1p19q Gene Transcription Profiles Closely Correlated to Malignancy and Prognosis of 1p/19q Non-Codeletion Gliomas

2018 ◽  
Author(s):  
Rui-Chao Chai ◽  
Ke-Nan Zhang ◽  
Fan Wu ◽  
Yu-Qing Liu ◽  
Zheng Zhao ◽  
...  
Keyword(s):  
Gene Transcription ◽  
Transcription Profiles

scholarly journals Altered gene transcription profiles in fibroblasts harboring either TK2 or DGUOK mutations indicate compensatory mechanisms

2009 ◽  
Vol 315 (8) ◽  
pp. 1429-1438 ◽  
Author(s):  
Joan Villarroya ◽  
Carme de Bolós ◽  
Anna Meseguer ◽  
Michio Hirano ◽  
Maya R. Vilà
Keyword(s):  
Gene Transcription ◽  
Compensatory Mechanisms ◽  
Transcription Profiles ◽  
Altered Gene

Chemosensory mediated behaviors and gene transcription profiles in wild yellow perch (Perca flavescens) from metal contaminated lakes

2014 ◽  
Vol 106 ◽  
pp. 239-245 ◽  
Author(s):  
Ali Azizishirazi ◽  
William A. Dew ◽  
Berenice Bougas ◽  
Mehdi Dashtban ◽  
Louis Bernatchez ◽  
...  
Keyword(s):  
Gene Transcription ◽  
Yellow Perch ◽  
Perca Flavescens ◽  
Transcription Profiles

Cytokine and gene transcription profiles of immune responses elicited by HIV lipopeptide vaccine in HIV-negative volunteers

AIDS ◽  
2013 ◽  
Vol 27 (9) ◽  
pp. 1421-1431 ◽  
Author(s):  
Laura Richert ◽  
Sophie Hue ◽  
Hakim Hocini ◽  
Mathieu Raimbault ◽  
Christine Lacabaratz ◽  
...  
Keyword(s):  
Immune Responses ◽  
Gene Transcription ◽  
Transcription Profiles ◽  
Hiv Negative

scholarly journals Gene transcription profiles, global DNA methylation and potential transgenerational epigenetic effects related to Zn exposure history in Daphnia magna

2010 ◽  
Vol 158 (10) ◽  
pp. 3323-3329 ◽  
Author(s):  
Michiel B. Vandegehuchte ◽  
Dieter De Coninck ◽  
Tine Vandenbrouck ◽  
Wim M. De Coen ◽  
Colin R. Janssen
Keyword(s):  
Dna Methylation ◽  
Daphnia Magna ◽  
Gene Transcription ◽  
Global Dna Methylation ◽  
Transcription Profiles ◽  
Epigenetic Effects ◽  
Exposure History

Construction of a cDNA-based microarray for Drosophila melanogaster: a comparison of gene transcription profiles from SL2 and Kc167 cells

Genome ◽  
2003 ◽  
Vol 46 (5) ◽  
pp. 879-892 ◽  
Author(s):  
Scott J Neal ◽  
Meredith L Gibson ◽  
Anthony K.-C So ◽  
J Timothy Westwood
Keyword(s):  
Drosophila Melanogaster ◽  
Cell Lines ◽  
Dna Microarray ◽  
Gene Transcription ◽  
Expression Profiles ◽  
Dna Amplification ◽  
Berkeley Drosophila Genome Project ◽  
Drosophila Genome ◽  
Drosophila Cell ◽  
Transcription Profiles

We have constructed a DNA microarray that represents approximately 6900 of the estimated 13 598 genes in the Drosophila melanogaster genome. The microarray contains 5756 target cDNAs from the Berkeley Drosophila Genome Project, 1078 cDNAs from the National Institutes of Health Drosophila testis cDNA library, and 546 gene fragments that were amplified from genomic DNA. The methods for DNA amplification and microarray manufacture are presented. Academic researchers can obtain the microarray from the Canadian Drosophila Microarray Centre. To evaluate the utility of these arrays, we compared the gene transcription profiles of two commonly used Drosophila cell lines. Analysis revealed that 5412 spot pairs gave signals consistently above the average background in Kc167 cells, whereas 5636 spot pairs met this criterion in SL2 cells. When the expression profiles of the cell lines were compared, 1437 genes displayed at least a 1.5-fold difference, and 170 genes had a threefold or greater difference between the two cell lines. In each case, with respect to Kc167 when compared with SL2 cells, the number of genes that were upregulated was nearly equal to the number of downregulated genes. This result demonstrates that despite the similar embryonic derivation of both cell lines, their transcriptional profiles are very different.Key words: DNA microarray, Drosophila, transcriptional regulation, SL2, Kc167.

scholarly journals Detecting genome-wide gene transcription profiles associated with high pollution burden in the critically endangered European eel

2013 ◽  
Vol 132-133 ◽  
pp. 157-164 ◽  
Author(s):  
J.M. Pujolar ◽  
M. Milan ◽  
I.A.M. Marino ◽  
F. Capoccioni ◽  
E. Ciccotti ◽  
...  
Keyword(s):  
Gene Transcription ◽  
Critically Endangered ◽  
European Eel ◽  
Transcription Profiles ◽  
Genome Wide ◽  
High Pollution

Variation in gene expression profiles of peripheral blood mononuclear cells from healthy volunteers

2005 ◽  
Vol 22 (3) ◽  
pp. 402-411 ◽  
Author(s):  
John J. Eady ◽  
Gary M. Wortley ◽  
Yvette M. Wormstone ◽  
Jackie C. Hughes ◽  
Siân B. Astley ◽  
...  
Keyword(s):  
Gene Transcription ◽  
Peripheral Blood Mononuclear Cells ◽  
Peripheral Blood ◽  
Mononuclear Cells ◽  
Interindividual Variation ◽  
Human Tissues ◽  
Healthy Human ◽  
Peripheral Blood Mononuclear ◽  
Transcription Profiles ◽  
Blood Mononuclear Cells

The normal degree of intra- and interindividual variation in gene transcription profiles of healthy human tissues has not been extensively investigated. In the study described here, microarrays were employed to analyze gene transcription in peripheral blood mononuclear cells prepared from serial blood samples that had been obtained, at weekly intervals, from apparently healthy human volunteers. Transcript levels for the majority of genes examined were found to be remarkably consistent within samples from a single donor. Conversely, marked differences were observed in samples obtained from different donors. Genes that exhibited differential expression dependent on sex, age, body mass index, and the presence of varying proportions of different leukocyte subsets were identified. These results emphasize the important contributions of genetic and environmental factors, as well as varying representation of different cell types, in determining the overall gene transcriptional profiles of human tissues. However, the study also provides evidence that, within an individual, the gene transcription profiles of sampled tissues can be comparatively stable over time.

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