Flight Simulator Maintenance Training: Potential Use of State-of-the-Art Simulation Techniques.

1979 ◽  
Author(s):  
Charles F. M. Condon ◽  
Lawrence L. Ames ◽  
John R. Hennessy ◽  
Edgar L. Shriver ◽  
Russell E. Seeman
Keyword(s):  
State Of The Art ◽  
Flight Simulator ◽  
Simulation Techniques ◽  
Potential Use

State of the Art on Carbonic Anhydrase Modulators for Biomedical Purposes

2019 ◽  
Vol 26 (15) ◽  
pp. 2558-2573 ◽  
Author(s):  
Murat Bozdag ◽  
Abdulmalik Saleh Alfawaz Altamimi ◽  
Daniela Vullo ◽  
Claudiu T. Supuran ◽  
Fabrizio Carta
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
State Of The Art ◽  
Cellular Level ◽  
Hydration Reaction ◽  
Carbonic Anhydrases ◽  
Crucial Importance ◽  
Learning Impairments ◽  
Current Review ◽  
Potential Use

The current review is intended to highlight recent advances in the search of new and effective modulators of the metalloenzymes Carbonic Anhydrases (CAs, EC 4.2.1.1) expressed in humans (h). CAs reversibly catalyze the CO2 hydration reaction, which is of crucial importance in the regulation of a plethora of fundamental processes at cellular level as well as in complex organisms. The first section of this review will be dedicated to compounds acting as activators of the hCAs (CAAs) and their promising effects on central nervous system affecting pathologies mainly characterized from memory and learning impairments. The second part will focus on the emerging chemical classes acting as hCA inhibitors (CAIs) and their potential use for the treatment of diseases.

Neither Eyewitnesses, Nor Windows to the Past, but Valuable Testimony in its Own Right: Remarks on Iconography, Source Criticism and Ancient Data-processing

2007 ◽  
Author(s):  
CHRISTOPH UEHLINGER
Keyword(s):  
Data Processing ◽  
Conceptual Framework ◽  
Visual Art ◽  
State Of The Art ◽  
Case Examples ◽  
The Past ◽  
Ancient Israel ◽  
History Of ◽  
Alternative Approaches ◽  
Potential Use

This chapter explores the potential use of visual sources, together with the methods employed for studying them, such as iconography or iconology, for the history of ‘ancient Israel’. It describes the theoretical and conceptual framework, particularly the notion of ‘eyewitnessing’, and considers the method, particularly iconography. The chapter also presents case examples chosen from monuments which are so well known to historians of ancient Israel that they are well suited to illustrate both the pitfalls of more conventional interpretations and the potential of alternative approaches. Before turning to the sources – namely visual evidence that may be related to the history of ancient Israel and Judah – the chapter discusses the state of the art among fellow historians in neighbouring disciplines, including those belonging to the so-called ‘humanities’ (or arts and letters). It also considers visual art and history, the metaphor of legal investigation, the balancing of testimony, and the particular status of an eyewitness.

scholarly journals RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic models

2019 ◽  
Author(s):  
Cheng Zhang ◽  
Sunjae Lee ◽  
Gholamreza Bidkhori ◽  
Rui Benfeitas ◽  
Alen Lovric ◽  
...  
Keyword(s):  
Case Studies ◽  
State Of The Art ◽  
Differentially Expressed ◽  
Systems Medicine ◽  
Transcriptomics Data ◽  
Altered Metabolism ◽  
Metabolic Models ◽  
Genome Scale ◽  
Potential Use ◽  
Single Set

AbstractRelative Metabolic Differences version 2 (RMetD2) is a tool for integration of differentially expressed (DE) genes into genome-scale metabolic models (GEMs) for revealing the altered metabolism between two biological conditions. This method provides a robust evaluation of the metabolism by using flux ranges instead of a single set of flux distributions. RMetD2 classifies reactions into three different groups, namely up-regulated, down-regulated and unchanged, which enables systematic interpretation of the metabolic differences between two different conditions. We employed this method in three different case studies using mice and human datasets, and compared it with state-of-the-art methods used for studying condition-specific metabolic differences using GEMs. We observed that RMetD2 is capable of capturing experimentally-observed features that are missed by other methods, highlighting its potential use in biotechnology and systems medicine applications. RMetD2 is implemented in Matlab and it is available without any limitation at https://sourceforge.net/projects/rmetd.

scholarly journals Study of light nuclei by polarization observables in electron scattering

2020 ◽  
Author(s):  
Simon Sirca
Keyword(s):  
Magnetic Properties ◽  
Electron Scattering ◽  
Spin Structure ◽  
State Of The Art ◽  
Light Nuclei ◽  
Knock Out ◽  
Polarized Beams ◽  
Simulation Techniques ◽  
Dynamical Properties ◽  
Electro Magnetic

Electron-induced proton, neutron and deuteron knock-out remains the most versatile probe of the electro-magnetic properties and spin structure of light nuclei. The advent of highly polarized beams and targets and improvements in recoil polarization methods, as well as analysis and simulation techniques, have enabled us to study the static and dynamical properties of few-body systems with unprecedented precision. Recent experiments at Jefferson Lab and MAMI are presented and put into perspective of state-of-the art Faddeev calculations, with focus on the ^\mathbf{3}\mathbf{He}3𝐇𝐞 nucleus.

