Lessons Learned from Stabilization Initiatives in Afghanistan: A Systematic Review of Existing Research

2017 ◽  
Author(s):  
Radha Iyengar ◽  
Jacob N. Shapiro ◽  
Stephen Hegarty
Keyword(s):  
Systematic Review ◽  
Lessons Learned

scholarly journals Lessons learned from drug trials in neurofibromatosis: A systematic review

2021 ◽  
pp. 104281
Author(s):  
Britt A.E. Dhaenens ◽  
Rosalie E. Ferner ◽  
D. Gareth Evans ◽  
Guenter Heimann ◽  
Cornelia Potratz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lessons Learned ◽  
Drug Trials

scholarly journals Application of US EPA IRIS systematic review methods to the health effects of phthalates: Lessons learned and path forward

2020 ◽  
Vol 145 ◽  
pp. 105820 ◽  
Author(s):  
Elizabeth G. Radke ◽  
Erin E. Yost ◽  
Nicolas Roth ◽  
Sheela Sathyanarayana ◽  
Paul Whaley
Keyword(s):  
Systematic Review ◽  
Health Effects ◽  
Lessons Learned ◽  
Systematic Review Methods ◽  
Us Epa

scholarly journals Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned With the Zebrafish Embryotoxicity Test

2019 ◽  
Vol 171 (1) ◽  
pp. 56-68
Author(s):  
Martin L Stephens ◽  
Sevcan Gül Akgün-Ölmez ◽  
Sebastian Hoffmann ◽  
Rob de Vries ◽  
Burkhard Flick ◽  
...  
Keyword(s):  
Systematic Review ◽  
Developmental Toxicity ◽  
Test Methods ◽  
Lessons Learned ◽  
Hazard Identification ◽  
Test Method ◽  
Main Study ◽  
Systematic Review Methodology ◽  
Method Performance ◽  
Toxicological Test

AbstractSystematic review methodology is a means of addressing specific questions through structured, consistent, and transparent examinations of the relevant scientific evidence. This methodology has been used to advantage in clinical medicine, and is being adapted for use in other disciplines. Although some applications to toxicology have been explored, especially for hazard identification, the present preparatory study is, to our knowledge, the first attempt to adapt it to the assessment of toxicological test methods. As our test case, we chose the zebrafish embryotoxicity test (ZET) for developmental toxicity and its mammalian counterpart, the standard mammalian prenatal development toxicity study, focusing the review on how well the ZET predicts the presence or absence of chemical-induced prenatal developmental toxicity observed in mammalian studies. An interdisciplinary team prepared a systematic review protocol and adjusted it throughout this piloting phase, where needed. The final protocol was registered and will guide the main study (systematic review), which will execute the protocol to comprehensively answer the review question. The goal of this preparatory study was to translate systematic review methodology to the assessment of toxicological test method performance. Consequently, it focused on the methodological issues encountered, whereas the main study will report substantive findings. These relate to numerous systematic review steps, but primarily to searching and selecting the evidence. Applying the lessons learned to these challenges can improve not only our main study, but may also be helpful to others seeking to use systematic review methodology to compare toxicological test methods. We conclude with a series of recommendations that, if adopted, would help improve the quality of the published literature, and make conducting systematic reviews of toxicological studies faster and easier over time.

scholarly journals Telemedicine in Neurosurgery: Lessons Learned from a Systematic Review of the Literature for the COVID-19 Era and Beyond

Neurosurgery ◽  
2020 ◽  
Vol 88 (1) ◽  
pp. E1-E12 ◽  
Author(s):  
Daniel G Eichberg ◽  
Gregory W Basil ◽  
Long Di ◽  
Ashish H Shah ◽  
Evan M Luther ◽  
...  
Keyword(s):  
Systematic Review ◽  
The United States ◽  
Lessons Learned ◽  
Patient Encounter ◽  
Review Of The Literature ◽  
Face To Face ◽  
Regulatory Changes ◽  
Foreign Countries ◽  
Neurosurgical Patients ◽  
Barriers And Challenges

Abstract BACKGROUND Evolving requirements for patient and physician safety and rapid regulatory changes have stimulated interest in neurosurgical telemedicine in the COVID-19 era. OBJECTIVE To conduct a systematic literature review investigating treatment of neurosurgical patients via telemedicine, and to evaluate barriers and challenges. Additionally, we review recent regulatory changes that affect telemedicine in neurosurgery, and our institution's initial experience. METHODS A systematic review was performed including all studies investigating success regarding treatment of neurosurgical patients via telemedicine. We reviewed our department's outpatient clinic billing records after telemedicine was implemented from 3/23/2020 to 4/6/2020 and reviewed modifier 95 inclusion to determine the number of face-to-face and telemedicine visits, as well as breakdown of weekly telemedicine clinic visits by subspecialty. RESULTS A total of 52 studies (25 prospective and 27 retrospective) with 45 801 patients were analyzed. A total of 13 studies were conducted in the United States and 39 in foreign countries. Patient management was successful via telemedicine in 99.6% of cases. Telemedicine visits failed in 162 cases, 81.5% of which were due to technology failure, and 18.5% of which were due to patients requiring further face-to-face evaluation or treatment. A total of 16 studies compared telemedicine encounters to alternative patient encounter mediums; telemedicine was equivalent or superior in 15 studies. From 3/23/2020 to 4/6/2020, our department had 122 telemedicine visits (65.9%) and 63 face-to-face visits (34.1%). About 94.3% of telemedicine visits were billed using face-to-face procedural codes. CONCLUSION Neurosurgical telemedicine encounters appear promising in resource-scarce times, such as during global pandemics.

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