Global Incidence Trends in Very-Early-, Early-, and Late-Onset Primary Liver Cancer by Sex, Region, and Aetiology: A Study Based on Global Burden of Disease Study 2017

2019 ◽  
Author(s):  
Zhenqiu Liu ◽  
Chen Suo ◽  
Xianhua Mao ◽  
Yanfeng Jiang ◽  
Li Jin ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Burden Of Disease ◽  
Late Onset ◽  
Primary Liver Cancer ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Incidence Trends ◽  
Disease Study

scholarly journals The Burden and Trends of Primary Liver Cancer Caused by Specific Etiologies from 1990 to 2017 at the Global, Regional, National, Age, and Sex Level Results from the Global Burden of Disease Study 2017

Liver Cancer ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 563-582 ◽  
Author(s):  
Longfei Lin ◽  
Lei Yan ◽  
Yuling Liu ◽  
Changhai Qu ◽  
Jian Ni ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Incidence ◽  
Burden Of Disease ◽  
Primary Liver Cancer ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Targeted Prevention ◽  
Cancer Burden ◽  
Incidence And Mortality ◽  
Disease Study

Background: Liver cancer is one of the leading causes of cancer-related deaths worldwide. The primary causes of liver cancer include hepatitis B virus (HBV), hepatitis C virus (HCV), alcohol consumption, nonalcoholic fatty liver disease, and other factors. Aims: The objective of this study was to evaluate the global and sex-, age-, region-, country-, and etiology-related liver cancer burden, as well as the trends in liver cancer caused by different etiologies. Methods: The causes of liver cancer from 1990 to 2017, including global, regional, and national liver cancer incidence, mortality, and etiology, were collected from the Global Burden of Disease study 2017, and the time-dependent change in the trends of liver cancer burden was evaluated by annual percentage change. Results: The global liver cancer incidence and mortality have been increasing. There were 950,000 newly-diagnosed liver cancer cases and over 800,000 deaths in 2017, which is more than twice the numbers recorded in 1990. HBV and HCV are the major causes of liver cancer. HBV is the major risk factor of liver cancer in Asia, while HCV and alcohol abuse are the major risk factors in the high sociodemographic index and high human development index regions. The mean onset age and incidence of liver cancer with different etiologies have gradually increased in the past 30 years. Conclusions: The global incidence is still rising and the causes have national, regional, or population specificities. More targeted prevention strategies must be developed for the different etiologic types in order to reduce liver cancer burden.

scholarly journals Tuberculosis Incidence Trends from 1990 to 2017 Highlight Impact of Drug Resistance: Results from the Global Burden of Disease Study

2020 ◽  
Author(s):  
Zejin Ou ◽  
Wenqiao He ◽  
Danfeng Yu ◽  
Yongzhi Li ◽  
Yuanhao Liang ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Multidrug Resistant ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Incidence Trends ◽  
Resistant Tuberculosis ◽  
Extensively Drug Resistant ◽  
Mdr Tb ◽  
Disease Study ◽  
Increasing Trends

Abstract Objectives This study aimed to determine the global incidence trends of tuberculosis (TB) from 1990 to 2017.Methods Data was obtained from the Global Burden of Disease (GBD) study. The estimated annual percentage changes (EAPCs) were calculated with the age-standardised incidence rate (ASIR) to estimate trends in incidence of TB, including multidrug-resistant TB (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB).Results Globally, the number of TB cases was 8965.81×103 in 2017, with a 9.42% increase since 1990. The ASIR for TB showed a decreasing trend from 1990 to 2017 (EAPC = −1.19, 95% confidence interval [CI]: −1.32 to −1.07). Meanwhile, decreasing trends were observed in 162 countries/territories, particularly in Ethiopia and China where EAPCs were −4.51 (95%CI: −5.22 to −3.80) and −4.21 (95%CI: −4.98 to −3.44), respectively. However, obvious increasing trends of MDR-TB cases occurred in areas with low and low-middle sociodemographic indexes (SDI), with EAPCs of 7.97 (95%CI: 2.47 to 13.75) and 6.30 (95%:1.17 to 11.68), respectively. The ASIR for XDR-TB showed pronounced increasing trends globally from 1991 to 2017, with an EAPC of 11.74 (95%CI: 7.50 to 16.16). The largest rising trends of XDR-TB were observed in Kyrgyzstan (EAPC = 31.06, 95%CI: 23.07 to 39.57), followed by Azerbaijan and Uzbekistan.Conclusions There was a decreasing trend for TB incidence worldwide, although it was more pronounced in specific countries and regions. However, the rapidly rising trends of MDR-TB and XDR-TB cases in low and low-middle SDI areas and countries may have an adverse impact on the global control of TB.

