The Effect of Theta Variable Before and After of Screening Process to Every Changes of Price and Volume of Jakarta Composite Index, Application of TSR Method

2015 ◽  
Author(s):  
Hidajat Sofyan Widjaja
Keyword(s):  
Composite Index ◽  
Screening Process ◽  
Before And After

Using a mobile application to improve pediatric presumptive TB identification in western Kenya

2021 ◽  
Vol 25 (6) ◽  
pp. 468-474
Author(s):  
D. Szkwarko ◽  
J. A. Amisi ◽  
D. Peterson ◽  
S. Burudi ◽  
P. Angala ◽  
...  
Keyword(s):  
Early Recognition ◽  
Screening Process ◽  
Case Register ◽  
Western Kenya ◽  
Primary Care Clinics ◽  
Before And After ◽  
Community Health Volunteer ◽  
Pediatric Tb ◽  
Mobile Screening ◽  
Tb Mobile

BACKGROUND: Early recognition of TB symptoms in children is critical in order to link children to appropriate testing and treatment. Healthcare workers (HCWs) in high TB burden countries are often overburdened with competing clinical priorities, leading to incomplete presumptive TB screening. We assessed if implementing a community health volunteer (CHV) led presumptive pediatric TB mobile android application (PPTBMAPP) in pediatric outpatient, primary care clinics in western Kenya would be feasible, appropriate, and effective.METHODS: We used a mixed-methods participatory, iterative approach to design and implement the PPTBMAPP during a 6-month period. We compared the proportion of children identified in presumptive TB and active TB disease registers out of all patients before and after the implementation of the intervention.RESULTS: Of the 1787 children aged ≤15 years screened using the PPTBMAPP, 376 (21%) met the criteria for presumptive TB. There was a statistically significant increase in the proportion of children to all patients in the presumptive TB registers (97/908, 10.7% vs. 160/989, 16.2%; P = 0.0005), and a trend towards an increase in the proportion of children to all patients in the TB case register (17/117, 14.5% vs. 15/83, 18.1%; P = 0.5). HCWs interviewed commented that the application sped up the presumptive TB screening process.CONCLUSION: Our CHV-led mobile screening intervention significantly increased presumptive TB notification. HCWs reported that the mobile screening intervention was feasible, appropriate, and effective.

scholarly journals A model-guided pipeline for drug cardiotoxicity screening with human stem-cell derived cardiomyocytes

2021 ◽  
Author(s):  
Alexander P. Clark ◽  
Siyu Wei ◽  
Trine Krogh-Madsen ◽  
David J. Christini
Keyword(s):  
Stem Cell ◽  
High Risk ◽  
High Sensitivity ◽  
Drug Approval ◽  
Screening Process ◽  
Hek 293 ◽  
Before And After ◽  
Drug Approval Process ◽  
Therapeutic Compounds

ABSTRACTNew therapeutic compounds go through a preclinical drug cardiotoxicity screening process that is overly conservative and provides limited mechanistic insight, leading to the misclassification of potentially beneficial drugs as proarrhythmic. There is a need to develop a screening paradigm that maintains this high sensitivity, while ensuring non-cardiotoxic compounds pass this phase of the drug approval process. In this study, we develop an in vitro-in silico pipeline using human induced stem-cell derived cardiomyocytes (iPSC-CMs) to address this problem. The pipeline includes a model-guided optimization that produces a voltage-clamp (VC) protocol to determine drug block of seven cardiac ion channels. Such VC data, along with action potential (AP) recordings, were acquired from iPSC-CMs before and after treatment with a control solution or a low-, intermediate-, or high-risk drug. We identified significant AP prolongation (a proarrhythmia indicator) in two high-risk drugs and, from the VC data, determined strong ion channel blocks that led to the AP changes. The VC data also uncovered an undocumented funny current (If) block by quinine, which we confirmed with experiments using a HEK-293 expression line. We present a new approach to cardiotoxicity screening that simultaneously evaluates proarrhythmia risk (e.g. AP prolongation) and mechanism (e.g. channel block) from iPSC-CMs.

