Five Novel Single Nucleotide Polymorphisms in the EPHX1 Gene Encoding Microsomal Epoxide Hydrolase

2003 ◽  
Vol 18 (2) ◽  
pp. 150-153 ◽  
Author(s):  
Kisho Shiseki ◽  
Masaya Itoda ◽  
Yoshiro Saito ◽  
Yukiko Nakajima ◽  
Keiko Maekawa ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Epoxide Hydrolase ◽  
Microsomal Epoxide Hydrolase ◽  
Nucleotide Polymorphisms ◽  
Gene Encoding ◽  
Single Nucleotide

scholarly journals Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia

2002 ◽  
Vol 10 (9) ◽  
pp. 569-573 ◽  
Author(s):  
Jaana Laasanen ◽  
Eeva-Liisa Romppanen ◽  
Mikko Hiltunen ◽  
Seppo Helisalmi ◽  
Arto Mannermaa ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Epoxide Hydrolase ◽  
Microsomal Epoxide Hydrolase ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals Association of Single-Nucleotide Polymorphisms in DC-SIGN with Nasopharyngeal Carcinoma Susceptibility

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Sisi Li ◽  
Zhifang Lu ◽  
Mengwei Yao ◽  
Sisi Ning ◽  
Yuan Wu ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Nasopharyngeal Carcinoma ◽  
Single Nucleotide Polymorphisms ◽  
Odds Ratio ◽  
Chinese Population ◽  
Smoking History ◽  
Intercellular Adhesion Molecule ◽  
Nucleotide Polymorphisms ◽  
Gene Encoding ◽  
Single Nucleotide

The aim of this study was to explore potential relationships of four single-nucleotide polymorphisms (SNPs) in the gene encoding dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) with risk of nasopharyngeal carcinoma (NPC). The DC-SIGN SNPs rs7252229, rs4804803, rs2287886, and rs735240 were genotyped in 477 unrelated NPC patients and 561 cancer-free controls. At rs7252229, risk of NPC was significantly lower in individuals with GC (odds ratio [OR] 0.076, 95% confidence interval [CI] 0.008–0.690), GG (OR 0.056, 95%CI 0.006–0.487), or GC + GG (OR 0.059, 95%CI 0.007–0.515) than in individuals with the CC genotype, after adjusting for age, gender, smoking history, and EBV-VCA-IgA status. At rs4804803, risk of NPC was significantly higher in individuals with the genotype GG than in those with the genotype AA (adjusted OR 9.038, 95%CI 1.708–47.822). At rs735240, risk of NPC did not change significantly with genotypes AG, GG, or AG + GG after adjusting for age, gender, and smoking history. However, when data were also adjusted for EBV-VCA-IgA status, three genotypes emerged as associated with significantly higher risk of NPC than the AA genotype: AG (OR 2.976, 95%CI 1.123–7.888), GG (OR 3.314, 95%CI 1.274–8.622), or GG + AG (OR 3.191, 95%CI 1.237–8.230). Our results suggest that DC-SIGN SNPs rs7252229, rs4804803, and rs735240 may influence NPC risk in the Chinese population. The mechanisms mediating this risk require a further study.

scholarly journals Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes

Diabetologia ◽  
2005 ◽  
Vol 48 (7) ◽  
pp. 1315-1322 ◽  
Author(s):  
A. Kanazawa ◽  
Y. Kawamura ◽  
A. Sekine ◽  
A. Iida ◽  
T. Tsunoda ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Gene Encoding ◽  
Single Nucleotide

scholarly journals Single nucleotide polymorphisms in partial sequences of the gene encoding the large sub-units of ADP-glucose pyrophosphorylase within a representative collection of 10 Musa genotypes

2014 ◽  
Vol 17 (3) ◽  
pp. 137-147
Author(s):  
Muhilan Mahendhiran ◽  
Jorge Humberto Ramirez-Prado ◽  
Rosa Maria Escobedo-Gracia Medrano ◽  
Blondy Canto-Canché ◽  
Miguel Tzec-Simá ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Gene Encoding ◽  
Single Nucleotide ◽  
Adp Glucose Pyrophosphorylase
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