Microstructural Models of Interactions That Govern Protein Conformations: Algorithms for High Performance Computer Architectures

1998 ◽  
Author(s):  
Sangtae Kim
Keyword(s):  
High Performance ◽  
Computer Architectures ◽  
Protein Conformations ◽  
High Performance Computer

scholarly journals An object-oriented framework for valuing shout options on high-performance computer architectures

2003 ◽  
Vol 27 (6) ◽  
pp. 1133-1161 ◽  
Author(s):  
H. Windcliff ◽  
K.R. Vetzal ◽  
P.A. Forsyth ◽  
A. Verma ◽  
T.F. Coleman
Keyword(s):  
High Performance ◽  
Object Oriented ◽  
Computer Architectures ◽  
High Performance Computer

scholarly journals Fast nanopore sequencing data analysis with SLOW5

2022 ◽  
Author(s):  
Hasindu Gamaarachchi ◽  
Hiruna Samarakoon ◽  
Sasha P. Jenner ◽  
James M. Ferguson ◽  
Timothy G. Amos ◽  
...  
Keyword(s):  
Data Analysis ◽  
High Performance ◽  
Computer Architectures ◽  
Nanopore Sequencing ◽  
File Format ◽  
Sequencing Data ◽  
High Performance Computer ◽  
Sequencing Data Analysis ◽  
Efficient Parallelization ◽  
Methylation Profiling

AbstractNanopore sequencing depends on the FAST5 file format, which does not allow efficient parallel analysis. Here we introduce SLOW5, an alternative format engineered for efficient parallelization and acceleration of nanopore data analysis. Using the example of DNA methylation profiling of a human genome, analysis runtime is reduced from more than two weeks to approximately 10.5 h on a typical high-performance computer. SLOW5 is approximately 25% smaller than FAST5 and delivers consistent improvements on different computer architectures.

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