Opening the Floodgates: The Implications of Increasing Platform Openness in Crowdfunding

2017 ◽  
Vol 32 (4) ◽  
pp. 344-360 ◽  
Author(s):  
Michael Wessel ◽  
Ferdinand Thies ◽  
Alexander Benlian
Keyword(s):  
Policy Change ◽  
Natural Experiment ◽  
Third Party ◽  
Success Rates ◽  
Policy Changes ◽  
Screening Process ◽  
Ripple Effects ◽  
Before And After ◽  
Platform Ecosystems ◽  
And Control

Managing platform ecosystems requires providers to govern the permeability of platform boundaries in order to strike a balance between openness and control. But is it worthwhile for platform providers to conduct screening processes for third-party offerings, or should they rather apply a laissez-faire approach and let the market determine winners and losers? In this study, we compare the market conditions on Kickstarter, one of the world's largest crowdfunding platforms, before and after a policy change that relaxed the previously stringent screening process for new campaigns. By analyzing over 230,000 crowdfunding campaigns with a combined funding of over $1.9 billion that cover a 4-year period around the policy change, we find that increasing platform openness was a double-edged sword for the platform's ecosystem. While Kickstarter's revenue from commissions surged after the policy change due to an increase in the number of campaigns available on the platform, funding conditions for project creators and backers deteriorated. Project creators have to cope with lower success rates and an intensified competition due to a growing disproportion of backers to campaigns, while backers face higher uncertainties as project creators invest less in reducing information asymmetries. Our evidence from this natural experiment therefore suggests that increasing platform openness for third-party offerings can destabilize a platform's ecosystem. We thus extend the literature on platform openness and on the implications of policy changes on platform ecosystems. Our findings also provide practical insights for different platform stakeholders into possible “ripple effects” that are triggered when policy changes alter platform openness.

scholarly journals ADAKAH PENGARUH FREE FLOAT TERHADAP PELAKU PASAR SAHAM DI INDONESIA?

2019 ◽  
Vol 21 (1) ◽  
pp. 39-46
Author(s):  
PUTRI MUTIRA
Keyword(s):  
Stock Prices ◽  
Stock Price ◽  
Stock Exchange ◽  
Composite Index ◽  
High Price ◽  
Percentage Increase ◽  
Price Changes ◽  
Average Value ◽  
Before And After ◽  
Additional Reference

Indonesian Stock Exchange has released free float adjustment index on November 2018 and composite index declined about 3,2%. Free Float will be an additional reference for the exchange in compiling an index which previously used market capitalization and total transaction value. This study examines the average daily price changes of LQ45 stocks within 60 days before and after the announcement. The daily closing price changes are calculated as a percentage increase or decrease of stock prices according to the previous day, then, the average value is calculated for all the trading days. There are differences in the average stock price changes 60 days before and after the announcement date. After dropped, the price rebound and make a new higher high price two days after the announcement. Bank BCA, Bank Mandiri, Bank BRI, Bank BNI, Astra International and Telkom are companies which increase the weight of the free float meanwhile Unilever and H.M Sampoerna were the opposite.

scholarly journals Abnormal Return and Trading Volume Activity Before and After Presidential Election 2019 ( Study on LQ-45 stock on February-July 2019)

2019 ◽  
Vol 34 (2) ◽  
Author(s):  
C H Asta Nugraha ◽  
Suroto Suroto
Keyword(s):  
Capital Market ◽  
Presidential Election ◽  
Abnormal Return ◽  
Trading Volume ◽  
Composite Index ◽  
T Test ◽  
Volume Activity ◽  
Paired Samples ◽  
Significant Difference ◽  
Before And After

