scholarly journals Phytochemical Analysis and Antibacterial Activities of Boswellia Ovalifoliolata

2017 ◽  
Vol 6 (7) ◽  
pp. 589-598
Keyword(s):  
Antibacterial Activities ◽  
Phytochemical Analysis ◽  
Boswellia Ovalifoliolata

scholarly journals FTIR PHYTOCHEMICAL FINGERPRINTING AND ANTIOXIDANT ANLYSES OF SELECTED INDOOR NON-FLOWERING INDOOR PLANTS AND THEIR INDUSTRIAL IMPORTANCE

2016 ◽  
Vol 8 (4) ◽  
pp. 37
Author(s):  
Jayaprada Rao Chunduri ◽  
Hetwi R. Shah
Keyword(s):  
Reducing Power ◽  
Antibiotic Sensitivity ◽  
Antibacterial Activities ◽  
Phytochemical Analysis ◽  
Zone Of Inhibition ◽  
Ph Indicator ◽  
Sensitivity Testing ◽  
Indoor Plants ◽  
The Rich ◽  
High Concentrations

Objective: phytochemical screening and antioxidant activity analyses of selected indoor plants and to evaluate commercial applications.Methods: Qualitative and quantitative phytochemical analyses of alcoholic and aquatic crude extracts of leaves of selected non-flowering indoor plants were assessed using standard protocols and later compared with FTIR analyses. Antioxidant and antibacterial activities of the extracts were studiedResults: Phytochemical analysis of polar solvent extractions of the four selected plants Pedilanthus tithymaloides, Cordyline terminalis, Tradescantia zebrine and Rhoeo discolou. Indicated the presence of tannins in all four varieties terpenoids in 3, flavonols, phytosterols and phenols in two plants, followed by alkaloids. The phytochemical analyses were supported by FTIR reports. Quantitative studies indicated variations in flavonol, tannin and phenols concentrations among the four species. High concentrations of Total flavonols (P. tithymaloides) and Tannins (C. terminalis) were observed. C. terminalis extract showed comparatively highest reducing power followed by R. discolour and P. tithymaloides extracts. Antibiotic Sensitivity Testing indicated P. tithymaloides showed a maximum zone of inhibition compared to R. discolor. C. terminalis plant leaf extract showed a faint zone of inhibition against E. fecalis while others couldnot. Intense colors of C. terminalis and T. zebrine plants could be used as a natural dye as well as pH indicator. Conclusion: The rich concentrations of the tannins from non-flowering indoor plants could be the future option of dyes and dyeing industry as natural colorants as well as pH indicators. These plants were rich sources of phytochemicals (phenols, flavonols, tannins, and phytosterols), with antioxidant and antibacterial activity.

scholarly journals Evaluation of Antibacterial Activities of Fractions from Ethanol-Extracted Residues of Piper guineense Leaves on Gram Negative Clinical Isolate

2021 ◽  
Vol 10 (9) ◽  
pp. 8-17
Author(s):  
Tharcitus Chilaka Onwudiwe Prince Chiazor Unekwe ◽  
Kingsley Chimsorom Chilaka Malachy Ifeanyi Obi
Keyword(s):  
Plant Material ◽  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Modern Society ◽  
Antibacterial Activities ◽  
Phytochemical Analysis ◽  
Piper Guineense ◽  
Standard Drug ◽  
Gram Negative ◽  
Antibacterial Screening

The problem of drug resistance to orthodox antimicrobial agents has remained a setback in the treatment of bacterial infections in the modern society. Adverse effects, coupled with scarcity and high cost of orthodox drugs have necessitated interest in the search, development and use of antibacterial agents from plant origin. Piper guineense is claimed in traditional medicine as a remedy for gram negative organism-transmitted infections. The leaves of Piper guineense plant was collected, washed, dried at room temperature and pulverized. The plant material was extracted with 80% ethanol. The ethanol-extracted residue was subjected to fractionation. Seventeen fractions were obtained, and were pooled together based on their Rf values into five pooled-fractions labeled: PF-1, PF-2, PF-3, PF-4, PF-5. Both the ethanol and fraction extracts were subjected to phytochemical analysis, preliminary antibacterial screening, minimum inhibitory and minimum bactericidal concentrations determination using both clinical isolates and type culture organisms. The yield of ethanol-extracted residue was low (21.08g) when compared to the amount of pulverized plant material (500g). Phytochemical analysis revealed the presence of flavonoids, alkaloids and terpenoids in all the extracts. The extracts produced statistically significant lower zone of inhibition (p<0.05) when compared with the standard drug (amoxicillin), it also demonstrated activity against test organisms used in the study. The findings of this study demonstrated that ethanol leaf extract of Piper guineense possess antibacterial activities, therefore justifies the traditional claim of the plant.

