Random Inspections and Periodic Reviews: Optimal Dynamic Monitoring

2017 ◽  
Author(s):  
Felipe Varas ◽  
Ivan Marinovic
Keyword(s):  
Dynamic Monitoring ◽  
Optimal Dynamic

Random Inspections and Periodic Reviews: Optimal Dynamic Monitoring

2020 ◽  
Vol 87 (6) ◽  
pp. 2893-2937 ◽  
Author(s):  
Felipe Varas ◽  
Iván Marinovic ◽  
Andrzej Skrzypacz
Keyword(s):  
Moral Hazard ◽  
Hazard Rate ◽  
Dynamic Monitoring ◽  
Main Concern ◽  
Optimal Monitoring ◽  
Optimal Dynamic

Abstract We study the design of monitoring in dynamic settings with moral hazard. An agent (e.g. a firm) benefits from reputation for quality, and a principal (e.g. a regulator) can learn the agent’s quality via costly inspections. Monitoring plays two roles: an incentive role, because outcomes of inspections affect agent’s reputation, and an informational role because the principal directly values the information. We characterize the optimal monitoring policy inducing full effort. When information is the principal’s main concern, optimal monitoring is deterministic with periodic reviews. When incentive provision is the main concern, optimal monitoring is random with a constant hazard rate.

scholarly journals Monitoring with Limited Information

2020 ◽  
Author(s):  
Dan Andrei Iancu ◽  
Nikolaos Trichakis ◽  
Do Young Yoon
Keyword(s):  
Static Problem ◽  
Dynamic Monitoring ◽  
Optimization Approach ◽  
Limited Information ◽  
Worst Case ◽  
Transplant Patients ◽  
Optimal Monitoring ◽  
State Dependent ◽  
The Status ◽  
Optimal Dynamic

We consider a system with an evolving state that can be stopped at any time by a decision maker (DM), yielding a state-dependent reward. The DM does not observe the state except for a limited number of monitoring times, which he must choose, in conjunction with a suitable stopping policy, to maximize his reward. Dealing with these types of stopping problems, which arise in a variety of applications from healthcare to finance, often requires excessive amounts of data for calibration purposes and prohibitive computational resources. To overcome these challenges, we propose a robust optimization approach, whereby adaptive uncertainty sets capture the information acquired through monitoring. We consider two versions of the problem—static and dynamic—depending on how the monitoring times are chosen. We show that, under certain conditions, the same worst-case reward is achievable under either static or dynamic monitoring. This allows recovering the optimal dynamic monitoring policy by resolving static versions of the problem. We discuss cases when the static problem becomes tractable and highlight conditions when monitoring at equidistant times is optimal. Lastly, we showcase our framework in the context of a healthcare problem (monitoring heart-transplant patients for cardiac allograft vasculopathy), where we design optimal monitoring policies that substantially improve over the status quo recommendations. This paper was accepted by Chung Piaw Teo, optimization.

The dynamic monitoring of benefit/risk balance in the system of pharmacological control

2018 ◽  
Vol 26 (6) ◽  
Author(s):  
Milchakov K. S. ◽  
◽  
Kosagovskaya I. I. ◽  
Kobiyatskaya E. E. ◽  
Rosalieva Yu. Yu. ◽  
...  
Keyword(s):  
Dynamic Monitoring ◽  
Risk Balance ◽  
Pharmacological Control

Innovative approaches to operational treatment of women of reproductive eligibility age with hyperplastic processes of the endometrium

2016 ◽  
pp. 41-45
Author(s):  
V.N. Goncharenko ◽  
Keyword(s):  
Endometrial Hyperplasia ◽  
Histopathological Examination ◽  
Intraoperative Complications ◽  
Transvaginal Ultrasound ◽  
Treatment Algorithm ◽  
Hormone Treatment ◽  
Endometrial Ablation ◽  
Reproductive Age ◽  
Dynamic Monitoring ◽  
Atypical Form

The aim of the study: was improvement of results of surgical treatment of patients of reproductive age eligibility with hyperplastic processes of endometrium (HPE) through the introduction of individualized treatment algorithm with the use of monopolar radio wave and hysteroscopic endometrial ablation. Materials and methods. The study included 62 women with non-atypical form of hyperplasia of the endometrium who were treated at the Center of General gynecology of the clinical hospital «Feofania», gynecological Department at the city maternity hospital № 3 of Kyiv. Depending on the age group, nature of the pathological process and method of treatment is randomized, the distribution of women according to groups: group 1 – 41 women's reproductive eligibility age netipichnaya forms of endometrial hyperplasia (PHEBA and KGEB), who were subjected to hysteroscopic monopolar endometrial ablation; group 2 – 21 female reproductive eligibility age netipichnaya forms of endometrial hyperplasia (PHEBA and KGEB), which was held radiowave ablation of the endometrium (RHAE). In the 1st group the age of patients ranged from 42 to 54 years, mean age was 49.9±4.7 years. In the 2nd group the age of patients ranged from 41 to 53 years, mean age of 51.6±4.3 years. Results. A comparative analysis of the techniques for hysteroscopic monopolar ablation and RHEE showed the fact that for RHEE used local anesthesia, while carrying out hysteroscopic monopolar ablation was necessary intravenous anesthesia. The duration of the hysteroscopic monopolar endometrial ablation was 28.6±5.5 min, RAE – according to the standard method – 44.3±0.3 min. When performing hysteroscopic monopolar endometrial ablation in 2 patients (3.7%) patients observed the signs of intravasation of fluid, increased blood pressure and tachycardia. This syndrome was successfully docked, but in the future, women have conducted a thorough examination. When you run RHAE intraoperative complications have been identified. Conclusion. 1. Women with netipichnaya forms of endometrial hyperplasia eligibility and late reproductive age who do not have reproductive plans as an alternative to hysterectomy, in the presence of contraindications or ineffectiveness of hormone treatment may be recommended or radiowave monopolar hysteroscopic ablation of the endometrium. 2. Monopolar hysteroscopic endometrial ablation is indicated for women with netipichnaya forms of endometrial hyperplasia, can be used in the presence of submucous form of uterine fibroids, postoperative scars on the uterus, but in the absence of adenomyosis II–III degree. The effectiveness of monopolar hysteroscopic endometrial ablation in women with non-atypical form of hyperplasia of the endometrium is 87.8%. 3. Women after endometrial ablation should be under observation for two years. The method of choice for dynamic monitoring of the condition of the uterus in women who underwent endometrial ablation is transvaginal ultrasound which should be performed after 1, 3, 6, 12 and 24 months of follow up. 4. In case of recurrence of hyperplastic process of the endometrium (bleeding, thickening of the M-mode echo according to the ultrasound) shows a hysteroscopy with a mandatory histopathological examination and verification of the diagnosis. Key words: endometrial hyperplasia, women eligibility age, women of reproductive age, ablation of the endometrium.

