The Predictive Value of Left Versus Right Adrenal Volume Ratio(L/Rv) in Discrimination between AVS Confirmed Unilateral and Bilateral Primary Aldosteronism

2018 ◽  
Author(s):  
Sicheng Li ◽  
Huaiqiang Sun ◽  
Lifen Ma ◽  
Yuchun Zhu ◽  
Wei Xie ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Predictive Value ◽  
Volume Ratio ◽  
Adrenal Volume

Predicting the risk of respiratory distress in newborns with congenital pulmonary malformations

2021 ◽  
pp. 2100949
Author(s):  
Christophe Delacourt ◽  
Nathalie Bertille ◽  
Laurent J. Salomon ◽  
Makan Rashenas ◽  
Alexandra Benachi ◽  
...  
Keyword(s):  
Respiratory Distress ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Volume Ratio ◽  
Predictive Ability ◽  
Population Based ◽  
Term Infants ◽  
Predictive Variable ◽  
Study Results ◽  
Roc Area

ObjectivesMost children with prenatally diagnosed congenital pulmonary malformations (CPM) are asymptomatic at birth. We aimed to develop a parsimonious prognostic model for predicting the risk of neonatal respiratory distress (NRD) in preterm and term infants with CPM, based on the prenatal attributes of the malformation.MethodsMALFPULM is a prospective population-based nationally representative cohort including 436 pregnant women. The main predictive variable was the CPM volume ratio (CVR) measured at diagnosis (CVR first) and the highest CVR measured (CVR max). Separate models were estimated for preterm and term infants and were validated by bootstrapping.ResultsIn total, 67 of the 383 neonates studied (17%) had NRD. For infants born at term (>37 weeks, N=351), the most parsimonious model included CVR max as the only predictive variable (ROC area: 0.70±0.04, negative predictive value: 0.91). The probability of NRD increased linearly with increasing CVR max and remained below 10% for CVR max<0.4. In preterm infants (N=32), both CVR max and gestational age were important predictors of the risk of NRD (ROC area: 0.85±0.07). Models based on CVR first had a similar predictive ability.ConclusionsPredictive models based exclusively on CVR measurements had a high negative predictive value in infants born at term. Our study results could contribute to the individualised general risk assessment to guide decisions about the need for newborns with prenatally diagnosed CPM to be delivered at specialised centers.

scholarly journals Screening for Primary Aldosteronism: Implications of an Increased Plasma Aldosterone/Renin Ratio

2002 ◽  
Vol 48 (11) ◽  
pp. 1919-1923 ◽  
Author(s):  
Gary L Schwartz ◽  
Arlene B Chapman ◽  
Eric Boerwinkle ◽  
Robert M Kisabeth ◽  
Stephen T Turner
Keyword(s):  
Black Women ◽  
Primary Aldosteronism ◽  
Predictive Value ◽  
White Women ◽  
Plasma Renin ◽  
Plasma Aldosterone ◽  
Plasma Aldosterone Concentration ◽  
Sample Distribution ◽  
Patients At Risk ◽  
Sensitivity Specificity

Abstract Background: The value of the ratio of plasma aldosterone concentration (aldosterone) to plasma renin activity (renin) to identify patients at risk for primary aldosteronism is controversial. We determined the sensitivity, specificity, and predictive value of the ratio to identify combinations of renin and aldosterone compatible with primary aldosteronism. Methods: The ratio was calculated in 505 adults with essential hypertension (143 black women, 82 black men, 122 white women, and 158 white men). We used a conventional cutpoint for an increased ratio (i.e., 20 mL/dL · h). The primary combination of renin and aldosterone considered compatible with primary aldosteronism was increased aldosterone for the concomitant renin, defined as aldosterone in the highest quartile predicted by linear regression on renin. Renin was considered low if it was in the lowest quartile of the sample distribution. Results: The sensitivity of the ratio to identify individuals with increased aldosterone for the concomitant renin was 66% (80% in blacks and 56% in whites; P = 0.009), and the specificity of the ratio was 67% (46% in blacks and 84% in whites; P &lt;0.0001). In 36% of instances of an increased ratio, it was a measure of low renin alone without increased aldosterone for renin (32% in blacks and 45% in whites; P = 0.072). The positive predictive value of the ratio to identify individuals with increased aldosterone for the concomitant renin was 34% (49% in whites and 27% in blacks; P &lt;0.002). Conclusion: The aldosterone/renin ratio lacks sensitivity and specificity and has only a modest predictive value for combinations of renin and aldosterone that are compatible with primary aldosteronism.

Reassessment of the Predictive Value of the Postural Stimulation Test in Primary Aldosteronism

1991 ◽  
Vol 4 (9) ◽  
pp. 786-791 ◽  
Author(s):  
Rosita G. Fontes ◽  
Claudio E. Kater ◽  
Edward G. Biglieri ◽  
Ilan Irony
Keyword(s):  
Primary Aldosteronism ◽  
Predictive Value ◽  
Stimulation Test

TEM observation of iron oxide pillars in montmorillonite

1990 ◽  
Vol 48 (4) ◽  
pp. 882-883
Author(s):  
H. Mori ◽  
Y. Murata ◽  
H. Yoneyama ◽  
H. Fujita
Keyword(s):  
Aqueous Solution ◽  
Iron Oxide ◽  
Fine Particles ◽  
Aqueous Suspension ◽  
Volume Ratio ◽  
Exchange Capacity ◽  
Nano Composites ◽  
Pillared Montmorillonite ◽  
Topographic Features ◽  
Transmission Electron

Recently, a new sort of nano-composites has been prepared by incorporating such fine particles as metal oxide microcrystallites and organic polymers into the interlayer space of montmorillonite. Owing to their extremely large specific surface area, the nano-composites are finding wide application[1∼3]. However, the topographic features of the microstructures have not been elucidated as yet In the present work, the microstructures of iron oxide-pillared montmorillonite have been investigated by high-resolution transmission electron microscopy.Iron oxide-pillared montmorillonite was prepared through the procedure essentially the same as that reported by Yamanaka et al. Firstly, 0.125 M aqueous solution of trinuclear acetato-hydroxo iron(III) nitrate, [Fe3(OCOCH3)7 OH.2H2O]NO3, was prepared and then the solution was mixed with an aqueous suspension of 1 wt% clay by continuously stirring at 308 K. The final volume ratio of the latter aqueous solution to the former was 0.4. The clay used was sodium montmorillonite (Kunimine Industrial Co.), having a cation exchange capacity of 100 mequiv/100g. The montmorillonite in the mixed suspension was then centrifuged, followed by washing with deionized water. The washed samples were spread on glass plates, air dried, and then annealed at 673 K for 72 ks in air. The resultant film products were approximately 20 μm in thickness and brown in color.

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