dural dorsal spine meningioma with intra-operative neuromonitoring in a patient with post-pneumonectomy status- an anaesthetic challenge

2021 ◽  
Vol 8 (4) ◽  
pp. 615-618
Author(s):  
Amruta M Kulkarni ◽  
Vijay L Shetty
Keyword(s):  
Evoked Potentials ◽  
Female Patient ◽  
Neurological Deficit ◽  
Dorsal Spine ◽  
Anaesthetic Technique ◽  
Physiological Changes ◽  
Neurological Damage ◽  
Complete Excision ◽  
Optimal Monitoring ◽  
Anaesthetic Agents

Post-pneumonectomy status is associated with various anatomical and physiological changes. Intra-operative neuromonitoring allows for safe neurosurgery with minimal neurological damage. Intra-operative neuromonitoring requires that the anaesthetic technique be modified taking into considerations the effects of various anaesthetic agents on evoked potentials to allow for optimal monitoring. We present a case of 65 year old female patient, with post-pneumonectomy status posted for excision of intra-dural D10 meningioma with intra-operative neuromonitoring. The case was successfully conducted with meticulous planning and preparation with complete excision of lesion and no neurological deficit post-operatively.

scholarly journals Optimal Monitoring of Multiple Agents via Time Sequence-Based Modeling

2018 ◽  
Vol 11 (3) ◽  
pp. 169-173 ◽  
Author(s):  
Ryo MASUDA ◽  
Koichi KOBAYASHI ◽  
Yuh YAMASHITA
Keyword(s):  
Time Sequence ◽  
Multiple Agents ◽  
Optimal Monitoring

scholarly journals Simulation modelling to identify optimal monitoring strategies: the use of the elf biomarker in liver disease monitoring

Trials ◽  
2013 ◽  
Vol 14 (S1) ◽  
Author(s):  
Alice Sitch ◽  
Jac Dinnes ◽  
Julie Parkes ◽  
Walter Gregory ◽  
Jenny Hewison ◽  
...  
Keyword(s):  
Liver Disease ◽  
Simulation Modelling ◽  
Disease Monitoring ◽  
Optimal Monitoring ◽  
Monitoring Strategies

scholarly journals GROWTH AND WELFARE EFFECTS OF MACROPRUDENTIAL REGULATION

2018 ◽  
Vol 23 (8) ◽  
pp. 3140-3162 ◽  
Author(s):  
Pierre-Richard Agénor
Keyword(s):  
Systemic Risk ◽  
Overlapping Generations ◽  
Welfare Effects ◽  
Financial Supervision ◽  
Overlapping Generations Model ◽  
Macroprudential Regulation ◽  
Bank Monitoring ◽  
Investment Projects ◽  
Optimal Monitoring ◽  
Reserve Ratio

This paper studies the growth and welfare effects of macroprudential regulation in an overlapping generations model of endogenous growth with banking and agency costs. Indivisible investment projects combine with informational imperfections to create a double moral hazard problem à la Holmström–Tirole and a role for bank monitoring. When the optimal monitoring intensity is endogenously determined, an increase in the required reserve ratio (motivated by systemic risk considerations) has conflicting effects on investment and growth. On one hand, requiring banks to put away a fraction of the deposits that they receive reduces the supply of loanable funds. On the other, a higher required ratio raises incentives to save and mitigates banks' incentives to monitor, thereby lowering monitoring costs and freeing up resources to increase lending. In addition, it may mitigate the systemic risk externality associated with excessive leverage. This trade-off can be internalized by choosing the required reserve ratio that maximizes growth and welfare. However, the risk of disintermediation means that in practice financial supervision may also need to be strengthened, and the perimeter of regulation broadened, if the optimal ratio is relatively high.

