scholarly journals Diagnostic utility of immunohistochemical expression of HE4 in Epithelial Ovarian Neoplasm

2019 ◽  
Vol 6 (11) ◽  
pp. A567-571
Author(s):  
Begum Afrin Nahar ◽  
◽  
Rama Saha ◽  
Chhanda Das ◽  
Gourishankar Kamilya ◽  
...  
Keyword(s):  
Ovarian Neoplasm ◽  
Diagnostic Utility ◽  
Immunohistochemical Expression ◽  
Epithelial Ovarian Neoplasm

scholarly journals Diagnostic utility of GATA3 immunohistochemical expression in urothelial carcinoma

2019 ◽  
Vol 62 (2) ◽  
pp. 244 ◽  
Author(s):  
Chanchal Rana ◽  
Harshita Agarwal ◽  
Suresh Babu ◽  
Madhu Kumar ◽  
Atin Singhai ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Diagnostic Utility ◽  
Immunohistochemical Expression

scholarly journals Immunohistochemical expression of human epididymis 4 in ovarian malignancy

2019 ◽  
Vol 7 (12) ◽  
pp. 4493
Author(s):  
Begum Afrin Nahar ◽  
Rama Saha ◽  
Chhanda Das ◽  
Gourishankar Kamilya
Keyword(s):  
Ovarian Cancer ◽  
Ovarian Neoplasm ◽  
Serous Carcinoma ◽  
Ovarian Cancer Cells ◽  
High Grade ◽  
Ovarian Malignancy ◽  
Endometrioid Carcinoma ◽  
Immunohistochemical Expression ◽  
Human Epididymis ◽  
Cancer Support

Background: Ovarian malignancies has the highest mortality rate among all gynaecological malignancies. Surface epithelial tumors form two thirds of all ovarian neoplasm and 90% of all ovarian cancers are surface epithelial carcinomas. Mortality in case of ovarian malignancy is high due to late diagnosis. Early and accurate diagnosis can improve the case specific management. HE4 (Human Epididymis Protein 4) which is proved to be overexpressed in the ovarian cancer cells, is considered a new biomarker for ovarian cancer diagnosis which helps in early diagnosis and patient management. Aims and objectives of the study was to evaluate the immunohistochemical expression of HE4 in various ovarian malignancies.Methods: It was a cross sectional, prospective, single institution-based study, conducted in the department of Pathology in collaboration with the Department of Gynaecology and Obstetrics, from December 2016 to January 2019 in institution. A total 74 ovarian malignancies were selected for this study.Results: Serous carcinoma was the most common ovarian malignancy followed by endometrioid carcinoma. Highest percentage of expression of HE4 was seen in high grade serous cancer and malignant endometrioid tumor.Conclusions: HE4 was highly expressed in malignant ovarian tumour especially serous and endometrioid carcinoma and can be used as an important biomarker for malignant ovarian neoplasm. Expression in high grade ovarian serous cancer support its prognostic value also.

Diagnostic utility of imprint cytology of ovarian neoplasm: A cyto-histological comparison

2020 ◽  
Vol 5 (3) ◽  
pp. 209-212
Author(s):  
Kuruvilla P Chacko ◽  
◽  
Reily Ann Ivan ◽  
Blessy Mary Thomas ◽  
◽  
...  
Keyword(s):  
Ovarian Neoplasm ◽  
Diagnostic Utility ◽  
Imprint Cytology

CYP1A1 Gene Polymorphism and Risk of Epithelial Ovarian Neoplasm

2002 ◽  
Vol 86 (2) ◽  
pp. 124-128 ◽  
Author(s):  
Dilek Aktas ◽  
Inci Guney ◽  
Mehmet Alikasifoglu ◽  
Kunter Yüce ◽  
Ergul Tuncbilek ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Ovarian Neoplasm ◽  
Epithelial Ovarian Neoplasm ◽  
Cyp1a1 Gene
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