Categorization of Pancreatic B-Cells Capacity in Overweight and Obese Patients via Oral Glucose Tolerance Test Using K-Means Clustering Method

2019 ◽  
Author(s):  
Li Li ◽  
Qifa Song ◽  
Xi Yang
Keyword(s):  
B Cells ◽  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Obese Patients ◽  
Oral Glucose Tolerance ◽  
Clustering Method ◽  
Pancreatic B Cells

1159-P: One-Hour Glucose during Oral Glucose Tolerance Test Predicts Hyperglycemia Relapse in Black Obese Patients with Hyperglycemic Crises

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 1159-P
Author(s):  
RAM JAGANNATHAN ◽  
DAWN SMILEY-BYRD ◽  
DARKO STEFANOVSKI ◽  
GUILLERMO E. UMPIERREZ ◽  
PRIYATHAMA VELLANKI
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Obese Patients ◽  
Oral Glucose Tolerance

scholarly journals The neuropeptide 26RFa in the human gut and pancreas: potential involvement in glucose homeostasis

2019 ◽  
Vol 8 (7) ◽  
pp. 941-951 ◽  
Author(s):  
Gaëtan Prévost ◽  
Marie Picot ◽  
Marie-Anne Le Solliec ◽  
Arnaud Arabo ◽  
Hind Berrahmoune ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Glucose Homeostasis ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Blood Levels ◽  
Oral Glucose ◽  
Obese Patients ◽  
Oral Glucose Tolerance ◽  
Gastric Glands

Objective Recent studies performed in mice revealed that the neuropeptide 26RFa regulates glucose homeostasis by acting as an incretin and by increasing insulin sensitivity. However, in humans, an association between 26RFa and the regulation of glucose homeostasis is poorly documented. In this study, we have thus investigated in detail the distribution of 26RFa and its receptor, GPR103, in the gut and the pancreas, and determined the response of this peptidergic system to an oral glucose challenge in obese patients. Design and methods Distribution of 26RFa and GPR103 was examined by immunohistochemistry using gut and pancreas tissue sections. Circulating 26RFa was determined using a specific radioimmunoassay in plasma samples collected during an oral glucose tolerance test. Results 26RFa and GPR103 are present all along the gut but are more abundant in the stomach and duodenum. In the stomach, the peptide and its receptor are highly expressed in the gastric glands, whereas in the duodenum, ileum and colon they are present in the enterocytes and the goblet cells. In the pancreatic islets, the 26RFa/GPR103 system is mostly present in the β cells. During an oral glucose tolerance test, plasma 26RFa profile is different between obese patients and healthy volunteers, and we found strong positive correlations between 26RFa blood levels and the BMI, and with various parameters of insulin secretion and insulin resistance. Conclusion The present data suggest an involvement of the 26RFa/GPR103 peptidergic system in the control of human glucose homeostasis.

Plasma Beta-Endorphin in Response to Oral Glucose Tolerance Test in Obese Patients

1987 ◽  
Vol 19 (05) ◽  
pp. 204-207 ◽  
Author(s):  
D. Scavo ◽  
F. Facchinetti ◽  
C. Barletta ◽  
F. Petraglia ◽  
R. Buzzetti ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Obese Patients ◽  
Oral Glucose Tolerance ◽  
Beta Endorphin

Abstract #873: Association of Patterns in the Oral Glucose Tolerance Test and Different Clinical Features in Patients with Insulinoma

2005 ◽  
Vol 11 ◽  
pp. 28
Author(s):  
Fanny Rodriguez Vallejo ◽  
Juan Manuel Rios Torres ◽  
Francisco J. Gomez-Pérez ◽  
Juan A. Rull Rodrigo ◽  
Bernardo Pérez Enriquez
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Clinical Features ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance

Oral glucose tolerance test or HbA1c assessment of subjects with coronary disease verified by angiography

2016 ◽  
Author(s):  
Zivkovic Teodora Beljic ◽  
Biljana Jojic ◽  
Jelic Marina Andjelic ◽  
Goran Loncar ◽  
Aleksandar Davidovic ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Coronary Disease ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance
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