Integration of Amygdalar Urocortin 1 and Endocannabinoid Signaling on the Modulation of Ethanol Reinstatement and Preference

2017 ◽  
Author(s):  
Aaron Dirks
Keyword(s):  
Urocortin 1

Stressors affect urocortin 1 and urocortin 2 gene expression in rat spleen: The role of glucocorticoids

2019 ◽  
Vol 336 ◽  
pp. 577030
Author(s):  
Andrej Tillinger ◽  
Alexandra Padová ◽  
Boris Mravec ◽  
Aleksandra Tomova
Keyword(s):  
Gene Expression ◽  
Urocortin 1

Differences in the urocortin 1 system between long-sleep and short-sleep mice

2007 ◽  
Vol 0 (0) ◽  
pp. 070629195945001-???
Author(s):  
Victoria F. Turek ◽  
Beth Bennett ◽  
Andrey E. Ryabinin
Keyword(s):  
Short Sleep ◽  
Long Sleep ◽  
Urocortin 1

LPS inhibits fasted plasma ghrelin levels in rats: role of IL-1 and PGs and functional implications

2006 ◽  
Vol 291 (4) ◽  
pp. G611-G620 ◽  
Author(s):  
Lixin Wang ◽  
Nicole R. Basa ◽  
Almaas Shaikh ◽  
Andrew Luckey ◽  
David Heber ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Gastric Emptying ◽  
Food Intake ◽  
Intravenous Injection ◽  
Plasma Levels ◽  
Inhibitory Action ◽  
Functional Implications ◽  
Urocortin 1 ◽  
Fasted Rats

LPS injected intraperitoneally decreases fasted plasma levels of ghrelin at 3 h postinjection in rats. We characterized the inhibitory action of LPS on plasma ghrelin and whether exogenous ghrelin restores LPS-induced suppression of food intake and gastric emptying in fasted rats. Plasma ghrelin and insulin and blood glucose were measured after intraperitoneal injection of LPS, intravenous injection of IL-1β and urocortin 1, and in response to LPS under conditions of blockade of IL-1 or CRF receptors by subcutaneous injection of IL-1 receptor antagonist (IL-1Ra) or astressin B, respectively, and prostaglandin (PG) synthesis by intraperitoneal indomethacin. Food intake and gastric emptying were measured after intravenous injection of ghrelin at 5 h postintraperitoneal LPS injection. LPS inhibited the elevated fasted plasma ghrelin levels by 47.6 ± 4.9%, 58.9 ± 3.3%, 74.4 ± 2.7%, and 48.9 ± 8.7% at 2, 3, 5, and 7 h postinjection, respectively, and values returned to preinjection levels at 24 h. Insulin levels were negatively correlated to those of ghrelin, whereas there was no significant correlation between glucose and ghrelin. IL-1Ra and indomethacin prevented the first 3-h decline in ghrelin levels induced by LPS, whereas astressin B did not. IL-1β inhibited plasma ghrelin levels, whereas urocortin 1 had no influence. Ghrelin injected intravenously prevented an LPS-induced 87% reduction of gastric emptying and 61% reduction of food intake. These data showed that IL-1 and PG pathways are part of the early mechanisms by which LPS suppresses fasted plasma ghrelin and that exogenous ghrelin can normalize LPS-induced-altered digestive functions.

Activation of urocortin 1 and ghrelin signaling in the basolateral amygdala induces anxiogenesis

Neuroreport ◽  
2013 ◽  
pp. 1 ◽  
Author(s):  
Paul J. Currie ◽  
Lindsey M. Schuette ◽  
Shelby E.R. Wauson ◽  
William N. Voss ◽  
Mark J. Angeles
Keyword(s):  
Basolateral Amygdala ◽  
Urocortin 1

scholarly journals Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0147375 ◽  
Author(s):  
Eva Calderón-Sánchez ◽  
Ignacio Díaz ◽  
Antonio Ordóñez ◽  
Tarik Smani
Keyword(s):  
Cd40 Ligand ◽  
Urocortin 1

Su1913 Intracerebroventricular Urocortin 1-Induced Anorexia Involves Peripheral α2 Adrenergic Receptor Mediated Inhibition of Ghrelin in Rats: Prevention by Rikkunshito

2014 ◽  
Vol 146 (5) ◽  
pp. S-499-S-500
Author(s):  
Koji Yakabi ◽  
Mitsuko Ochiai ◽  
Shoki Ro ◽  
Eriko Hosomi ◽  
Kenjiro Hayashi ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Urocortin 1

Urocortin 1-containing neurons in the human Edinger-Westphal nucleus

Neuroscience ◽  
2005 ◽  
Vol 134 (4) ◽  
pp. 1317-1323 ◽  
Author(s):  
A.E. Ryabinin ◽  
N.O. Tsivkovskaia ◽  
S.A. Ryabinin
Keyword(s):  
Urocortin 1 ◽  
Edinger Westphal Nucleus

Sa1859 Expression of Urocortin 1 and Corticotropin-Releasing Factor Receptors in Gastrointestinal Tract of Patients With Crohn's Disease

2016 ◽  
Vol 150 (4) ◽  
pp. S383
Author(s):  
Burcu Hasdemir ◽  
Elizabeth Garnett ◽  
Gregory Victorino ◽  
Nina Holland ◽  
Mel Heyman ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Gastrointestinal Tract ◽  
Crohn's Disease ◽  
Corticotropin Releasing Factor ◽  
Urocortin 1
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