scholarly journals The trends in global, regional, and national incidence of pneumoconiosis caused by different etiologies: an analysis from the Global Burden of Disease Study 2017

2019 ◽  
Author(s):  
Peng Shi ◽  
Xiaoyue Xing ◽  
Shuhua Xi ◽  
Hongmei Jing ◽  
Jiamei Yuan ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Burden Of Disease ◽  
Incidence Rates ◽  
Global Burden Of Disease ◽  
Health Concern ◽  
Global Burden ◽  
Incidence Trends ◽  
The World ◽  
Disease Study ◽  
Incident Cases

Abstract Pneumoconiosis has the potential to cause progressive and permanent physical disability. And continues to be one of major public health concern across the world. However, our literature searches identified a scarcity of data about global prevalence of pneumoconiosis. Accurate data on the incidence of pneumoconiosis is critical for health resource planning and health policy development. We therefore aimed to determine the pattern of pneumoconiosis incidence and temporal trends. Methods: Annual incident cases and age standardized incidence rates on pneumoconiosis etiology between 1990-2017 were collected from the Global Burden of Disease Study 2017. We calculate the average annual percentage changes of age standardized incidence rates by sex, region, and etiology to determine incidence trends of pneumoconiosis. Results: Globally, the number of pneumoconiosis cases increased 66.0% from 36,186 in 1990 to 60,055 in 2017. The overall age standardized incidence rate decreased by an average 0.6% (95% CI: 0.5%, 0.6%) per year in the same period. The age standardized incidence rate of silicosis, asbestosis, and other pneumoconiosis decreased between 1990 and 2017. The corresponding average annual percentage changes were -0.8%, -0.9%, and -0.5%, respectively. The age standardized incidence rate of asbestosis displayed an increasing trend. At the same time, we also found a significant negative association was found between average annual percentage changes and socio-demographic indexs when the socio-demographic index above 0.7. Conclusions: Pneumoconiosis remains a major occupational health illnesses in the world. Incidence patterns of pneumoconiosis caused by different etiologies were heterogeneous across regions and countries. We observed an unfavorable trend that asbestosis was predominant in countries with a high socio-demographic index, though we have attained great achievements in silicosis and coal workers’ pneumoconiosis prevention. The information in this study suggests that some countries should establish more targeted and specific strategies to forestall the increase in pneumoconiosis.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASR trends also varied considerably by regions and countries. The increase in ASR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88).Conclusions: Both the number of incident cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88).Conclusions: Both the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASR trends also varied considerably by regions and countries. The increase in ASR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88). Conclusions: Both the number of incident cases and ASR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

scholarly journals Trends in the incidence of diabetes mellitus: results from the Global Burden of Disease Study 2017 and implications for diabetes mellitus prevention

2020 ◽  
Author(s):  
Jinli Liu ◽  
Zhen-Hu Ren ◽  
Hua Qiang ◽  
Jine Wu ◽  
Mingwang Shen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Burden Of Disease ◽  
Temporal Trends ◽  
Global Burden Of Disease ◽  
Public Health Issue ◽  
Global Burden ◽  
Common Chronic Disease ◽  
Incidence Trends ◽  
Disease Study ◽  
Incident Cases

Abstract Backgroud: Diabetes mellitus is a common chronic disease and a severe public health issue. The incidence trends for type 1 diabetes (TIDM) and type 2 diabetes (T2DM) have rarely been studied on a global scale. We aimed to determine the temporal and geographical trends of diabetes globally.Methods: Data on diabetes mellitus, including incidence, prevalence from 1990 to 2017 were obtained from the 2017 Global Burden of Disease study. We calculated the estimated annual percentage changes (EAPCs) in age-standardized incidence rate (ASIR) of diabetes mellitus according to sex, region, and disease type.Results: The worldwide incident cases of diabetes mellitus has increased by 102.9% from 11,303,084 cases in 1990 to 22,935,630 cases in 2017 worldwide, while the ASIR increased from 233.58/100,000 persons (95% UI, 218.95–249.37) to 284.56/100,000 persons (95% UI, 262.17–309.71) in this period [EAPC=0.87, 95% confidence interval (CI):0.79–0.96]. The global ASIRs of T1DM and T2DM both demonstrated significant increase during 1990-2017, with EAPCs of 0.34 (95% CI:0.30–0.39) and 0.89 (95% CI:0.80–0.97), respectively. The ASIR trends also varied considerably by regions and countries. The increase in ASIR was greatest in high sociodemographic index regions (EAPC=1.05, 95% CI:0.92–1.17) and lowest in low-SDI regions (EAPC=0.79, 95% CI:0.71–0.88). Conclusions: Both the number of incident cases and ASIR of diabetes mellitus increased significantly during 1990-2017 worldwide, but the temporal trends varied markedly across regions and countries.

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