Correlation of the Vocal Fold Vibratory Pattern to the Post-Operative Surgical Wound in the Porcine Model.

1992 ◽  
Author(s):  
Donald B. Blakeslee ◽  
Ronald Banks ◽  
Vincent D. Eusterman ◽  
Daniel Brooks
Keyword(s):  
Vocal Fold ◽  
Porcine Model ◽  
Surgical Wound ◽  
Vibratory Pattern

Vocal fold injury following endotracheal intubation

2005 ◽  
Vol 119 (10) ◽  
pp. 825-827 ◽  
Author(s):  
Satoshi Kitahara ◽  
Yukihiro Masuda ◽  
Yoko Kitagawa
Keyword(s):  
Endotracheal Intubation ◽  
Fibrin Glue ◽  
Vocal Fold ◽  
Case Reports ◽  
Voice Quality ◽  
Fibrous Tissue ◽  
Normal Result ◽  
Perceptual Evaluation ◽  
Vibratory Pattern

Vocal fold scarring results in the formation of fibrous tissue which disturbs the vibratory pattern of the fold during phonation. However, vocal fold scarring in humans is poorly understood because of the lack of clear case reports focusing on voice quality. The authors present a case of vocal fold scarring with changes in voice quality. At the time of injury the pedicle mucosa was cemented with fibrin glue. Phonation was inhibited for two weeks and tranilast (300 mg/day) was given for 3 months. Sixty-nine days later, perceptual evaluation showed a normal result and the phonation time became better, but the mucosal vibration was still lacking. Ninety-seven days later, mucosal vibration was finally restored. We suggest that characterization of vocal fold scarring in humans may be different from that in animals, and recommend that surgical management should be avoided for at least three months after injury.

Reflex Vocal Fold Adduction in the Porcine Model: The Effects of Stimuli Delivered to Various Sensory Nerves

2008 ◽  
Vol 117 (10) ◽  
pp. 749-752 ◽  
Author(s):  
Jeong-Soo Woo ◽  
Jagdeep S. Hundal ◽  
Clarence T. Sasaki ◽  
Mikhail W. Abdelmessih ◽  
Stephen P. Kelleher
Keyword(s):  
Vocal Fold ◽  
Porcine Model ◽  
Superior Laryngeal Nerve ◽  
Sensory Nerves ◽  
Internal Branch ◽  
Pharyngeal Plexus ◽  
Closing Force ◽  
Intercostal Nerves ◽  
Glottic Closure Reflex ◽  
Stimulation Of

Objectives: The aim of this study was to identify a panel of sensory nerves capable of eliciting an evoked glottic closure reflex (GCR) and to quantify the glottic closing force (GCF) of these responses in a porcine model. Methods: In 5 pigs, the internal branch of the superior laryngeal nerve (iSLN) and the trigeminal, pharyngeal plexus, glossopharyngeal, radial, and intercostal nerves were surgically isolated and electrically stimulated. During stimulation of each nerve, the GCR was detected by laryngeal electromyography and the GCF was measured with a pressure transducer. Results: The only nerve that elicited the GCR in the 5 pigs was the iSLN. The average GCF was 288.9 mm Hg. Conclusions: This study demonstrates that the only afferent nerve that elicits the GCR in pigs is the iSLN, and that it should remain the focus of research for the rehabilitation of patients with absent or defective reflex vocal fold adduction.

scholarly journals Typing Vocal Fold Vibratory Patterns in Excised Larynx Experiments Via Digital Kymography

2009 ◽  
Vol 118 (8) ◽  
pp. 598-605 ◽  
Author(s):  
Yu Zhang ◽  
Christopher R. Krausert ◽  
Michael P. Kelly ◽  
Jack J. Jiang
Keyword(s):  
Time Series ◽  
Frequency Spectrum ◽  
Direct Observation ◽  
Vocal Fold ◽  
Video Data ◽  
Signal Type ◽  
Vibratory Pattern ◽  
Type 3

Objectives Signal typing is central to the understanding of vocal fold vibratory patterns. Digital kymography (DKG) allows the direct observation of vocal fold vibratory patterns, and therefore, using DKG for vibratory signal typing may provide a useful complement to traditional signal typing techniques. Methods Video data collected from 20 larynges excised from mongrel dogs were observed with DKG in order to find examples of type 1 (nearly periodic), type 2 (subharmonic), and type 3 (aperiodic) vibratory patterns. The time series, frequency spectra, and correlation dimensions were calculated for each signal type. Results The type 1 pattern showed a periodic time series of glottal edges and a discrete frequency spectrum. The type 2 vibratory pattern displayed a time series of alternating high- and low-amplitude waves and a frequency spectrum that included a subharmonic (F0/2) frequency component. Regular and symmetric vibratory patterns were observed in the type 1 and type 2 patterns. The type 3 vibratory pattern was characterized by an aperiodic time series of glottal edges, a broadband frequency spectrum, and irregular and asymmetric vibratory patterns. The correlation dimension estimates increased from type 1 to type 2 to type 3. Conclusions Imaging with DKG demonstrated an ability to assign a signal type to various laryngeal vibrations. Signal typing techniques utilizing direct observation of the vocal folds could be useful in determining valid methods for the analysis of vocal fold vibrations.

