Effect of Cooking Temperature and Time Period on Phytochemical Content and in vitro Antioxidant and Anti-Inflammatory Activity of the Leaf Extracts of Typhonium trilobatum (A Less Focussed Edible Herbal Plant)

doi:10.21275/art20164457

Effect of Cooking Temperature and Time Period on Phytochemical Content and in vitro Antioxidant and Anti-Inflammatory Activity of the Leaf Extracts of Typhonium trilobatum (A Less Focussed Edible Herbal Plant)

International Journal of Science and Research (IJSR) ◽

10.21275/art20164457 ◽

2017 ◽

Vol 6 (1) ◽

pp. 1540-1546

Keyword(s):

Inflammatory Activity ◽

Leaf Extracts ◽

Phytochemical Content ◽

Time Period ◽

Cooking Temperature ◽

Anti Inflammatory ◽

Herbal Plant

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Processed Tart Cherry Products-Comparative Phytochemical Content, in vitro Antioxidant Capacity and in vitro Anti-inflammatory Activity

Journal of Food Science ◽

10.1111/j.1750-3841.2012.02681.x ◽

2012 ◽

Vol 77 (5) ◽

pp. H105-H112 ◽

Cited By ~ 32

Author(s):

Boxin Ou ◽

Kristen N. Bosak ◽

Paula R. Brickner ◽

Dominic G. Iezzoni ◽

E. Mitchell Seymour

Keyword(s):

Antioxidant Capacity ◽

Inflammatory Activity ◽

Tart Cherry ◽

Phytochemical Content ◽

Anti Inflammatory

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Oreganum Vulgare: In-vitro assessment of cytotoxicity, Molecular docking studies, Antioxidant, and evaluation of anti-inflammatory activity in LPS stimulated RAW 264.7 cells

Medicinal Chemistry ◽

10.2174/1573406416666200904110828 ◽

2020 ◽

Vol 16 ◽

Author(s):

Reyaz Hassan Mir ◽

Gifty Sawhney ◽

Rohini Verma ◽

Bilal Ahmad ◽

Parveen Kumar ◽

...

Keyword(s):

Natural Products ◽

Traditional Medicine ◽

Dynamic Network ◽

Docking Studies ◽

Inflammatory Activity ◽

Raw 264.7 Cells ◽

Leaf Extracts ◽

Anti Inflammatory ◽

Isolated Compound

Background: Inflammation involves a dynamic network that is highly regulated by signals that initiate the inflammation process as well as signals that downregulate it. However, an imbalance between the two leads to tissue damage. Throughout the world, inflammatory disease becomes common in the aging society. The drugs which are used clinically suffer serious side effects. Natural products or compounds derived from natural products show diversity in structure and play an important role in drug discovery and development. Objective: Oreganum Vulgare is used in traditional medicine for various ailments including respiratory and rheumatic disorders, severe cold, suppression of tumors. The current study aims to evaluate the anti-inflammatory potential by evaluating various in-vitro parameters. Results: The extracts (OVEE, OVEAF) as well as the isolated compound(OVRA)of Oreganum Vulgare inhibit the proinflammatory cytokines (IL-6 and TNF-α) and NO without affecting cell viability. Conclusion: Our study established that the leaf extracts of Oreganum Vulgare exhibits anti-inflammatory activity and thus confirm its importance in traditional medicine.

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In Vitro Anti-Inflammatory Properties of Selected Green Leafy Vegetables

Biomedicines ◽

10.3390/biomedicines6040107 ◽

2018 ◽

Vol 6 (4) ◽

pp. 107 ◽

Cited By ~ 12

Author(s):

K. Gunathilake ◽

K. Ranaweera ◽

H. Rupasinghe

Keyword(s):

Leaf Extract ◽

Protein Denaturation ◽

Centella Asiatica ◽

Leafy Vegetables ◽

Inflammatory Activity ◽

Leaf Extracts ◽

Percent Inhibition ◽

Lipoxygenase Inhibition ◽

Anti Inflammatory

The study investigated the anti-inflammatory activity of the hydro methanolic extract of six leafy vegetables, namely Cassia auriculata, Passiflora edulis, Sesbania grandiflora, Olax zeylanica, Gymnema lactiferum, and Centella asiatica. The anti-inflammatory activity of methanolic extracts of leafy vegetables was evaluated using four in vitro-based assays: hemolysis inhibition, proteinase inhibition, protein denaturation inhibition, and lipoxygenase inhibition. Results showed that the percent inhibition of hemolysis from these leaf extracts (25–100 µg/mL dry weight basis (DW)) was within the range from 5.4% to 14.9%, and the leaves of P. edulis and O. zeylanica showed a significantly higher (p < 0.05) inhibition levels. Percent inhibition of protein denaturation of these leafy types was within the range of 36.0–61.0%, and the leaf extract of C. auriculata has exhibited a significantly higher (p < 0.05) inhibition level. Proteinase inhibitory activity of these leaf extracts was within the range of 20.2–25.9%. The lipoxygenase inhibition was within the range of 3.7–36.0%, and the leaf extract of G. lactiferum showed an improved ability to inhibit lipoxygenase activity. In conclusion, results revealed that all the studied leaves possess anti-inflammatory properties at different levels, and this could be due to the differences in the composition and concentration of bioactive compounds.

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ANTI-INFLAMMATORY ACTIVITY OF MANILKARA ZAPOTA LEAF EXTRACT

International Journal of Current Pharmaceutical Research ◽

10.22159/ijcpr.2017v9i4.20977 ◽

2017 ◽

Vol 9 (4) ◽

pp. 130 ◽

Cited By ~ 1

Author(s):

Kamalakararao Konuku ◽

Krishna Chaithanya Karri ◽

Velliyur Kanniappan Gopalakrishnan ◽

Zenebe Hagos ◽

Haftom Kebede ◽

...

Keyword(s):

Ethyl Acetate ◽

Leaf Extract ◽

Inflammatory Activity ◽

In Vivo Studies ◽

Paw Edema ◽

Leaf Extracts ◽

Manilkara Zapota ◽

Anti Inflammatory

Objective: Manilkara zapota is a medicinal plant which is native to Mexico and Central America, and widely distributed in India. Various parts of this plant are traditionally used for treatment of several diseases, including inflammation-associated ailments. The main aim of the present study is to evaluate the anti-inflammatory potential of ethyl acetate and methanolic extracts of M. zapota leaf.Methods: In vitro secretary phospholipase A2 (PLA2) and 5-Lipoxygenase (5-LOX) assays and In vivo studies using carrageenan induced rat paw edema model were performed to assess the anti-inflammatory activity of M. zapota leaf extracts.Results: In vitro studies suggest that M. zapota leaf extracts exhibited significant SPLA2 and 5-LOX inhibitory activities. In in vivo studies M. zapota leaf extracts showed dose dependent inhibition of carrageenan induced paw edema in rats. The anti-inflammatory activity of ethyl acetate leaf extract was superior to methanolic extract.Conclusion: This study concluded that ethyl acetate leaf extract of M. zapotaexhibited significant anti-inflammatory activity and warranted further investigation to isolate and identify the components.

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