scholarly journals Phytochemical Analysis and Biological Investigation of Nepeta juncea Benth. Different Extracts

Plants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 646 ◽  
Author(s):  
Majid Sharifi-Rad ◽  
Francesco Epifano ◽  
Serena Fiorito ◽  
José M. Álvarez-Suarez
Keyword(s):  
Inhibitory Concentration ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Dry Weight ◽  
Antibacterial Activities ◽  
Gas Chromatography Mass Spectrometry ◽  
Phytochemical Analysis ◽  
Biological Investigation ◽  
First Time ◽  
Dpph Radical Scavenging

This study was carried out to screen the amount and the classes of secondary metabolites and to evaluate the antioxidant, cytotoxic, antifungal, and antibacterial activities of the methanolic, ethanolic, and water extracts of the roots, leaves, and flowers of Nepeta juncea Benth. The results show that the highest total phenol (69.54 ± 0.31 mg gallic acid equivalents (GAE)/g dry weight), total flavonoid (41.37 ± 0.17 mg quercetin equivalents (QE)/g dry weight), anthocyanin (6.52 ± 0.21 mg cyanidin/100 g dry weight), and tannin (47.36 ± 0.33 mg catechin/g dry weight) concentrations were recorded in the methanolic extract of the leaves of N. juncea. The gas chromatography–mass spectrometry (GC–MS) analysis of the extracts showed that 1,8-cineole, 4aα-7α-7aα-nepetalactone, β-pinene, terpinen-4-ol, and α-terpineol were the major compounds, respectively. The best 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and ferric-reducing antioxidant, cytotoxic, antifungal, and antibacterial activities were observed for the methanolic extract of the leaves. For the two latter activities, the best activity was revealed on Staphylococcus aureus, Bacillus cereus, and Candida albicans. The minimum inhibitory concentration (MIC) values for the antimicrobial of the methanolic extract from the leaves were in the range of 25–100 µg/mL, whereas the minimum bactericidal concentration (MBC) values were in the range of 50–200 µg/mL. The results reported herein show that, for the first time in the literature, N. juncea is a remarkable source of antioxidant, antifungal, and antibacterial compounds.

Phytochemical Analysis, Antioxidant and Antibacterial Activities of Two Traditionally Used Indian Medicinal Plants

2017 ◽  
Vol 4 (3) ◽  
pp. 1-11
Author(s):  
Rajamanickam Karthika ◽  
Packirisamy Meenatchi ◽  
Ramalingam Sundaram ◽  
Ayyakkannu Purushothaman
Keyword(s):  
Medicinal Plants ◽  
Antibacterial Activities ◽  
Phytochemical Analysis ◽  
Indian Medicinal Plants

scholarly journals Tristemma hirtumand Five Other Cameroonian Edible Plants with Weak or No Antibacterial Effects Modulate the Activities of Antibiotics against Gram-Negative Multidrug-Resistant Phenotypes

2018 ◽  
Vol 2018 ◽  
pp. 1-12
Author(s):  
Gaëlle S. Nguenang ◽  
Armelle T. Mbaveng ◽  
Aimé G. Fankam ◽  
Hermione T. Manekeng ◽  
Paul Nayim ◽  
...  
Keyword(s):  
Antibacterial Activities ◽  
Multidrug Resistant ◽  
Phytochemical Analysis ◽  
Edible Plants ◽  
Phytochemical Screening ◽  
Antibacterial Effects ◽  
Gram Negative ◽  
Microdilution Method ◽  
Raphia Hookeri

