Role of Ca++ Influx via Epidermal TRP Ion Channels

2014 ◽  
Author(s):  
Wolfgang Liedtke
Keyword(s):  
Ion Channels ◽  
Trp Ion Channels

Role of TRP Ion Channels in Pruritus

2021 ◽  
pp. 136379
Author(s):  
Parth Shirolkar ◽  
Santosh K. Mishra
Keyword(s):  
Ion Channels ◽  
Trp Ion Channels

The role of TRP ion channels in migraine and headache

2021 ◽  
pp. 136380
Author(s):  
Luigi Francesco Iannone ◽  
Francesco De Logu ◽  
Pierangelo Geppetti ◽  
Francesco De Cesaris
Keyword(s):  
Ion Channels ◽  
Trp Ion Channels

Role of TRP ion channels in cancer and tumorigenesis

2016 ◽  
Vol 38 (3) ◽  
pp. 357-369 ◽  
Author(s):  
George Shapovalov ◽  
Abigael Ritaine ◽  
Roman Skryma ◽  
Natalia Prevarskaya
Keyword(s):  
Ion Channels ◽  
Trp Ion Channels

The Role of TRP Channels in Allergic Inflammation and its Clinical Relevance

2020 ◽  
Vol 27 (9) ◽  
pp. 1446-1468 ◽  
Author(s):  
Joo Hyun Nam ◽  
Woo Kyung Kim
Keyword(s):  
T Cells ◽  
Ion Channels ◽  
Mast Cells ◽  
Immune Cells ◽  
Trp Channels ◽  
Allergic Inflammation ◽  
Current Status ◽  
Calcium Signal ◽  
Trp Ion Channels

Allergy refers to an abnormal adaptive immune response to non-infectious environmental substances (allergen) that can induce various diseases such as asthma, atopic dermatitis, and allergic rhinitis. In this allergic inflammation, various immune cells, such as B cells, T cells, and mast cells, are involved and undergo complex interactions that cause a variety of pathophysiological conditions. In immune cells, calcium ions play a crucial role in controlling intracellular Ca2+ signaling pathways. Cations, such as Na+, indirectly modulate the calcium signal generation by regulating cell membrane potential. This intracellular Ca2+ signaling is mediated by various cation channels; among them, the Transient Receptor Potential (TRP) family is present in almost all immune cell types, and each channel has a unique function in regulating Ca2+ signals. In this review, we focus on the role of TRP ion channels in allergic inflammatory responses in T cells and mast cells. In addition, the TRP ion channels, which are attracting attention in clinical practice in relation to allergic diseases, and the current status of the development of therapeutic agents that target TRP channels are discussed.

scholarly journals Modeling TMJD pain in the laboratory mouse: role of TRP ion channels

2014 ◽  
Vol 10 (Suppl 1) ◽  
pp. O8 ◽  
Author(s):  
Yong Chen ◽  
Fan Wang ◽  
Wolfgang Liedtke
Keyword(s):  
Ion Channels ◽  
Laboratory Mouse ◽  
Trp Ion Channels

Role of TRP ion channels in cerebral circulation and neurovascular communication

2021 ◽  
Vol 765 ◽  
pp. 136258
Author(s):  
Maniselvan Kuppusamy ◽  
Matteo Ottolini ◽  
Swapnil K. Sonkusare
Keyword(s):  
Ion Channels ◽  
Cerebral Circulation ◽  
Trp Ion Channels
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