<p>This study aims to find out the empirical evidence of Indonesia capital market investors’ reaction toward presidential election 2019. The population in this study is the companies’ stocks which are included in the LQ-45 index during this study. The data used is secondary data in the form of LQ-45 stocks and daily Composite index three days before and three days after the event. By implementing the one sample t-test and paired samples t-test, the result shows that there is a positive and significant abnormal return around the event especially on the third day (t+3) after the event.  Moreover, there is an insignificant difference in the average of negative abnormal return and significant difference on the average of negative trading volume activity, before and after the presidential election 2019.</p><p><strong>Keywords:</strong> Capital Market, Event Study, Abnormal Return, Trading Volume Activity, Investors’ Reactions</p><p class="Default"><em>Penelitian ini bertujuan untuk menemukan bukti empiris reaksi investor pasar modal Indonesia terhadap peristiwa pemilihan presiden 2019. Populasi penelitian ini adalah saham-saham perusahaan yang konsisten tergabung dalam indeks LQ-45 selama periode penelitian. Data yang digunakan adalah data sekunder berupa harga saham LQ-45 dan IHSG harian tiga hari sebelum dan tiga hari setelah peristiwa. Uji statistik yang digunakan untuk menguji hipotesis adalah one sample t-test dan  paired samples t-test. Hasil yang diperoleh menunjukkan terdapat abnormal return positif dan signifikan di sekitar  peristiwa terutama pada hari ke-3 (t+3) setelah peristiwa. Selain itu, terdapat perbedaan rata-rata abnormal retrun negatif tidak signifikan dan terdapat perbedaan rata-rata trading volume activity negatif yang signifikan antara sebelum dan setelah peristiwa pemilihan presiden 2019. </em></p><p><strong><em>Kata Kunci</em></strong><em>: Pasar Modal, Studi Peristiwa, </em>Abnormal Return, Trading Volume Activity, <em>Reaksi Investor</em></p>

EIA SCREENING IN DENMARK: A NEW REGULATORY INSTRUMENT?

2005 ◽  
Vol 07 (01) ◽  
pp. 35-49 ◽  
Author(s):  
ESKILD HOLM NIELSEN ◽  
PER CHRISTENSEN ◽  
LONE KØRNØV
Keyword(s):  
Environmental Impact ◽  
Impact Assessment ◽  
Cost Effective ◽  
Environmental Benefits ◽  
Screening Process ◽  
Administrative Process ◽  
Environmental Criteria ◽  
Before And After ◽  
Effective Instrument ◽  
Filtering Procedure

Environmental Impact Assessment (EIA) is the process by which the effects that proposed projects are likely to have are assessed with respect to a number of environmental criteria. Screening is an activity carried out in advance of an EIA to determine whether, in fact, it is necessary to undertake a full assessment. In that sense screening has become not only an administrative filtering procedure but also effectively a kind of regulation. Since the implementation of the Directive in 1999, counties (county councils) in Denmark have screened around 2000 projects annually. Approximately 3 percent of the decisions arising from screening lead to a "full EIA". This article is based on a study of 98 documented screening decisions combined with interviews with developers and their consultants as well as county officials for each project. Herein, we analyse both the number of modifications to projects made due to the screening process and also how radical or significant the modifications were. EIA regulation meant that approximately 45 percent of the projects were modified. Around half of these modifications were actually made before the administrative process even started. The mere fact that screening exists functions as an eye-opener to developers and consultants. In general, the nature of changes made before and after submission of the application was similar. They covered basically minor changes. Examining the assessments made during screening more closely, we conclude that there is still far to go in order to make the assessment broader and more holistic in accordance with the ambitions set out in the EIA Directive. Among other things, this goes for the assessment of cumulative and potential impacts. On the basis of the evaluation, we also conclude that screening is effectively a regulatory instrument in its own right. Moreover, it seems to be a cost-effective instrument in the sense that, without incurring much administrative expense, it potentially results in environmental benefits.

scholarly journals Qualitative study of Ebola screening at ports of entry to the UK

2018 ◽  
Vol 3 (3) ◽  
pp. e000788 ◽  
Author(s):  
Joanna May Kesten ◽  
Suzanne Audrey ◽  
Maya Holding ◽  
Caroline Coope ◽  
Nick Young ◽  
...  
Keyword(s):  
Qualitative Study ◽  
Focus Groups ◽  
Ebola Virus ◽  
Virus Disease ◽  
Individual Risk ◽  
Screening Process ◽  
Before And After ◽  
Qualitative Focus Groups ◽  
Negative Impacts ◽  
The Uk

