Evaluating the Potential of Pregnant Women As a Sentinel Population for Malaria Surveillance

2019 ◽  
Author(s):  
Nina C. Brunner ◽  
Frank Chacky ◽  
Renata Mandike ◽  
Ally Mohamed ◽  
Manuela Runge ◽  
...  
2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Nina C. Brunner ◽  
Frank Chacky ◽  
Renata Mandike ◽  
Ally Mohamed ◽  
Manuela Runge ◽  
...  

Abstract Background With increasing spatial heterogeneity of malaria transmission and a shift of the disease burden towards older children and adults, pregnant women attending antenatal care (ANC) have been proposed as a pragmatic sentinel population for malaria surveillance. However, the representativeness of routine ANC malaria test-positivity and its relationship with prevalence in other population subgroups are yet to be investigated. Methods Monthly ANC malaria test-positivity data from all Tanzanian health facilities for January 2014 to May 2016 was compared to prevalence data from the School Malaria Parasitaemia Survey 2015, the Malaria Indicator Survey (MIS) 2015/16, the Malaria Atlas Project 2015, and a Bayesian model fitted to MIS data. Linear regression was used to describe the difference between malaria test-positivity in pregnant women and respective comparison groups as a function of ANC test-positivity and potential covariates. Results The relationship between ANC test-positivity and survey prevalence in children follows spatially and biologically meaningful patterns. However, the uncertainty of the relationship was substantial, particularly in areas with high or perennial transmission. In comparison, modelled data estimated higher prevalence in children at low transmission intensities and lower prevalence at higher transmission intensities. Conclusions Pregnant women attending ANC are a pragmatic sentinel population to assess heterogeneity and trends in malaria prevalence in Tanzania. Yet, since ANC malaria test-positivity cannot be used to directly predict the prevalence in other population subgroups, complementary community-level measurements remain highly relevant.


2021 ◽  
Vol 8 ◽  
Author(s):  
Humera Qureshi ◽  
Muhammad Imran Khan ◽  
Akhlaq Ahmad ◽  
Usman Ayub Awan ◽  
Aamer Ali Khattak ◽  
...  

Background: Malaria among pregnant women is one of the major causes of maternal and infant mortality and morbidity, especially in high-risk areas. Therefore, our study identified the burden of malaria for pregnant women, non-pregnant women, and children under 5 years of age, and malaria service health facilities in Bannu district, Khyber Pakhtunkhwa, Pakistan.Methods: A cross-sectional study was conducted. In this survey, 15,650 individuals were surveyed, and 1,283 were malaria-positive detected. The data were collected from 80 different healthcare centers. SPSS version 23 was used for data analysis. ArcGIS version 10.8 was used for study area mapping.Results: Malaria was detected in 23.3% of children under five, 4.4% of pregnant women, and 72.3% of non-pregnant women, respectively. Moreover, P. falciparum, P. vivax, and mixed infection had a prevalence of 2.1, 96.8, and 1.1%. The most often used and effective medications to treat malaria were chloroquine (29.7%) and primaquine (69.4%).Conclusion: This study's findings depict that malaria's prevalence in the non-pregnant women's group was high. Additionally, P. vivax infection was found to be more prevalent than other types of malaria infection. Due to the scarcity of healthcare facilities in this endemic region, special attention should be directed to strengthening the malaria surveillance and eradication programs.


2019 ◽  
Vol 35 (9) ◽  
pp. 677-686 ◽  
Author(s):  
Alfredo Mayor ◽  
Clara Menéndez ◽  
Patrick G.T. Walker

Vaccine ◽  
2005 ◽  
Vol 23 (25) ◽  
pp. 3243-3246 ◽  
Author(s):  
Filippa Bonura ◽  
Marco Sorgi ◽  
Anna Maria Perna ◽  
Giuseppe Puccio ◽  
Fabio Tramuto ◽  
...  

1998 ◽  
Vol 5 (1) ◽  
pp. 143A-143A ◽  
Author(s):  
G DILDY ◽  
C LOUCKS ◽  
T PORTER ◽  
C SULLIVAN ◽  
M BELFORT ◽  
...  

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