scholarly journals Overcoming the Practical Barriers to Spinal Cord Cell Transplantation for ALS

2012 ◽  
Author(s):  
Nicholas Boulis
Keyword(s):  
Spinal Cord ◽  
Cell Transplantation ◽  
Spinal Cord Cell

scholarly journals A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis

2010 ◽  
Vol 191 (2) ◽  
pp. 255-257 ◽  
Author(s):  
Miguel Blanquer ◽  
Miguel Angel Pérez-Espejo ◽  
Juan F. Martínez-Lage ◽  
Francisca Iniesta ◽  
Salvador Martinez ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Amyotrophic Lateral Sclerosis ◽  
Surgical Technique ◽  
Cell Transplantation ◽  
Spinal Cord Cell ◽  
Lateral Sclerosis

Stem Cell Transplantation: A Promising Therapy for Spinal Cord Injury

2020 ◽  
Vol 15 (4) ◽  
pp. 321-331 ◽  
Author(s):  
Zhe Gong ◽  
Kaishun Xia ◽  
Ankai Xu ◽  
Chao Yu ◽  
Chenggui Wang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Stem Cells ◽  
Spinal Cord Injury ◽  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Therapeutic Potential ◽  
Embryonic Stem ◽  
Current Status ◽  
Cord Injury

Spinal Cord Injury (SCI) causes irreversible functional loss of the affected population. The incidence of SCI keeps increasing, resulting in huge burden on the society. The pathogenesis of SCI involves neuron death and exotic reaction, which could impede neuron regeneration. In clinic, the limited regenerative capacity of endogenous cells after SCI is a major problem. Recent studies have demonstrated that a variety of stem cells such as induced Pluripotent Stem Cells (iPSCs), Embryonic Stem Cells (ESCs), Mesenchymal Stem Cells (MSCs) and Neural Progenitor Cells (NPCs) /Neural Stem Cells (NSCs) have therapeutic potential for SCI. However, the efficacy and safety of these stem cellbased therapy for SCI remain controversial. In this review, we introduce the pathogenesis of SCI, summarize the current status of the application of these stem cells in SCI repair, and discuss possible mechanisms responsible for functional recovery of SCI after stem cell transplantation. Finally, we highlight several areas for further exploitation of stem cells as a promising regenerative therapy of SCI.

Safety of Autologous Bone Marrow Stromal Cell Transplantation in Dogs with Acute Spinal Cord Injury

2012 ◽  
Vol 41 (4) ◽  
pp. 437-442 ◽  
Author(s):  
Hidetaka Nishida ◽  
Masanari Nakayama ◽  
Hiroshi Tanaka ◽  
Masahiko Kitamura ◽  
Shingo Hatoya ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Bone Marrow ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Autologous Bone Marrow ◽  
Marrow Stromal Cell ◽  
Cord Injury ◽  
Autologous Bone

The Use of Cell Transplantation in Spinal Cord Injuries

2016 ◽  
Vol 24 (4) ◽  
pp. 266-275 ◽  
Author(s):  
Gregory D. Schroeder ◽  
Christopher K. Kepler ◽  
Alexander R. Vaccaro
Keyword(s):  
Spinal Cord ◽  
Cell Transplantation ◽  
Spinal Cord Injuries
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