Chronic myeloid leukaemia

2020 ◽  
pp. 93-112
Author(s):  
Tariq I. Mughal
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Kinase Inhibitors ◽  
Treatment Algorithm ◽  
Chromosome 9 ◽  
Balanced Translocation ◽  
Optimal Monitoring ◽  
Advanced Phase ◽  
Cytogenetic Remission ◽  
Initial Choice

Chronic myeloid leukaemia (CML) was recognized in the 1970s by Janet Rowley to be a genetically simple malignancy; resulting as a consequence of a balanced translocation between chromosome 9 and 22. This provided vital insights into the molecular aberration, in the 1990s, which ushered in the current ‘precision medicine’ era, not only for patients of CML, but for cancers in general. As a result, today, a personalized treatment algorithm is available for all newly diagnosed patients with CML. Treatment involves a choice of three first-line orally administered tyrosine kinase inhibitors (TKIs) and two effective next-line TKIs that should be used based on risk stratification, comorbidities, the side effects profile, and the BCR-ABL1 genotype. Regardless of the initial choice of TKI, the vast majority of patients achieve a durable complete cytogenetic remission, with a lifespan approaching that of the general population. In most instances the medication must be continued indefinitely, and a principal challenge now, is to develop strategies to stop TKIs safely and effectively. Challenges remain in how to achieve optimal monitoring of patients with CML on treatment and in achieving a better understanding of the mechanisms and treatment of patients with advanced phase disease. This chapter addresses these questions as well as the concomitant topical issues in CML.

scholarly journals In vivo non-invasive near-infrared spectroscopy distinguishes normal, post-stroke, and botulinum toxin treated human muscles

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Antonio Currà ◽  
Riccardo Gasbarrone ◽  
Alessandra Cardillo ◽  
Francesco Fattapposta ◽  
Paolo Missori ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Near Infrared ◽  
Comprehensive Evaluation ◽  
Botulinum Toxin Injection ◽  
Principal Component ◽  
Short Wave ◽  
Post Stroke ◽  
Non Invasive ◽  
Optimal Monitoring

AbstractIn post-stroke hemiparesis, neural impairment alters muscle control, causing abnormal movement and posture in the affected limbs. A decrease in voluntary use of the paretic arm and flexed posture during rest also induce secondary tissue transformation in the upper limb muscles. To obtain a specific, accurate, and reproducible marker of the current biological status of muscles, we collected visible (VIS) and short-wave Infrared (SWIR) reflectance spectra in vivo using a portable spectroradiometer (350–2500 nm), which provided the spectral fingerprints of the elbow flexors and extensors. We compared the spectra for the affected and unaffected sides in 23 patients with post-stroke hemiparesis (25–87 years, 8 women) and eight healthy controls (33–87 years, 5 women). In eight patients, spectra were collected before and after botulinum toxin injection. Spectra underwent off-line preprocessing, principal component analysis, and partial least-squares discriminant analysis. Spectral fingerprints discriminated the muscle (biceps vs. triceps), neurological condition (normal vs. affected vs. unaffected), and effect of botulinum toxin treatment (before vs. 30 to 40 days vs. 110 to 120 days after injection). VIS-SWIR spectroscopy proved valuable for non-invasive assessment of optical properties in muscles, enabled more comprehensive evaluation of hemiparetic muscles, and provided optimal monitoring of the effectiveness of medication.

scholarly journals Optimal Monitoring Design

Econometrica ◽  
2020 ◽  
Vol 88 (5) ◽  
pp. 2075-2107 ◽  
Author(s):  
George Georgiadis ◽  
Balazs Szentes
Keyword(s):  
Information Acquisition ◽  
Minimal Cost ◽  
Threshold Policy ◽  
Agent Model ◽  
Monitoring Design ◽  
Effort Level ◽  
Optimal Monitoring ◽  
Principal Agent Model ◽  
Optimal Information ◽  
Acquisition Strategy

This paper considers a Principal–Agent model with hidden action in which the Principal can monitor the Agent by acquiring independent signals conditional on effort at a constant marginal cost. The Principal aims to implement a target effort level at minimal cost. The main result of the paper is that the optimal information‐acquisition strategy is a two‐threshold policy and, consequently, the equilibrium contract specifies two possible wages for the Agent. This result provides a rationale for the frequently observed single‐bonus wage contracts.

An Optimal Monitoring Program for Obtaining Voltage Sag System Indexes

2006 ◽  
Vol 21 (1) ◽  
pp. 378-384 ◽  
Author(s):  
G. Olguin ◽  
F. Vuinovich ◽  
M.H.J. Bollen
Keyword(s):  
Monitoring Program ◽  
Voltage Sag ◽  
Optimal Monitoring
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