scholarly journals Efficacy of Bronchial Wash Cytology and its Correlation with Histopathology in Diagnosis of Lung Carcinoma in a Tertiary Care Hospital

2021 ◽  
Vol 8 (2) ◽  
pp. A45-49
Author(s):  
Shilpa Tomar ◽  
Brijesh Thakur ◽  
Krishna Dubey ◽  
Priyanka Gulati
Keyword(s):  
Lung Cancer ◽  
Cell Carcinoma ◽  
Lung Carcinoma ◽  
Tertiary Care Hospital ◽  
Diagnostic Yield ◽  
Tertiary Care ◽  
Bronchial Biopsy ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Bronchial Wash

Introduction: Cytological evaluation is an important, usually initial diagnostic modality in patients with suspected malignant lung masses. Bronchoscopic washing, bronchoalveolar lavage, bronchial brushing and fine needle aspirations may complement tissue biopsies in the diagnosis of lung cancer. This study was undertaken to compare the efficacy of bronchial wash cytology and to correlate it with histopathology in diagnosis of suspected cases of lung cancer at a tertiary care hospital. Material and methods: Bronchial washings and bronchial biopsy were collected from total 60 clinically suspected cases of carcinoma lung. Bronchial washing smears were stained with MGG and H&E stain and were categorized as unequivocally positive / unequivocally negative for malignancy and atypical (equivocal for diagnosis). Biopsy sections were examined for histopathological diagnosis. Results: Cytomorphologically, 30 cases were reported as positive for malignancy, 28 cases were negative for malignancy and 02 cases were atypical. On histopathology, lung carcinoma was diagnosed in 48 patients out of them 35 cases were of squamous cell carcinoma, 7 cases were of small cell carcinoma and 6 were of large cell carcinoma. Conclusion: Maximum diagnostic yield can be obtained by combining biopsy with cytological procedures of washing rather alone.

scholarly journals Usefulness of Fiber-optic Bronchoscopy in the Diagnosis of Pulmonary Diseases in Diabetic Patients: Experience in a Tertiary Care Hospital

2016 ◽  
Vol 6 (1) ◽  
pp. 18-21
Author(s):  
Jamal Uddin Ahmed ◽  
Md Delwar Hossain ◽  
Muhammad Abdur Rahim ◽  
AKM Musa
Keyword(s):  
Cell Carcinoma ◽  
Fiber Optic ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Invasive Procedure ◽  
Inflammatory Lesion ◽  
Bronchial Biopsy ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Normal Finding

Background: Fiber-optic bronchoscopy (FOB) is an invasive procedure performed to identify possible endobronchial lesions. Diabetic patients often present with non-resolving pneumonia and collapse, many of whom are elderly and smoker; thus always giving rise to the suspicion of malignancy.Methods: This observational study was performed from March 2009 to August 2013 in the Department of Internal Medicine and Pulmonology of BIRDEM General Hospital, Dhaka, Bangladesh; a 500 bedded tertiary care hospital dealing mostly with diabetic patients.Results: Out of 160 diabetic patients 126 (78.7%) were male, 34 (21.3%) were female. Mean age of the patients was – 57.2 ±10.8 years. The indications of bronchoscopy were collapse (38, 23.8%), non-resolving consolidation (55, 34.4%), mass lesion (38, 23.8%), hemoptysis (10, 6.2%) and others (19, 11.8%). Findings in the bronchoscopy were mitotic lesion (56, 35.0%), inflammatory lesion (50, 31.3%) and normal finding (54, 33.8%). Among 56 cases of mitotic lesion, bronchial biopsy was taken in 48 (85.7%) cases. Histopathology reports of bronchial biopsy were squamous cell carcinoma (18, 37.5%), large cell carcinoma (11, 22.9%), adenocarcinoma (7, 14.6%), small cell carcinoma (5, 10.4%), inflammatory lesion (4, 8.3%) and normal finding (3, 6.3%). Among 38 cases of collapse, mitotic lesion was found in 24 (63.2%) cases. Among 55 (100%) cases of non-resolving consolidation, mitotic lesion was found in 18 (32.5%), inflammation in 23 (41.8%) and normal findings in 14 (25.5%) cases.Conclusion: Bronchoscopy is an useful method to detect any endobronchial lesion in suspected cases of collapse or non-resolving pneumonia in diabetic patients and it can be the choice of investigation in non-resolving pneumonia.Birdem Med J 2016; 6(1): 18-21

scholarly journals Prevalence of type and etiology of lung cancer among the patients presented to a tertiary care hospital at central Kerala: a descriptive study

2018 ◽  
Vol 6 (3) ◽  
pp. 834
Author(s):  
Vadakkan Devassy Thomas ◽  
Binila Jose ◽  
Davis Kizhakkepeedika Rennis
Keyword(s):  
Lung Cancer ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Male Dominance ◽  
Care Hospital ◽  
The Right

