Refining an Automated Transcranial Doppler System for the Detection of Vasospasm after Traumatic Brain Injury

2013 ◽  
Author(s):  
Pierre D. Mourad
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler ◽  
Doppler System

scholarly journals Experimental model of intracranial hypertension with continuous multiparametric monitoring in swine

2013 ◽  
Vol 71 (10) ◽  
pp. 802-806 ◽  
Author(s):  
Almir Ferreira de Andrade ◽  
Matheus Schmidt Soares ◽  
Gustavo Cartaxo Patriota ◽  
Alessandro Rodrigo Belon ◽  
Wellingson Silva Paiva ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Animal Model ◽  
Brain Injury ◽  
Intracranial Pressure ◽  
Intracranial Hypertension ◽  
Severe Traumatic Brain Injury ◽  
Transcranial Doppler ◽  
Porcine Model ◽  
Cerebral Oximetry ◽  
Suitable Animal Model

Objective Intracranial hypertension (IH) develops in approximately 50% of all patients with severe traumatic brain injury (TBI). Therefore, it is very important to identify a suitable animal model to study and understand the pathophysiology of refractory IH to develop effective treatments. Methods We describe a new experimental porcine model designed to simulate expansive brain hematoma causing IH. Under anesthesia, IH was simulated with a balloon insufflation. The IH variables were measured with intracranial pressure (ICP) parenchymal monitoring, epidural, cerebral oximetry, and transcranial Doppler (TCD). Results None of the animals died during the experiment. The ICP epidural showed a slower rise compared with parenchymal ICP. We found a correlation between ICP and cerebral oximetry. Conclusion The model described here seems useful to understand some of the pathophysiological characteristics of acute IH.

scholarly journals Transcranial Doppler Systolic Flow Index and ICP-Derived Cerebrovascular Reactivity Indices in Traumatic Brain Injury

2018 ◽  
Vol 35 (2) ◽  
pp. 314-322 ◽  
Author(s):  
Frederick A. Zeiler ◽  
Danilo Cardim ◽  
Joseph Donnelly ◽  
David K. Menon ◽  
Marek Czosnyka ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler ◽  
Cerebrovascular Reactivity ◽  
Flow Index ◽  
Reactivity Indices

Transcranial Doppler after traumatic brain injury

2014 ◽  
Vol 20 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Pierre Bouzat ◽  
Mauro Oddo ◽  
Jean-François Payen
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler

PULSATILITY INDEX MEASURED BY TRANSCRANIAL DOPPLER IS USEFUL AS A PROGNOSTIC INDEX FOR NEUROLOGICAL OUTCOMES IN TRAUMATIC BRAIN INJURY.

2006 ◽  
Vol 34 ◽  
pp. A141
Author(s):  
Juan A Calderon ◽  
Luis Espinosa-Sierra ◽  
Felipe J Perez-Rada ◽  
Fernando CastillejaLeal ◽  
Jose L Chavez-Trevino ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler ◽  
Pulsatility Index ◽  
Prognostic Index ◽  
Neurological Outcomes

Critical Thresholds for Transcranial Doppler Indices of Cerebral Autoregulation in Traumatic Brain Injury

2010 ◽  
Vol 14 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Enrico Sorrentino ◽  
Karol P. Budohoski ◽  
Magdalena Kasprowicz ◽  
Peter Smielewski ◽  
Basil Matta ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler ◽  
Cerebral Autoregulation ◽  
Critical Thresholds ◽  
Doppler Indices

Serial Transcranial Doppler Measurements in Traumatic Brain Injury with Special Focus on the Early Posttraumatic Period

2002 ◽  
Vol 144 (11) ◽  
pp. 1141-1149 ◽  
Author(s):  
H. van Santbrink ◽  
J. W. Schouten ◽  
E. W. Steyerberg ◽  
C. J. J. Avezaat ◽  
A. I. R. Maas
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Transcranial Doppler ◽  
Special Focus

scholarly journals P.186 Transcranial Doppler Based Continuous Assessment of Cerebrovascular Reactivity in Adult Traumatic Brain Injury: A Scoping Review of Associations with Outcomes

2021 ◽  
Vol 48 (s3) ◽  
pp. S73-S74
Author(s):  
A Gomez ◽  
L Froese ◽  
AS Sainbhi ◽  
C Batson ◽  
FA Zeiler
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Scoping Review ◽  
Time Domain ◽  
Transcranial Doppler ◽  
Continuous Time ◽  
Cerebrovascular Reactivity ◽  
Continuous Assessment ◽  
Physiologic Parameters ◽  
Carbon Dioxide Co2

Background: Disruption in cerebrovascular reactivity following traumatic brain injury (TBI) is a known phenomenon that may hold prognostic value. Transcranial Doppler (TCD) has been employed to evaluate cerebrovascular reactivity following injury utilizing a continuous time-series approach. Methods: A systematically conducted scoping review of the literature on the association of continuous time-domain TCD based indices of cerebrovascular reactivity, with outcomes following moderate and severe TBI was performed. Multiple databases were searched from inception to November 2020 for relevant articles. Results: Thirty-six relevant articles were identified. There was significant evidence supporting an association with continuous time-domain TCD based indices and functional outcomes following TBI. Physiologic parameters such as intracranial pressure, cerebral perfusion pressure, Carbon Dioxide (CO2) reactivity as well as more established indices of cerebrovascular reactivity have all been associated with these TCD based indices. The literature has been concentrated in a few centres and is further limited by the lack of multivariate analysis. Conclusions: There is a substantial body of evidence that cerebrovascular reactivity as measured by time-domain TCD based indices have prognostic utility following TBI. The literature supports some associations between these indices and cerebral physiologic parameters. Further validation in multi-institution studies is required before these indices can be widely adopted clinically.

Sign in / Sign up

Export Citation Format

Share Document