In order to contribute to the fight against infectious diseases, thein vitroantibacterial activity and the antibiotic-potentiating effects ofTristemma hirtumand five other Cameroonian edible plants have been evaluated against Gram-negative multidrug-resistant (MDR) phenotypes. The microdilution method was used to evaluate the bacterial susceptibility of the extracts and their combination to common antibiotics. The phytochemical screening of the extracts was carried out according to standard methods. Phytochemical analysis of the extracts revealed the presence of alkaloids, triterpenes, steroids, and polyphenols, including flavonoids in most of the tested extracts. The entire tested extracts showed moderate (512 μg/mL ≤ MIC ≤ 2048 μg/mL) to weak (MIC > 2048 μg/mL) antibacterial activities against the tested bacteria. Furthermore, extracts of leaf ofTristemma hirtumand pericarpsofRaphia hookeri(at their MIC/2 and MIC/4) strongly potentiated the activities of all antibiotics used in the study, especially those of chloramphenicol (CHL), ciprofloxacin (CIP), kanamycin (KAN), and tetracycline (TET) against 70% (7/10) to 100% (10/10) of the tested MDR bacteria, with the modulating factors ranging from 2 to 128. The results of this study suggest that extracts from leaves ofTristemma hirtumand pericarps ofRaphia hookerican be sources of plant-derived products with antibiotic modifying activity.

scholarly journals Phytochemical and Antibacterial Profile of Some Liquid Herbal Preparations Sold in Abia State, South-Eastern Nigeria

2020 ◽  
pp. 58-65
Author(s):  
Pipi O.G. ◽  
Keyword(s):  
Antibacterial Activities ◽  
Phytochemical Analysis ◽  
Bacterial Isolates ◽  
Bacterial Strains ◽  
Secondary Products ◽  
Herbal Preparations ◽  
Ph Values ◽  
Bioactive Properties ◽  
Single Compound ◽  
Phytochemical Profile

The use of liquid herbal preparations (LHPs) in the treatment and management of human diseases has long been practiced before the advent of chemotherapy. The beneficial medicinal effects of liquid herbal preparations materials typically result from the secondary products present in the liquid herbal preparations although, it is usually not attributed to a single compound but a combination of the metabolites. This study was carried out to evaluate the antibacterial and phytochemical profile of some liquid herbal preparations in selected markets of Abia State using biochemical and microbiological assay. Preliminary qualitative phytochemical analysis of the liquid herbal preparations inferred the presence of alkaloids (30%), quinones (6%), saponins (7%), flavonoids (19%), glycosides (17%) and tannins (22%). The antibacterial activities of 20 LHPs with bioactive properties against 3 tested clinical bacterial isolates; Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, from hospital samples was evaluated using agar well diffusion methods. Inhibitory zone diameter (IZD) had range of 6-20mm for all bacterial isolates. The pH values of 20 bioactive LHPs range from 3.75- 6.76. In conclusion the study revealed consistent presence and varied occurrences of different phytochemicals and antibiotic properties in various herbal preparations which may be taken to indicate that the products are effective. It is also essential to investigate all LHPs to be used as alternative medication in humans, to ensure that the concentrations used will definitely cause inhibition of the specific bacterial strains and meet its therapeutic claims. Key words: Liquid Herbal Preparations; Phytochemical; Antibacterial Activity

scholarly journals Phytochemical analyses and antibacterial activities of Erodium, Euphorbia, Logoecia and Tamarix species

2019 ◽  
Vol 13 (11) ◽  
pp. 1013-1020
Author(s):  
Khaldoun J Al-Hadid ◽  
Nehaya Al-Karablieh ◽  
Ahmad Sharab ◽  
Ihsan Mutlak
Keyword(s):  
Antibacterial Agents ◽  
Antibacterial Activities ◽  
Microtiter Plate ◽  
Phytochemical Analysis ◽  
Bacterial Strains ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Phytochemical Components ◽  
Promising Source ◽  
Group D

Introduction: Resistance against commonly used antibacterial agents has become a globally recognized threat to human health. Therefore, the development of new and effective antibacterial agents is necessary to treat infections caused by resistant bacterial strains; plants are a promising source of new agents to be tested. Methodology: The minimum inhibitory concentrations (MIC) of ethanolic extracts of Erodium gruinum, Euphorbia hierosolymitana, Logoecia cuminoides, and Tamarix tetragyna against 10 Gram-negative and 5 Gram-positive bacteria were determined using agar well diffusion and microtiter plate dilution methods, respectively. The phytochemical composition of the crude extracts of the plants was determined using HPLC. Results: Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae, Proteus mirabilis, and Acinetobacter baumannii were sensitive to E. gruinum and E. hierosolymitana extracts. P. aeruginosa ATCC 27853 and M. catarrhalis were sensitive to L. cuminoides extract. P. aeruginosa ATCC 27853, P. mirabilis, and K. pneumoniae were sensitive to T. tetragyna extracts. For Gram-positive bacteria, Staphylococcus aureus ATCC 33591 and ATCC 43300 were sensitive to E. gruinum and E. hierosolymitana extracts. S. aureus ATCC 43300 and ATCC 33591 and Group D Streptococcus were sensitive to T. tetragyna extract. All Gram-positive bacteria were completely resistant to the extract of L. cuminoides. The major phytochemical components of the plant extracts belonged to flavonoids, tannins, terpenes, quinones, phytosterols, phytoestrogens, carbohydrates, fatty acids, and coumarin. Conclusion: The study showed the potential of the development of antibacterial agents from these plants. Phytochemical analysis revealed compounds that are candidates for new antibacterial drugs.