Background: Lung cancer remains the most common cause of premature mortality in men in developing countries. This study was aimed to evaluate the type and etiological factors of lung cancer in patients presented to a tertiary care hospital of central Kerala.Methods: A retrospective descriptive study was conducted in patients who were diagnosed as lung cancer. The medical records of such patients were reviewed. The data such as age, gender, etiological risk factors and type of lung cancer were collected. Patients with incomplete reports or repeated tests, or histopathological findings were negative for lung cancers were excluded from the study.Results: Total 228 patients were included in the study with age of 64.71± 9.75. The male (198) and female (30) ratio was 6.6:1, indicated the male dominance. Among the histological types, the squamous cell carcinoma was 29% (68/228) found as the most prevalent type which is followed by adenocarcinoma 26 % (61/228). The right side (132/228) lobe was the major segment than the left side (91/228). Similarly, incidence in the central region (128/228) was more than the peripheral region (69/228). Among the right side, the upper lobe was dominant when compared to the lower or middle lobe. The lower left lobe incidence was found in 47/228 cases. Among the total, 188 cases were tobacco smokers while the remaining were nonsmokers.Conclusions: Squamous cell carcinoma with right side upper lobe of lung was prevalent among the lung cancer cases. Tobacco smoking was found to be the major etiological factor.

Diagnostic yield of Archer FusionPlex PanHeme and solid panels: two-year experience from a pediatric tertiary care hospital

2021 ◽  
Vol 132 ◽  
pp. S39-S40
Author(s):  
Kathleen Schieffer ◽  
Eileen Stonerock ◽  
Vijayakumar Jayaraman ◽  
Heather Jenkins ◽  
Tim Peterson ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Diagnostic Yield ◽  
Tertiary Care ◽  
Care Hospital

Clinico-pathological profile of ovarian cysts in a tertiary care hospital

2017 ◽  
Vol 6 (10) ◽  
pp. 4642 ◽  
Author(s):  
Sairem Mangolnganbi Chanu ◽  
Biswajit Dey ◽  
Vandana Raphael ◽  
Subrat Panda ◽  
Yookarin Khonglah
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Serous Cystadenoma ◽  
Mature Cystic Teratoma ◽  
Ovarian Cysts ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
North East

Background: Ovarian cystic neoplasms are common in gynaecological practice. These may pose diagnostic difficulty to the pathologists. This study was conducted to analyse the clinical and histological profile of ovarian cystic neoplasms.Methods: This is a retrospective study done from January 2016 to April 2017 in a tertiary care hospital in North East India. All the patients, who were clinically and radiologically diagnosed as ovarian cysts, which had histopathological confirmation were included in the study. Data including the age, parity, clinical symptoms, laterality and histopathological findings were analysed.Results: A total of 101 patients operated for ovarian cysts in the study period were analysed. The most common clinical presentation was lower abdominal pain. There were 11 (10.9%) malignant cases, 4 (4%) were intermediate grade and borderline in nature, and 85 (84.1%) cases were benign in nature. There was 1 (1%) case of metastasis to ovary. Mature cystic teratoma was most common (20.8%) histopathological diagnosis. The second most common cyst was serous cystadenoma (19.8%).Conclusion: Ovarian cysts are commonly encountered in gynaecological practice and equally encountered by the pathologists. Most commonly found ovarian cysts were mature cystic teratoma followed by serous cystadenoma.

scholarly journals Lung cancer profile at tertiary care hospital, South Tamil Nadu

2019 ◽  
Vol 4 (4) ◽  
pp. 245-251
Author(s):  
Prem Ananth P ◽  
◽  
R Gnanasekaran ◽  
N Nagarajan ◽  
Deiveegan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Tamil Nadu ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital

scholarly journals Clinicopathological profile of squamous cell carcinoma presenting in Tertiary Care Hospital, Karachi.

2020 ◽  
Vol 27 (05) ◽  
pp. 939-943
Author(s):  
Sameera Asif ◽  
Summera Kanwal ◽  
Tahera Ayub ◽  
Zafar Abbas ◽  
Batool Vazir ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Buccal Mucosa ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Stage Iv ◽  
Stage Ii ◽  
Stage Iii ◽  
Care Hospital

Objectives: Oral Squamous cell carcinoma (OSCC) is the most common malignant tumor of the oral cavity. The study was done with the aim to determine the clinical pattern of OSCC seen in tertiary care hospital of Karachi, Pakistan. The frequency of neck metastasis in different staging of squamous cell carcinoma was also recorded. Study Design: Retrospective study. Setting: Department of Oral & Maxillofacial Surgery Liaquat College of Medicine and Dentistry. Period: June 2013- July 2016. Material & Methods: It included 35 males and 25 females which presented with different sites and stage of squamous cell carcinoma. Clinically patients were staged as stage I, stage II, stage III and stage IV and comprised of 3, 8, 30 & 19 patients respectively. Patients presented with cancer of buccal mucosa (31 patients), retromolar region (12 patients), maxillary alveolus (8 patients), tongue (2 patients), floor of mouth (4 patients) & lip (3 patients). Right side was most common, 48 patients as compare to left side, 12 patients while lip cancers was in upper lip in all patients including commissure. Results: Total 60 patients were included in the study with the male to female ratio of 1.4:1. No significant association was seen between age and gender of the patient (p-value 0.933). Majority of patients were male involving buccal mucosa (51.67%) as the most frequently involved site followed by retromolar area (20%) and tongue (13.3%). Mean age of patients included in the study was 50.87 ± 5.53. Conclusion: Most of the cases of OSCC were seen in older patients with increased number of cases involving buccal mucosa as their primary site. Majority of the tumors were classified as stage III followed by Stage IV, Stage II and stage 1 respectively.

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