scholarly journals The effects of decorin and HGF-primed vocal fold fibroblasts in vitro and ex vivo in a porcine model of vocal fold scarring

2010 ◽  
Vol 120 (11) ◽  
pp. 2247-2257 ◽  
Author(s):  
Priya Krishna ◽  
Michael Regner ◽  
Joel Palko ◽  
Fang Liu ◽  
Steve Abramowitch ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Porcine Model ◽  
Ex Vivo

Spindle-Shaped Glottal Insufficiency with and without Sulcus Vocalis: A Retrospective Study

1994 ◽  
Vol 103 (7) ◽  
pp. 547-553 ◽  
Author(s):  
Per-Åke Lindestad ◽  
Stellan Hertegård
Keyword(s):  
Retrospective Study ◽  
Vocal Fold ◽  
Voice Change ◽  
Physical Ability ◽  
Clinical Background ◽  
History Of ◽  
Glottal Insufficiency ◽  
Sulcus Vocalis ◽  
Vibratory Pattern ◽  
Clinical Records

The clinical records of 186 patients with spindle-shaped glottal insufficiency were studied in order to evaluate the clinical background of the finding. The patients formed two main groups: those with and those without sulcus vocalis. Most of the sulcus patients were females, comparatively young at the onset of symptoms and at the time of diagnosis. In contrast, the majority of patients with spindle-shaped glottal insufficiency without sulcus were male and they often had a history of either laryngitis or chronic general disease causing decreased physical ability. Some patients in this group had long-standing symptoms, possibly caused by a disturbance in pubertal voice change. The data also indicate differences between the groups in vocal fold vibratory pattern. It is evident that the spindle-shaped glottal insufficiency observed in patients with and without sulcus has different causes and different pathophysiologic explanations.

Microvascular Lesions of the True Vocal Fold

1998 ◽  
Vol 107 (6) ◽  
pp. 472-476 ◽  
Author(s):  
Gregory N. Postma ◽  
Mark S. Courey ◽  
Robert H. Ossoff
Keyword(s):  
Medical Therapy ◽  
Functional Significance ◽  
Vocal Fold ◽  
Speech Therapy ◽  
Vocal Folds ◽  
Indications For Surgery ◽  
Recurrent Hemorrhage ◽  
Polyp Formation ◽  
Vibratory Pattern ◽  
Repetitive Trauma

Microvascular lesions, also called varices or capillary ectasias, in contrast to vocal fold polyps with telangiectatic vessels, are relatively small lesions arising from the microcirculation of the vocal fold. Varices are most commonly seen in female professional vocalists and may be secondary to repetitive trauma, hormonal variations, or repeated inflammation. Microvascular lesions may either be asymptomatic or cause frank dysphonia by interrupting the normal vibratory pattern, mass, or closure of the vocal folds. They may also lead to vocal fold hemorrhage, scarring, or polyp formation. Laryngovideostroboscopy is the key in determining the functional significance of vocal fold varices. Management of patients with a varix includes medical therapy, speech therapy, and occasionally surgical vaporization. Indications for surgery are recurrent hemorrhage, enlargement of the varix, development of a mass in conjunction with the varix or hemorrhage, and unacceptable dysphonia after maximal medical and speech therapy due to a functionally significant varix.

Effect of high-dose vocal fold injection of cidofovir and bevacizumab in a porcine model

2016 ◽  
Vol 127 (3) ◽  
pp. 671-675 ◽  
Author(s):  
Mostafa. M. Ahmed ◽  
Matthew. P. Connor ◽  
Mitzi Palazzolo ◽  
Michelle E. Thompson ◽  
Josh Lospinoso ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Porcine Model ◽  
High Dose ◽  
Vocal Fold Injection

scholarly journals Effect of Vocal Fold Injection of Cidofovir and Bevacizumab in a Porcine Model

2014 ◽  
Vol 140 (2) ◽  
pp. 155 ◽  
Author(s):  
Matthew P. Connor ◽  
Ammon Brown ◽  
Mitzi Palazzolo ◽  
Julie Kunkel ◽  
Robert Eller ◽  
...  
Keyword(s):  
Vocal Fold ◽  
Porcine Model ◽  
Vocal Fold Injection
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