The Origin of Microglia Determines the Content of Exosomes and Biological Function

2018 ◽  
Author(s):  
Adriana-Natalia Murgoci ◽  
Khalil Mallah ◽  
Soulaimane Aboulouard ◽  
Christophe Lefebvre ◽  
Firas Kobeissy ◽  
...  
Keyword(s):  
Biological Function

Sobre el concepto de función en biología. Historia y problemas recientes

2010 ◽  
Vol 16 ◽  
Author(s):  
Andrés L. Jaume
Keyword(s):  
Biological Function ◽  
Mechanistic Explanation ◽  
Functional Explanation ◽  
Function Concept ◽  
Philosophical Thinking ◽  
Systemic Theory ◽  
Points Of View

RESUMENEl presente artículo analiza las diferentes teorías que sobre el concepto de función se han vertido en los últimos cuarenta años y sus problemas. Respecto de los dos grandes enfoques (histórico-etiológico y sistémico) se sostiene que el primero, pese a su hegemonía histórica, presenta considerables dificultades y que la reflexión actual se centra cada vez más en la perspectiva sistémica. Esta última puede enfrentarse mejor a los diversos problemas que genera el concepto de función biológica y es siempre preferible.PALABRAS CLAVEFUNCIÓN BIOLÓGICA, FUNCIÓN SISTéMICA, EXPLICACIÓN FUNCIONAL, EXPLICACIÓN BASADA EN MECANISMOS, TELEOLOGíAABSTRACTThis paper analyzes the different theories on biological function and the problems they brought up over the last forty years. Concerning the two most important points of view on functions (aetiological theory and systemic theory) I hold that the aetiological theory, despite its historical hegemony, presents substantial difficulties and that the present philosophical thinking is centred on systemic theories. Systemic theories are capable of solving the various problems generated by the biological function concept which is preferable.KEYWORDSBIOLOGICAL FUNCTION, SySTEMIC FUNCTION, FUNCTIONAL EXPLANATION, MECHANISTIC EXPLANATION TELEOLOGY

The Progress of the Biological Function of Rap Signaling in Nervous System

2012 ◽  
Vol 28 (7) ◽  
pp. 593
Author(s):  
Zongyong ZHANG ◽  
Bin LI ◽  
Jianfeng LIU ◽  
Li SU
Keyword(s):  
Nervous System ◽  
Biological Function

The Origin of Microglia Determines the Content of Exosomes and Biological Function

2018 ◽  
Author(s):  
Adriana-Natalia Murgoci ◽  
Khalil Mallah ◽  
Soulaimane Aboulouard ◽  
Christophe Lefebvre ◽  
Firas Kobeissy ◽  
...  
Keyword(s):  
Biological Function

A Survey for Predicting Enzyme Family Classes Using Machine Learning Methods

2019 ◽  
Vol 20 (5) ◽  
pp. 540-550 ◽  
Author(s):  
Jiu-Xin Tan ◽  
Hao Lv ◽  
Fang Wang ◽  
Fu-Ying Dao ◽  
Wei Chen ◽  
...  
Keyword(s):  
Machine Learning ◽  
Catalytic Mechanism ◽  
Biological Function ◽  
Learning Methods ◽  
Biochemical Processes ◽  
Machine Learning Methods ◽  
Enzyme Family ◽  
The Family ◽  
Speed Up ◽  
Family Classification

Enzymes are proteins that act as biological catalysts to speed up cellular biochemical processes. According to their main Enzyme Commission (EC) numbers, enzymes are divided into six categories: EC-1: oxidoreductase; EC-2: transferase; EC-3: hydrolase; EC-4: lyase; EC-5: isomerase and EC-6: synthetase. Different enzymes have different biological functions and acting objects. Therefore, knowing which family an enzyme belongs to can help infer its catalytic mechanism and provide information about the relevant biological function. With the large amount of protein sequences influxing into databanks in the post-genomics age, the annotation of the family for an enzyme is very important. Since the experimental methods are cost ineffective, bioinformatics tool will be a great help for accurately classifying the family of the enzymes. In this review, we summarized the application of machine learning methods in the prediction of enzyme family from different aspects. We hope that this review will provide insights and inspirations for the researches on enzyme family classification.

Sign in / Sign up

Export Citation Format

Share Document