Novel Combinatory Approaches to Repair Visual System after Optic Nerve Damage

2014 ◽  
Author(s):  
Kevin K. Park
Keyword(s):  
Optic Nerve ◽  
Visual System ◽  
Nerve Damage ◽  
Optic Nerve Damage

Visual processing of the zebrafish optic tectum before and after optic nerve damage

2004 ◽  
Vol 21 (2) ◽  
pp. 97-106 ◽  
Author(s):  
ANGELA L. McDOWELL ◽  
LEE J. DIXON ◽  
JENNIFER D. HOUCHINS ◽  
JOSEPH BILOTTA
Keyword(s):  
Optic Nerve ◽  
Visual System ◽  
Spectral Sensitivity ◽  
Visual Processing ◽  
Nerve Damage ◽  
Neural Regeneration ◽  
Nerve Crush ◽  
Sensitivity Functions ◽  
Optic Nerve Damage ◽  
Zebrafish Optic Tectum

Although the zebrafish has become an important model in visual neuroscience, little has been done to examine the processing of its higher visual centers. The purpose of this work was twofold. The first purpose was to examine the physiology of the zebrafish retinotectal system and its relationship to retinal physiology. Spectral sensitivity functions were derived from visually evoked tectal responses and these functions were compared to the functions of electroretinogram (ERG) responses obtained using the same stimulus conditions. The second purpose was to examine the recovery of visual functioning of the tectum following optic nerve damage. The optic nerves of adult zebrafish were damaged (crushed), and tectal visual processing was assessed following damage. The results showed that the spectral sensitivity functions based on the On-responses of the tectum and ERG were qualitatively similar. The functions based on each response type received similar cone contributions including both nonopponent and opponent contributions. However, the spectral sensitivity functions based on the Off-responses of the tectum and ERG differed. The results also showed that the zebrafish visual system is capable of neural regeneration. By 90 days following an optic nerve crush, the spectral sensitivity function based on the tectal On-response was similar to functions obtained from normal zebrafish. Although the tectal Off-response did recover, the spectral sensitivity based on the Off-response was not the same as the function of normal zebrafish. These results support the notion that different levels of the visual system process information differently and that the zebrafish visual system, like those of other lower vertebrates, is capable of functional regeneration.

Optic Nerve Damage in Alzheimer's Disease

Ophthalmology ◽  
1990 ◽  
Vol 97 (1) ◽  
pp. 9-17 ◽  
Author(s):  
Alfredo A. Sadun ◽  
Carl J. Bassi
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Optic Nerve ◽  
Nerve Damage ◽  
Optic Nerve Damage

scholarly journals Taurine protects against retinal and optic nerve damage induced by endothelin-1 in rats via antioxidant effects

2018 ◽  
Vol 13 (11) ◽  
pp. 2014 ◽  
Author(s):  
Renu Agarwal ◽  
NatashaNajwa Nor Arfuzir ◽  
Igor Iezhitsa ◽  
Puneet Agarwal ◽  
Sabrilhakim Sidek ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Nerve Damage ◽  
Endothelin 1 ◽  
Optic Nerve Damage ◽  
Antioxidant Effects

scholarly journals A Case of Locally Invasive Fungal Sinusitis Resulting in Optic Nerve Damage

2012 ◽  
Vol 23 (2) ◽  
pp. 270-273
Author(s):  
Jung-Hoon Lee ◽  
Chan-Hwi Park ◽  
Kyu-Sup Cho ◽  
Hwan-Jung Roh
Keyword(s):  
Optic Nerve ◽  
Nerve Damage ◽  
Fungal Sinusitis ◽  
Optic Nerve Damage ◽  
Invasive Fungal Sinusitis

Comparisons of Methods To Detect Glaucomatous Optic Nerve Damage

Ophthalmology ◽  
1993 ◽  
Vol 100 (10) ◽  
pp. 1498-1503 ◽  
Author(s):  
Daniel J. O'Connor ◽  
Thierry Zeyen ◽  
Joseph Caprioli
Keyword(s):  
Optic Nerve ◽  
Nerve Damage ◽  
Optic Nerve Damage

Letter to the Editor. Low ICP and normal tension glaucoma: optic nerve damage due to barotraumatic factors, failure of CSF dynamics, or both?

2018 ◽  
Vol 129 (4) ◽  
pp. 1100-1103
Author(s):  
Peter Wostyn ◽  
Veva De Groot ◽  
Debby Van Dam ◽  
Kurt Audenaert ◽  
Peter Paul De Deyn ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Normal Tension Glaucoma ◽  
Nerve Damage ◽  
Csf Dynamics ◽  
Optic Nerve Damage ◽  
Letter To The Editor
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