scholarly journals Prediction of Therapeutic Doses of Antipsychotic Drugs as Dopamine D2 Receptor Antagonists. Approach Based on Receptor Occupancy Theory.

1993 ◽  
Vol 8 (2) ◽  
pp. 247-261 ◽  
Author(s):  
Yasuhiko YAMADA ◽  
Yasufumi SAWADA ◽  
Risa TAKAYANAGI ◽  
Kiyomi ITO ◽  
Kouichi NAKAMURA ◽  
...  
Keyword(s):  
Antipsychotic Drugs ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Occupancy ◽  
Receptor Antagonists ◽  
Dopamine D2 ◽  
Therapeutic Doses

Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer

Life Sciences ◽  
2006 ◽  
Vol 78 (26) ◽  
pp. 3007-3012 ◽  
Author(s):  
Vanessa N. Barth ◽  
Eyassu Chernet ◽  
Laura J. Martin ◽  
Anne B. Need ◽  
Karen S. Rash ◽  
...  
Keyword(s):  
Antipsychotic Drugs ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Occupancy ◽  
Dopamine D2 ◽  
Dopamine D2 Receptor Occupancy

Predicting Dopamine D2 Receptor Occupancy From Plasma Levels of Antipsychotic Drugs

2011 ◽  
Vol 31 (3) ◽  
pp. 318-325 ◽  
Author(s):  
Hiroyuki Uchida ◽  
Hiroyoshi Takeuchi ◽  
Ariel Graff-Guerrero ◽  
Takefumi Suzuki ◽  
Koichiro Watanabe ◽  
...  
Keyword(s):  
Plasma Levels ◽  
Antipsychotic Drugs ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Occupancy ◽  
Dopamine D2 ◽  
Dopamine D2 Receptor Occupancy

scholarly journals A QM protein–ligand investigation of antipsychotic drugs with the dopamine D2 Receptor (D2R)

2017 ◽  
Vol 36 (10) ◽  
pp. 2668-2677 ◽  
Author(s):  
Ramin Ekhteiari Salmas ◽  
Yusuf Serhat Is ◽  
Serdar Durdagi ◽  
Matthias Stein ◽  
Mine Yurtsever
Keyword(s):  
Antipsychotic Drugs ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Dopamine D2

Dopamine D2 Receptor Occupancy as a Predictor of Catalepsy in Rats: A Pharmacokinetic-Pharmacodynamic Modeling Approach

2014 ◽  
Vol 31 (10) ◽  
pp. 2605-2617 ◽  
Author(s):  
Martin Johnson ◽  
Magdalena Kozielska ◽  
Venkatesh Pilla Reddy ◽  
An Vermeulen ◽  
Hugh A. Barton ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Occupancy ◽  
Pharmacodynamic Modeling ◽  
Modeling Approach ◽  
Dopamine D2 ◽  
Dopamine D2 Receptor Occupancy

Poster #217 PREDICTING DOPAMINE D2 RECEPTOR OCCUPANCY FOLLOWING ANTIPSYCHOTIC DOSE REDUCTION: A PILOTPETSTUDY

2012 ◽  
Vol 136 ◽  
pp. S359
Author(s):  
Hiroyuki Uchida ◽  
Robert R. Bies ◽  
Takefumi Suzuki ◽  
Ariel Graff-Guerrero ◽  
Bruce G. Pollock ◽  
...  
Keyword(s):  
Dose Reduction ◽  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Occupancy ◽  
Dopamine D2 ◽  
Dopamine D2 Receptor Occupancy

Poster #218 DOPAMINE D2 RECEPTOR OCCUPANCY AND COGNITION IN SCHIZOPHRENIA: ANALYSIS OF THE CATIE DATA

2012 ◽  
Vol 136 ◽  
pp. S359
Author(s):  
Hiroyuki Uchida ◽  
Hitoshi Sakurai ◽  
Robert R. Bies ◽  
Scott Stroup ◽  
Richard S.E. Keefe ◽  
...  
Keyword(s):  
Dopamine D2 Receptor ◽  
D2 Receptor ◽  
Receptor Occupancy ◽  
Dopamine D2 ◽  
Dopamine D2 Receptor Occupancy
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