Retrospective Study of HIV Infection in Human Tissues. Computer Survey of the AFIP Repository for Cases of Acquired Immunodeficiency Preceding the HIV Pandemic

1994 ◽  
Author(s):  
Ann M. Nelson ◽  
Albin Moroz ◽  
Florabel G. Mullick ◽  
William R. Rohland ◽  
Joyce C. Manus
Keyword(s):  
Retrospective Study ◽  
Hiv Infection ◽  
Human Tissues ◽  
Acquired Immunodeficiency

Retrospective Study of HIV Infection in Human Tissues

1993 ◽  
Author(s):  
Ann M. Nelson ◽  
Adolfo Firpo ◽  
Florabel G. Mullick ◽  
Patrick E. Lorenz ◽  
William R. Rohland
Keyword(s):  
Retrospective Study ◽  
Hiv Infection ◽  
Human Tissues

Bacillary Angiomatosis: A Unique Cutaneous Complication of Hiv Infection

1995 ◽  
Vol 3 (2) ◽  
pp. 1-10
Author(s):  
Joan Lipa ◽  
Walter Peters ◽  
Victor Fornasier ◽  
Benjamin Fisher
Keyword(s):  
Hiv Infection ◽  
Definitive Diagnosis ◽  
Causal Organism ◽  
Bacillary Angiomatosis ◽  
Immunodeficiency Virus ◽  
Confirmatory Tests ◽  
Nodular Lesions ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Erythromycin Therapy

As the prevalence of human immunodeficiency virus (HIV) infection increases, so does the recognition of unusual manifestations of this syndrome. This study describes two patients who presented with a unique, rare, cutaneous manifestion of HIV infection. One patient developed an aggressive atypical cellulitis and ascending lymphangitis of the hand, which failed to improve following multiple courses of several different antibiotics. The other patient presented with multiple, vascular, nodular lesions, clinically resembling Kaposi's sarcoma. Routine biopsies and wound cultures were not helpful for diagnosis. A definitive diagnosis of bacillary angiomatosis (BA) was made using a special silver-staining (Warthin-Starry) histological technique and electron microscopy. Both patients responded completely to oral erythromycin therapy. BA is a newly recognized bacterial infection caused by bacteria of the genus Bartonella. It is seen primarily in patients with acquired immunodeficiency syndrome (AIDS), and less commonly in patients with other immunosuppressed conditions. The term BA describes the lesion's pathogenesis (infective-bacillary) and clinico-histology (angiomatosis). The causal organism cannot be cultured reliably and is resistant to most antibiotics. This study reviews these two patients, the differential diagnosis of BA, specific confirmatory tests used in diagnosis, and the treatment outcome of this condition. It is important for the plastic surgeon to understand BA, because it can resemble other common presentations, but it can also be associated with internal involvement leading to mortality. However, when recognized, it can usually be cured by oral erythromycin therapy (500 mg qid) for several weeks.

Decreased Thymus Size on Chest Radiography: A Sign of Pediatric Human Immunodeficiency Virus Infection?

PEDIATRICS ◽  
1992 ◽  
Vol 90 (1) ◽  
pp. 99-102
Author(s):  
ALAN MEYERS ◽  
NICHOLAS PEPE ◽  
WILLIAM CRANLEY ◽  
KATHLEEN MCCARTEN
Keyword(s):  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Chest Radiography ◽  
Pediatric Hiv ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Acquired Immunodeficiency ◽  
Generalized Lymphadenopathy ◽  
Immunodeficiency Syndrome ◽  
Thymus Size

The early diagnosis of infection with the human immunodeficiency virus (HIV) in infancy is clinically important but remains problematic in the asymptomatic child born to an HIV-infected mother. In addition, many such women are unaware of their HIV infection until their child manifests symptomatic HIV disease. Nonspecific signs of pediatric HIV infection, such as generalized lymphadenopathy, hepatosplenomegaly, or persistent thrush, may be important in alerting the clinician to consider the possibility of HIV infection in the child whose history of HIV risk is unknown. We report one such sign which may be evident on plain chest radiography. The pathology of the thymus gland in pediatric acquired immunodeficiency syndrome has been described by Joshi and colleagues,1-3 who have reported precocious involution with marked reduction in thymus size and weight.

Pediatric Acquired Immunodeficiency Syndrome: An Unusually High Incidence of Twinning

PEDIATRICS ◽  
1990 ◽  
Vol 86 (5) ◽  
pp. 774-777
Author(s):  
PAULINE A. THOMAS ◽  
STEVEN J. RALSTON ◽  
MARIE BERNARD ◽  
ROSALYN WILLIAMS ◽  
RITA O'DONNELL
Keyword(s):  
New York ◽  
New York City ◽  
Hiv Infection ◽  
York City ◽  
Acquired Immunodeficiency Syndrome ◽  
Early Years ◽  
Pediatric Aids ◽  
High Incidence ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome

Surveillance data on incidence of twins among reported cases of pediatric AIDS in New York City are presented. Most pairs are concordant for HIV infection. Three discordant pairs have been described elsewhere. Possible reasons for the association are discussed, including the most likely explanation that twins show symptoms early and are overrepresented in the early years of surveillance of pediatric AIDS.

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