Role of a Novel Splice Variant of the Steroid Receptor Coactivator AIB1 in Breast Cancer

2002 ◽  
Author(s):  
Anna T. Riegel
Keyword(s):  
Breast Cancer ◽  
Splice Variant ◽  
Steroid Receptor ◽  
Steroid Receptor Coactivator

scholarly journals SRC-3, a Steroid Receptor Coactivator: Implication in Cancer

2021 ◽  
Vol 22 (9) ◽  
pp. 4760
Author(s):  
Licen Li ◽  
Chu-Xia Deng ◽  
Qiang Chen
Keyword(s):  
Breast Cancer ◽  
Transcription Factors ◽  
Cancer Therapy ◽  
Nuclear Receptors ◽  
Essential Role ◽  
Transcriptional Activity ◽  
Steroid Receptor ◽  
Steroid Receptor Coactivator ◽  
Important Progress

Steroid receptor coactivator-3 (SRC-3), also known as amplified in breast cancer 1 (AIB1), is a member of the SRC family. SRC-3 regulates not only the transcriptional activity of nuclear receptors but also many other transcription factors. Besides the essential role of SRC-3 in physiological functions, it also acts as an oncogene to promote multiple aspects of cancer. This review updates the important progress of SRC-3 in carcinogenesis and summarizes its mode of action, which provides clues for cancer therapy.

Abstract 2637: Role of d16HER2 splice variant in HER2-positive breast cancer

2014 ◽  
Author(s):  
Gaia C. Ghedini ◽  
Arianna Palladini ◽  
Valentina Ciravolo ◽  
Lorenzo Castagnoli ◽  
Giulia Marzano ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Splice Variant ◽  
Her2 Positive ◽  
Her2 Positive Breast Cancer ◽  
Positive Breast Cancer

Abstract B38: The role of BQ323636.1, a novel splice variant of NCOR2, in modulation of oxidative stress in breast cancer

2018 ◽  
Author(s):  
Man Hong Leung ◽  
Ho Tsoi ◽  
Ellen Pui Sum Man ◽  
Eric Wing-Fai Lam ◽  
Ui Soon Khoo
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Splice Variant
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