Role of Angiogenesis in the Etiology and Prevention of Ovarian Cancer. Project 1: Effect of Angiogenesis Inhibitors in Preventing Ovarian Cancer Growth

2002 ◽  
Author(s):  
Sundaram Ramakrishnan
Keyword(s):  
Ovarian Cancer ◽  
Angiogenesis Inhibitors ◽  
Cancer Growth ◽  
Cancer Project

p53 Directs Role of Smads in Ovarian Cancer Growth and Metastasis

2011 ◽  
pp. P2-213-P2-213
Author(s):  
Roshan A Ahmed ◽  
Joanna E Burdette
Keyword(s):  
Ovarian Cancer ◽  
Cancer Growth

p53 Directs the Role of Smads in Ovarian Cancer Growth and Metastasis.

2010 ◽  
Vol 83 (Suppl_1) ◽  
pp. 689-689
Author(s):  
Roshan Ahmed ◽  
Joanna E. Burdette ◽  
Kari Inoue
Keyword(s):  
Ovarian Cancer ◽  
Cancer Growth

Abstract 4467: Role of 12-lipoxygenase in regulation of ovarian cancer growth

2011 ◽  
Author(s):  
Austin M. Guo ◽  
Zaid Al-Wahab ◽  
Xiuli Liu ◽  
Krishna Rao Maddippadi ◽  
Rouba Ali ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cancer Growth ◽  
12 Lipoxygenase

Abstract 1882: Role of cystathionine beta-synthase in ovarian cancer growth, metastasis and drug sensitivity.

2013 ◽  
Author(s):  
Sounik Saha ◽  
Sanjib Bhattacharyya ◽  
Karuna Giri ◽  
Ian R. Lanza ◽  
K. Sreekumar Nair ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Drug Sensitivity ◽  
Cancer Growth ◽  
Cystathionine Beta Synthase

Extracellular matrix: the gatekeeper of tumor angiogenesis

2019 ◽  
Vol 47 (5) ◽  
pp. 1543-1555 ◽  
Author(s):  
Maurizio Mongiat ◽  
Simone Buraschi ◽  
Eva Andreuzzi ◽  
Thomas Neill ◽  
Renato V. Iozzo
Keyword(s):  
Extracellular Matrix ◽  
Tumor Angiogenesis ◽  
Signaling Cascades ◽  
Cancer Growth ◽  
Cell Behavior ◽  
Metastatic Progression ◽  
Surface Receptors ◽  
The Matrix ◽  
Multiple Signaling

Abstract The extracellular matrix is a network of secreted macromolecules that provides a harmonious meshwork for the growth and homeostatic development of organisms. It conveys multiple signaling cascades affecting specific surface receptors that impact cell behavior. During cancer growth, this bioactive meshwork is remodeled and enriched in newly formed blood vessels, which provide nutrients and oxygen to the growing tumor cells. Remodeling of the tumor microenvironment leads to the formation of bioactive fragments that may have a distinct function from their parent molecules, and the balance among these factors directly influence cell viability and metastatic progression. Indeed, the matrix acts as a gatekeeper by regulating the access of cancer cells to nutrients. Here, we will critically evaluate the role of selected matrix constituents in regulating tumor angiogenesis and provide up-to-date information concerning their primary mechanisms of action.

The current role of gemcitabine in ovarian cancer

2001 ◽  
Vol 28 (2D) ◽  
pp. 18-24
Author(s):  
Robert F. Ozols
Keyword(s):  
Ovarian Cancer ◽  
Current Role

ROLE OF LIPID PROFILE IN OVARIAN CARCINOMA PATIENTS

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Dr. Manisha ◽  
Dr. Ruchi Jindal
Keyword(s):  
Ovarian Cancer ◽  
Lipid Profile ◽  
Cancer Patients ◽  
Ovarian Tumor ◽  
Ovarian Cancer Risk ◽  
Low Level ◽  
Medical College ◽  
Group I ◽  
History Of

Background: The term "ovarian cancer" includes several different types of cancer that  arise from cells of the ovary, most commonly, tumors arise from the epithelium or lining cells of the ovary.  Ovarian cancer risk is positively associated with higher consumption of dietary cholesterol and eggs, and inversely associated with a higher intake of vegetables. High consumption of fats may increase circulating estrogen levels, thus increasing the possibility of cell damage and proliferation that is responsible for cancerous growth. Material & Methods: The present study was conducted at Geetanjali Medical College and Hospital, Udaipur (Rajasthan). Total  100 cases (females) attending the obstetrics and gynecology department for some gynecological and other problem  were selected for this study between the age of 40-60 years, who were attending cancer centre at GEETANJALI MEDICAL COLLEGE AND  HOSPITAL, Udaipur (Rajasthan).                GROUP I: - It consisted of healthy females control subjects (n=50) .By routine examination and tests, we ensured that all the subjects were healthy and there were no signs and symptoms or history of ovarian tumor and diseases GROUP II: - It consisted of ovarian cancer females subjects (n=50) with a history of ovarian tumor. Results:   Higher level of cholesterol, LDL, VLDL and low level of HDL are found in ovarian cancer patients. Conclusion: The present study we highlights the importance and role of serum lipid profile in diagnosis, prognosis and recurrence of the disease. The study shows that serum level of cholesterol, LDL, VLDL was elevated in  patients of ovarian cancer while low level of HDL are found in ovarian cancer patients. Key words: lipid profile, ovarian cancer.

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