Review : Bacteriocinogenic lactic acid bacteria associated with meat products / Revisión: Bacterias lácticas productoras de bacteriocinas asociadas a productos cárnicos

1998 ◽  
Vol 4 (3) ◽  
pp. 141-158 ◽  
Author(s):  
M.T. Aymerich ◽  
M. Hugas ◽  
J.M. Monfort
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
State Of The Art ◽  
Meat Products ◽  
Meat Consumption ◽  
Genetic Characteristics ◽  
Current State ◽  
Potential Use

Meat consumption is of great economical importance. Several lactic acid bacteria associated with meat products are important natural bacteriocin producers. Bacteriocins are proteinaceous antag onistic substances considered to be important in the control of spoilage and pathogenic microor ganisms. This review aims to present the current state of the art in terms of bacteriocinogenic lactic acid bacteria associated with fresh and fermented meat products, describe the biochemical and genetic characteristics of their bacteriocins and the potential use of bacteriocins production of meat products.

scholarly journals Simulation in psychiatric teaching

2012 ◽  
Vol 18 (4) ◽  
pp. 292-298 ◽  
Author(s):  
Subodh Dave
Keyword(s):  
Learning Experience ◽  
Simulated Patients ◽  
Teaching Skills ◽  
Psychiatric Education ◽  
Advantages And Disadvantages ◽  
Simulation Techniques ◽  
Objective Structured Clinical Examinations ◽  
Cost Implications ◽  
Potential Use ◽  
Specific Learning

SummaryThe use of simulated patients in medicine offers students a standardised learning experience and a reproducible way of exploring attitudes and teaching communication skills. This would seem to be particularly relevant to psychiatry with its focus on attitudes and interpersonal skills, but doubts have been raised about the utility of simulated patients in teaching skills such as empathy and the generalisability of this learning to the real world. This, tempered with cost implications, may have limited the use of simulated patients to assessment through objective structured clinical examinations rather than to teaching and to learning. This article examines the educational advantages and disadvantages of the use of simulated patients in psychiatric teaching and argues that their judicious use complements undergraduate and postgraduate training in psychiatry. The article offers practical tips on writing simulated patient scenarios to deliver specific learning objectives and discusses the potential use of novel simulation techniques in psychiatric education.

scholarly journals Haloarchaea as Cell Factories to Produce Bioplastics

Marine Drugs ◽  
2021 ◽  
Vol 19 (3) ◽  
pp. 159
Author(s):  
Lorena Simó-Cabrera ◽  
Salvador García-Chumillas ◽  
Nashwa Hagagy ◽  
Amna Saddiq ◽  
Hend Tag ◽  
...  
Keyword(s):  
State Of The Art ◽  
Industrial Scale ◽  
Design Strategies ◽  
Plastic Pollution ◽  
Plastic Recycling ◽  
Cell Factories ◽  
Environmental Deterioration ◽  
New Research ◽  
Potential Use ◽  
Shed Light

Plastic pollution is a worldwide concern causing the death of animals (mainly aquatic fauna) and environmental deterioration. Plastic recycling is, in most cases, difficult or even impossible. For this reason, new research lines are emerging to identify highly biodegradable bioplastics or plastic formulations that are more environmentally friendly than current ones. In this context, microbes, capable of synthesizing bioplastics, were revealed to be good models to design strategies in which microorganisms can be used as cell factories. Recently, special interest has been paid to haloarchaea due to the capability of some species to produce significant concentrations of polyhydroxyalkanoate (PHA), polyhydroxybutyrate (PHB), and polyhydroxyvalerate (PHV) when growing under a specific nutritional status. The growth of those microorganisms at the pilot or industrial scale offers several advantages compared to that of other microbes that are bioplastic producers. This review summarizes the state of the art of bioplastic production and the most recent findings regarding the production of bioplastics by halophilic microorganisms with special emphasis on haloarchaea. Some protocols to produce/analyze bioplastics are highlighted here to shed light on the potential use of haloarchaea at the industrial scale to produce valuable products, thus minimizing environmental pollution by plastics made from petroleum.

scholarly journals Magnetotactic Bacteria and Magnetosomes: Basic Properties and Applications

2021 ◽  
Vol 7 (6) ◽  
pp. 86
Author(s):  
Kamil G. Gareev ◽  
Denis S. Grouzdev ◽  
Petr V. Kharitonskii ◽  
Andrei Kosterov ◽  
Veronika V. Koziaeva ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Rock Magnetism ◽  
Magnetotactic Bacteria ◽  
Resonance Imaging ◽  
Current State ◽  
Magnetite Fe3o4 ◽  
High Degree ◽  
Potential Use

Magnetotactic bacteria (MTB) belong to several phyla. This class of microorganisms exhibits the ability of magneto-aerotaxis. MTB synthesize biominerals in organelle-like structures called magnetosomes, which contain single-domain crystals of magnetite (Fe3O4) or greigite (Fe3S4) characterized by a high degree of structural and compositional perfection. Magnetosomes from dead MTB could be preserved in sediments (called fossil magnetosomes or magnetofossils). Under certain conditions, magnetofossils are capable of retaining their remanence for millions of years. This accounts for the growing interest in MTB and magnetofossils in paleo- and rock magnetism and in a wider field of biogeoscience. At the same time, high biocompatibility of magnetosomes makes possible their potential use in biomedical applications, including magnetic resonance imaging, hyperthermia, magnetically guided drug delivery, and immunomagnetic analysis. In this review, we attempt to summarize the current state of the art in the field of MTB research and applications.

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