Improving Synchronization and Functional Connectivity in Autism Spectrum Disorders through Plasticity-Induced Rehabilitation Training

2011 ◽  
Author(s):  
Jaime A. Pineda ◽  
Ralph-Axel Mueller
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Autism Spectrum ◽  
Rehabilitation Training ◽  
Spectrum Disorders

scholarly journals Emerging functional connectivity differences in newborn infants vulnerable to autism spectrum disorders

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Judit Ciarrusta ◽  
Ralica Dimitrova ◽  
Dafnis Batalle ◽  
Jonathan O’Muircheartaigh ◽  
Lucilio Cordero-Grande ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Newborn Infants ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals Local and long-range functional connectivity is reduced in concert in autism spectrum disorders

2013 ◽  
Vol 110 (8) ◽  
pp. 3107-3112 ◽  
Author(s):  
S. Khan ◽  
A. Gramfort ◽  
N. R. Shetty ◽  
M. G. Kitzbichler ◽  
S. Ganesan ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Long Range ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals Using a self-organizing map algorithm to detect age-related changes in functional connectivity during rest in autism spectrum disorders

2011 ◽  
Vol 1380 ◽  
pp. 187-197 ◽  
Author(s):  
Jillian Lee Wiggins ◽  
Scott J. Peltier ◽  
Samantha Ashinoff ◽  
Shih-Jen Weng ◽  
Melisa Carrasco ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Autism Spectrum ◽  
Self Organizing Map ◽  
Map Algorithm ◽  
Age Related ◽  
Spectrum Disorders ◽  
Age Related Changes ◽  
Self Organizing

scholarly journals Amygdala Habituation and Prefrontal Functional Connectivity in Youth With Autism Spectrum Disorders

2013 ◽  
Vol 52 (1) ◽  
pp. 84-93 ◽  
Author(s):  
Johnna R. Swartz ◽  
Jillian Lee Wiggins ◽  
Melisa Carrasco ◽  
Catherine Lord ◽  
Christopher S. Monk
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals Mixed Effects Models for Resampled Network Statistics Improves Statistical Power to Find Differences in Multi-Subject Functional Connectivity

2015 ◽  
Author(s):  
Manjari Narayan ◽  
Genevera I. Allen
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Network Structure ◽  
Symptom Severity ◽  
Statistical Power ◽  
Autism Spectrum ◽  
Covariate Effects ◽  
Activity Measurements ◽  
Wide Range ◽  
Spectrum Disorders

AbstractMany complex brain disorders, such as autism spectrum disorders, exhibit a wide range of symptoms and disability. To understand how brain communication is impaired in such conditions, functional connectivity studies seek to understand individual differences in brain network structure in terms of covariates that measure symptom severity. In practice, however, functional connectivity is not observed but estimated from complex and noisy neural activity measurements. Imperfect subject network estimates can compromise subsequent efforts to detect covariate effects on network structure. We address this problem in the case of Gaussian graphical models of functional connectivity, by proposing novel two-level models that treat both subject level networks and population level covariate effects as unknown parameters. To account for imperfectly estimated subject level networks when fitting these models, we propose two related approaches — R2 based on resampling and random effects test statistics, and R3 that additionally employs random adaptive penalization. Simulation studies using realistic graph structures reveal that R2 and R3 have superior statistical power to detect covariate effects compared to existing approaches, particularly when the number of within subject observations is comparable to the size of subject networks. Using our novel models and methods to study parts of the ABIDE dataset, we find evidence of hypoconnectivity associated with symptom severity in autism spectrum disorders, in frontoparietal and limbic systems as well as in anterior and posterior cingulate cortices.

Abnormal Structural and Functional Connectivity of the Corpus Callosum in Autism Spectrum Disorders: a Review

2019 ◽  
Vol 7 (1) ◽  
pp. 46-62 ◽  
Author(s):  
Marco Valenti ◽  
Maria Chiara Pino ◽  
Monica Mazza ◽  
Gianvito Panzarino ◽  
Claudio Di Paolantonio ◽  
...  
Keyword(s):  
Autism Spectrum Disorders ◽  
Functional Connectivity ◽  
Corpus Callosum ◽  
Autism Spectrum ◽  
Spectrum Disorders
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