scholarly journals PHYTOCHEMICAL ANALYSIS AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF TOKAR SHA AGAINST ENTERIC BACTERIA

2021 ◽  
Vol 5 (1) ◽  
pp. 436-444
Author(s):  
Sabiu Shitu ◽  
M. Attahiru ◽  
F. A. Iliya
Keyword(s):  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Enteric Bacteria ◽  
Antibacterial Activities ◽  
Salmonella Typhi ◽  
Diffusion Method ◽  
Phytochemical Analysis ◽  
North West ◽  
E Coli ◽  
Enteric Infections

The antibacterial activity of Tokar sha; a local traditional medication widely used by many people in North-west zone of Nigeria especially Sokoto, Kebbi and Zamfara against enteric infections were examined against some clinical isolates of pathogenic bacteria (Staphylococcus aureus, Escherichia coli, Bacillus cereus and Salmonella typhi) using agar well diffusion method. The pattern of inhibition varied with the tokar sha concentrations and the organisms tested. The tokar sha was more effective on E. coli with a maximum zone of growth inhibition of 25mm at 35mg/ml followed by B. cereus (20mm). However, S. aureus and S. typhi were resistant to tokar sha at all concentrations tested. The minimum inhibitory concentrations (MIC) were found to be 35mg/ml for both E. coli and B. cereus. The antibacterial activities exhibited by tokar sha in this study could be attributed to the presence of its constituents which signifies the potential of the tokar sha as a therapeutic agent. These findings may justify the ethnomedicinal use of tokar sha as an antibacterial agent against enterobacteria

Antioxidant, antibacterial and cytotoxic activity of Caulerpa racemosa (Forsskål) J. Agardh and Ulva (Enteromorpha) intestinalis L.

2020 ◽  
Vol 55 (4) ◽  
pp. 237-244
Author(s):  
S Aftab Uddin ◽  
S Akter ◽  
S Hossen ◽  
MA Rahman
Keyword(s):  
Ascorbic Acid ◽  
Cytotoxic Activity ◽  
Radical Scavenging ◽  
Inhibition Zone ◽  
Antibacterial Activities ◽  
Diffusion Method ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Enteromorpha Intestinalis ◽  
Caulerpa Racemosa

Seaweeds are fresh sources of phytochemical compounds with immense medicinal potential, which have attracted the attention of agriculture, aquaculture and the pharmaceutical industry. The aim of this study was to test the antioxidant, antibacterial and cytotoxic activity and screening the phytochemical properties of methanol crude extract from two green seaweeds Caulerpa racemosa (Forsskål) J.Agardh and Ulva (Enteromorpha) intestinalis L. The antioxidant and cytotoxic activity of these seaweeds were assessed by 2,2diphenyl, 1-picryl hydrazyl (DPPH) free radical scavenging technique and brine shrimp lethality bioassay method, respectively. The antibacterial activities against Vibrio fluvialis was determined using the standard disc diffusion method. The U. intestinalis showed higher total phenolic content with the value of 149.87 ± 18.17 mg of GAE/g than 73.95 ± 16.09 mg of GAE/g of C. racemosa. However, the recorded inhibition concentration (IC50) to corresponding standards ascorbic acid of C. racemosa and U. intestinalis were 119.62 and 34.274 μg/mL, respectively. The values were statistically significant (p <0.05) compared to the reference antioxidative agent ascorbic acid. In antibacterial assay, C. racemosa extract showed higher inhibition zone (22.65 ± 0.58 mm) than U. intestinalis (17± 0.28 mm). Moreover, U. intestinalis exhibited a lower LC50 value than C. racemosa in cytotoxic activity. Phytochemical analysis revealed that these two seaweeds have alkaloids, flavonoids, glycosides, phenols, saponins, steroids and tannins. Bangladesh J. Sci. Ind. Res.55(4), 237-244, 2020

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