Engineered PlyCB as a Novel Implant Coating for Osseointegration

2012 ◽  
Author(s):  
Daniel Nelson
Keyword(s):  
Implant Coating

Local drug delivery by personalized, intraoperative custom-made implant coating

2013 ◽  
Vol 101B (6) ◽  
pp. 950-963
Author(s):  
B. Trajkovski ◽  
A. Petersen ◽  
C. Perka ◽  
N. Scharnagl ◽  
C. Wischke ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Local Drug Delivery ◽  
Custom Made ◽  
Implant Coating

scholarly journals Antibacterial bioglass in dental implants: a canine clinical study

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Silvia Gavinho ◽  
Manuel Graca ◽  
Pedro Prezas ◽  
João Borges ◽  
Jorge Silva ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Study ◽  
Tissue Regeneration ◽  
Histological Analysis ◽  
Bone Structure ◽  
Bacterial Activity ◽  
Ct Scans ◽  
Fusion Method ◽  
Tissue Integration ◽  
Implant Coating

Abstract Background Peri-implantitis is considered the most challenging biological complication in implantology, as untreated disease can progress and result in implant loss. Therefore, disease prevention is crucial in daily clinical practice. It has been reported that the use of bioactive glass, as an implant coating, can stimulate tissue integration and accelerate tissue regeneration. Besides these properties, it is possible to promote bacterial activity by inserting silver into the bioglass Methods Bioglass with composition 45S5 was synthesised by the fusion method, replacing the amount of Na2CO3 by AgNO3 (BG 2% wt). The implants were resealed by the CoBlast® technique. Clinical cases with pathology of the mandible/maxilla were selected and implants dimensioned for the canine bone structure were applied. Results Three months after implantation, imaging exams, namely CT scans, showed no signs of early rejection by septic or cytotoxic loss. No decrease or loss of peri-implant bone was observed. In all cases the implants remained without signs of instability, and with sufficient support for the application of the exo-prosthesis or dental crown. The results of histological analysis showed no signs of infection or osteolysis. The zone of peri-implant fibrosis was not observable in the samples, showing a good evolution in implant osteointegration. Conclusions The results show promising evidences for the use of this biomaterial as a coating, since aseptic rejection, later on, and that related to the shape and biomaterials used in the implant's design, usually begins during the first 3 months.

scholarly journals Infections @ Trauma/Orthopedic Implants: Recent Advances on Materials, Methods, and Microbes—A Mini-Review

Materials ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 5834
Author(s):  
Britt Wildemann ◽  
Klaus D. Jandt
Keyword(s):  
Surface Modification ◽  
Animal Studies ◽  
Orthopedic Implants ◽  
Implant Design ◽  
Bacterial Survival ◽  
Implant Surface ◽  
Antimicrobial Surfaces ◽  
Pubmed Search ◽  
Implant Coating ◽  
Antibiotic Release

Implants and materials are indispensable in trauma and orthopedic surgery. The continuous improvements of implant design have resulted in an optimized mechanical function that supports tissue healing and restoration of function. One of the still unsolved problems with using implants and materials is infection. Trauma and material implantation change the local inflammatory situation and enable bacterial survival and material colonization. The main pathogen in orthopedic infections is Staphylococcus aureus. The research efforts to optimize antimicrobial surfaces and to develop new anti-infective strategies are enormous. This mini-review focuses on the publications from 2021 with the keywords S. aureus AND (surface modification OR drug delivery) AND (orthopedics OR trauma) AND (implants OR nails OR devices). The PubMed search yielded 16 original publications and two reviews. The original papers reported the development and testing of anti-infective surfaces and materials: five studies described an implant surface modification, three developed an implant coating for local antibiotic release, the combination of both is reported in three papers, while five publications are on antibacterial materials but not metallic implants. One review is a systematic review on the prevention of stainless-steel implant-associated infections, the other addressed the possibilities of mixed oxide nanotubes. The complexity of the approaches differs and six of them showed efficacy in animal studies.

BIOACTIVE GLASS PARTICLES FIELD-ASSISTED SEALING TO TITANIUM IMPLANT GLASS-BASED COATINGS

2009 ◽  
Vol 16 (01) ◽  
pp. 1-3 ◽  
Author(s):  
PIOTR MROZEK
Keyword(s):  
Bioactive Glass ◽  
Enamel Coating ◽  
Titanium Implant ◽  
Glass Particle ◽  
Anodic Bonding ◽  
Polished Surface ◽  
Glass Enamel ◽  
Glass Enamel Coating ◽  
Implant Coating ◽  
First Time

This paper reports for the first time the use of field-assisted sealing for bioactive implant coating applications. Field-assisted sealing (anodic bonding) of bioactive glass particles to bioinert glass enamel coating of titanium implant was investigated. Biocompatible titanium oxide interlayer was fabricated by deep thermal oxidation of 80 nm thick Ti thin film previously vacuum evaporated onto polished bioactive glass surface. Bioactive glass particle was anodically bonded via the interlayer to polished surface of bioinert glass enamel coating vacuum deposited onto Ti plate at 860°C. A total of 20 min preheating time with constant temperature increase rate, 5 min bonding time, and 100 V DC voltage were applied during field-assisted bond formation at 530°C in air.

Enhanced Osteoblast Adhesion on a Novel Hydroxyapatite Coating

2003 ◽  
Vol 774 ◽  
Author(s):  
Michiko Sato ◽  
Elliott B. Slamovich ◽  
Thomas J. Webster
Keyword(s):  
Glycolic Acid ◽  
Spray Deposition ◽  
Sol Gel ◽  
Titanium Implant ◽  
Coating Material ◽  
Ha Coating ◽  
Implant Coating ◽  
Osteoblast Adhesion ◽  
Plasma Sprayed ◽  
Gel Processing

AbstractPlasma spray deposition of hydroxyapatite (HA) onto a titanium implant involves high temperatures that may alter HA crystallinity and induce cracks in the coating. For this reason, the objective of this study was to design a novel HA coating material and method. Titanium was coated with HA, titania, and Poly (dl-lactic-glycolic acid) (PLGA) using sol-gel processing. The biocompatibility of the HA coating in the present study was compared to that of a plasmasprayed HA coating. Results of this study showed that osteoblast adhesion was promoted more in the HA coating proposed in this study than on the plasma-sprayed HA coating. In addition, hydrothermal treatment of the coating appeared to improve the biocompatibility of the HA coating. Since osteoblast adhesion is a necessary requirement for increased bonding of an implant to juxtaposed bone, these results support that hydrothermally sol-gel processed HA may be an optimal implant coating material and method.

Magnesium-containing layered double hydroxides as orthopaedic implant coating materials-Anin vitroandin vivostudy

2015 ◽  
Vol 104 (3) ◽  
pp. 525-531 ◽  
Author(s):  
Andreas Weizbauer ◽  
Marc Kieke ◽  
Muhammad Imran Rahim ◽  
Gian Luigi Angrisani ◽  
Elmar Willbold ◽  
...  
Keyword(s):  
Layered Double Hydroxides ◽  
Orthopaedic Implant ◽  
Coating Materials ◽  
Implant Coating ◽  
Double Hydroxides

A novel graded bioactive high adhesion implant coating

2009 ◽  
Vol 255 (17) ◽  
pp. 7723-7728 ◽  
Author(s):  
Ulrika Brohede ◽  
Shuxi Zhao ◽  
Fredrik Lindberg ◽  
Albert Mihranyan ◽  
Johan Forsgren ◽  
...  
Keyword(s):  
High Adhesion ◽  
Implant Coating
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