IntroductionIn response to the 2013–2016 West African outbreak of the Ebola virus disease (EVD), Public Health England introduced enhanced screening at major UK ports of entry. Our aim was to explore screeners’ and screened travellers’ perceptions of screening as part of an evaluation of the screening programme.MethodsWe undertook qualitative focus groups and semistructured interviews with screeners and travellers who had returned from affected countries before and after the introduction of screening in England. The study was conducted in two airports: one international rail terminal and one military airport. Research topic guides explored perceptions of the purpose and implementation of the process, potential improvements and reactions to screening. The data were analysed using the framework method.ResultsTwenty-four screeners participated in 4 focus groups (one for each port of entry) and 23 travellers participated in interviews. Three themes are presented: ‘Context’, ‘Screeners’ experience of the programme’ and ‘Screening purpose and experiences’. The programme was implemented rapidly, refined over time and adapted to individual ports. Screeners reported diverse experiences of screening including negative impacts on their normal roles, difficult interactions with passengers and pressure to identify positive EVD cases. Screening was considered unlikely to identify individuals with symptoms of EVD, and some participants suggested it was driven by political concerns rather than empirical evidence. The screening process was valued for its provision of information and reassurance.ConclusionThis qualitative study found that the UK EVD screening process was perceived to be acceptable to assess individual risk and provide information and advice to travellers. Future programmes should have clear objectives and streamlined processes to minimise disruption, tailored to the nature of the threat and developed with the needs of humanitarian workers as well as general travellers in mind.

Analisis Perbedaan Abnormal Return Dan Laba Perusahaan Sebelum Dan Sesudah Share Split Atau Reverse Share Split

2012 ◽  
Vol 4 (2) ◽  
pp. 1-23
Author(s):  
Amelinda Timothea Winata ◽  
Rosita Suryaningsih
Keyword(s):  
Abnormal Return ◽  
Sampling Method ◽  
Composite Index ◽  
Secondary Data ◽  
Share Price ◽  
Net Income ◽  
Financial Reports ◽  
Significant Difference ◽  
Before And After ◽  
The Difference

The purpose of this research was to analyze the difference of abnormal return and net income before and after share split or reverse share split. Abnormal return and net income are important to investor because it indicated the corporate performance and useful for investor’s decision making. The samples used in this research were 61 companies for variable of abnormal return and 59 companies for variable of net income. These samples were the companies that listed in Indonesia Share Exchange (IDX) for period 2003-2010 and meet the criteria sampling of this study. The samples were determined based on purposive sampling method. Data that used in this research was secondary data, such as share price, Indonesia Composite Index (ICI), and financial reports. The method used for analysis was paired sample t-test. The results of this research are (1) there is significant difference between abnormal return before and after share split, (2) there is no significant difference between net income before and after share split, (3) there is significant difference between abnormal return before and after reverse share split, and (4) there is no significant difference between net income before and after reverse share split. Keywords: share split, reverse share split, abnormal return, net income.

scholarly journals Virtual Reality Therapy: an Effective Treatment for the Fear of Public Speaking

1998 ◽  
Vol 3 (3) ◽  
pp. 1-6 ◽  
Author(s):  
Max M. North ◽  
Sarah M. North ◽  
Joseph R. Coble
Keyword(s):  
Virtual Reality ◽  
Public Speaking ◽  
Comparison Group ◽  
Reality Therapy ◽  
Screening Process ◽  
Virtual Reality Therapy ◽  
Treatment Conditions ◽  
Before And After ◽  
Fear Of Public Speaking ◽  
Visualization Techniques

The major goal of this research was to investigate the efficacy of virtual reality therapy (VRT) in the treatment of the fear of public speaking. After an extensive two-stage screening process, sixteen subjects were selected from the pool. They were assigned to two treatment conditions: VRT (N=8) and comparison group (N=8). Fourteen subjects completed the study. The VRT group was exposed to the virtual reality public speaking scene while the comparison group was exposed to a trivial virtual reality scene and guided by the experimenters to manage their phobia either by using visualization techniques or selfexposure to the situation they feared. The VRT and comparison group sessions were conducted on an individual basis over a five week period. Two assessment measures were used in this study. The first measure used was the Attitude Towards Public Speaking (ATPS) Questionnaire. The second measure used was the eleven-point Subjective Units of Disturbance (SUD) scale. These measurements assessed the anxiety, avoidance, attitudes and disturbance associated with their fear of public speaking before and after treatments. In addition, objective measures such as heart rate was collected in each stage of the treatment. Significant differences between the six subjects who completed the VRT sessions and comparison group were found on all measures. The VRT group showed significant improvement after five weeks of treatment. The comparison group did not show any meaningful changes. The authors concluded that VRT was successful in reducing the fear of the public speaking.

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