Use of GDNF-Releasing Nanofiber Nerve Guide Conduits for the Repair of Conus Medullaris/Cauda Equina Injury in the Nonhuman Primate

2012 ◽  
Author(s):  
Ahmet Hoke ◽  
Hai-Quan Mao
Keyword(s):  
Nonhuman Primate ◽  
Cauda Equina ◽  
Conus Medullaris

scholarly journals Anaplastic pilocytic astrocytoma of the cerebellum presenting with conus medullaris drop metastasis

2021 ◽  
Vol 8 (1) ◽  
pp. 10
Author(s):  
Jared F. Sweeney ◽  
Vaibhav Chumbalkar ◽  
Michael D. Staudt ◽  
Pouya Entezami ◽  
Jiang Qian ◽  
...  
Keyword(s):  
Pilocytic Astrocytoma ◽  
Cauda Equina ◽  
Conus Medullaris ◽  
Complete Understanding ◽  
First Case ◽  
Spine Imaging ◽  
Drop Metastasis ◽  
Cerebellar Mass ◽  
Definition Of ◽  
Staged Operations

Due to its rarity, a complete understanding of the clinical behavior, pathogenesis, and diagnostic definition of anaplastic pilocytic astrocytoma (APA) is currently lacking. The optimal clinical management and use of adjuvant therapies has yet to be defined. We present a 64 year-old-female with progressive headaches, dysarthria, and ataxia, who was found to have right cerebellar mass. A gross total resection was achieved through two staged operations. Pathology demonstrated focal areas of necrosis, tumor infiltration, and increased mitotic activity most consistent with APA. Adjuvant chemotherapy and stereotactic radiosurgery were administered. Approximately two years later, the patient presented with symptoms of cauda equina syndrome, and lumbar spine imaging demonstrated a large intradural mass at the conus medullaris with diffuse leptomeningeal enhancement. A biopsy was performed and was consistent with metastatic APA. APA may rarely progress to metastatic disease, most frequently involving the leptomeninges of the posterior fossa and cervical spine. This report represents the first case of metastases distal to the cervicomedullary junction.

Dermoid tumors of the spinal cord

1970 ◽  
Vol 33 (6) ◽  
pp. 676-681 ◽  
Author(s):  
Ian C. Bailey
Keyword(s):  
Spinal Cord ◽  
Low Back Pain ◽  
Back Pain ◽  
Cauda Equina ◽  
Complete Removal ◽  
Cord Compression ◽  
Conus Medullaris ◽  
Low Back ◽  
Content Type ◽  
Fine Print

✓ This is an analysis of 10 cases of dermoid tumor occurring in the spinal canal (8 lumbar and 2 thoracic). Low-back pain was the commonest presenting symptom, especially if the tumor was adherent to the conus medullaris. Other complaints included urinary dysfunction and motor and sensory disturbances of the legs. Clinical and radiological evidence of spina bifida was found in about half of the cases and suggested the diagnosis of a developmental type of tumor when patients presented with progressive spinal cord compression. At operation, the tumors were often found embedded in the conus medullaris or firmly adherent to the cauda equina, thus precluding complete removal. Evacuation of the cystic contents, however, gave lasting relief of the low-back pain and did not cause any deterioration in neurological function. In a follow-up study, ranging from 1 to 15 years, virtually no improvement in the neurological signs was observed. On the other hand, only one case has deteriorated due to recurrence of tumor growth.

Cauda Equina and Conus Medullaris Lesions

2021 ◽  
pp. 225-235
Author(s):  
Hyun-Yoon Ko ◽  
Sungchul Huh
Keyword(s):  
Cauda Equina ◽  
Conus Medullaris

Electrophysiological evaluation of the afferent spinal roots and nerves in patients with conus medullaris and cauda equina lesions

1980 ◽  
Vol 48 (3) ◽  
pp. 419-433 ◽  
Author(s):  
Cumhur Ertekin ◽  
Rifat Mutlu ◽  
Yakup Sarica ◽  
Levent Uçkardeşler
Keyword(s):  
Cauda Equina ◽  
Conus Medullaris ◽  
Spinal Roots

Clinical features of intradural neurinomas in the cauda equina and around the conus medullaris

1992 ◽  
Vol 35 (05) ◽  
pp. 145-149 ◽  
Author(s):  
J. Hanakita ◽  
H. Suwa ◽  
S. Nagayasu ◽  
S. Nishi ◽  
K. Iihara ◽  
...  
Keyword(s):  
Clinical Features ◽  
Cauda Equina ◽  
Conus Medullaris
Sign in / Sign up

Export Citation Format

Share Document