DYNAMIC MONITORING IN ANTI-CRISIS MANAGEMENT OF STATE ECONOMIC SECURITY

2017 ◽  
pp. 108-111
Author(s):  
Ruslan Savenko
Keyword(s):  
Social Security ◽  
Crisis Management ◽  
Management System ◽  
Economic Security ◽  
Dynamic Monitoring ◽  
Systematic Observation ◽  
Management Decisions ◽  
Ecological Economic ◽  
Efficient Management ◽  
Research Institute

UDC 6585:330   Savenko Ruslan, doctor of sciences, professor. Poltava national technical Yuri Kondratyuk university. Dynamic monitoring in anti-crisis management of state economic security. This paper aimed at the problem of improvement the management system of economic security of natural use objects on a regional level using the organized digital dynamic monitoring for informational provision and justifying the options of efficient management decisions of operative and strategic importance by criteria of ecological, economic and social security. Monitoring of the regional (territorial) natural objects provides constant systematic observation of the processes that take place inside of a “region-state” system and at world’s natural resources market. It needed to create the informational database for efficient management of a nature-use system. We suggest plan of making the scientific and research institute in PoltNTU for conducting investigations based on continuous informational monitoring. Keywords: monitoring, management system, ecological-economic-social security, natural use resources, algorithm, scientific and research institute, management decisions.

Challenges in the differential diagnosis of multiple endocrine neoplasia syndrome type 1 with isolated family hyperparathyroidism

2020 ◽  
Vol 98 (3) ◽  
pp. 218-225
Author(s):  
J. A. Krupinova ◽  
N. G. Mokrysheva ◽  
N. Y. Kalinchenko ◽  
A. K. Eremkina ◽  
A. N. Polyakov ◽  
...  
Keyword(s):  
Multiple Endocrine Neoplasia ◽  
Molecular Genetic ◽  
Pancreatic Neuroendocrine Tumor ◽  
Family Type ◽  
Dynamic Monitoring ◽  
Heterozygous Mutation ◽  
Molecular Genetic Study ◽  
Men 1 ◽  
Endocrine Neoplasia

Multiple endocrine neoplasia type 1 (MEN-1) is the most common cause of the hereditary type of primary hyperparathyroidism (PHPT). If a family type of PHPT is suspected, a dynamic monitoring of patients and their close relatives should be carried out throughout their lives. We present a clinical case of a family in which four members of a pedigree were diagnosed with familial isolated hyperparathyroidism (FIHP). The diagnosis was changed to MEN-1, because it appeared that one of the patients had pancreatic neuroendocrine tumor. Molecular genetic study of MEN1 by direct by means of Sanger sequencing revealed that six family members had a new heterozygous mutation in exon 9: s. 1252 G> T p. D418Y.

SYSTEM FOR DYNAMIC MONITORING AND WARNING IN CASE OF ECOLOGICAL RISK FOR SURFACE WATERS

2014 ◽  
Vol 13 (7) ◽  
pp. 1757-1764
Author(s):  
Constantin Vilcu ◽  
Gheorghe Voicu ◽  
Gigel Paraschiv ◽  
Emilia Sofia Manole ◽  
Carol Lehr ◽  
...  
Keyword(s):  
Ecological Risk ◽  
Surface Waters ◽  
Dynamic Monitoring

Dynamic monitoring of changes in medical and demographic indicators in the Republic of Sakha (Yakutia) from 1998 to 2018

2020 ◽  
pp. 33-36
Keyword(s):  
Mortality Rate ◽  
Population Growth ◽  
Russian Federation ◽  
Rural Population ◽  
Urban Population ◽  
Birth Rate ◽  
Dynamic Monitoring ◽  
Demographic Indicators ◽  
The Russian Federation ◽  
The Republic

We studied the medical and demographic indicators in the Republic of Sakha (Yakutia) for the last 20 years (1998–2018). A decrease in the population by 4,7 % (р<0,01) was revealed in the Russian Federation in the period 1998–2008, 3,4 % decrease, followed by its growth by 2,8 % (р<0,01); a decrease in the number of rural population in the republic and an increase in the urban population were observed. By the beginning of 2019, in comparison with the 2003 data, an increase in the population by 1.9% (р<0,01), a decrease in the number of able-bodied people in the Republic of Sakha (Yakutia) at the beginning of 2019, as compared to 1998, were revealed, by 8,2 %, in the Russian Federation – by 4,7 % (р<0,01). In the Republic of Sakha (Yakutia) the birth rate remains high, the mortality rate is relatively low, and the natural population growth is maintained.

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