BIOENGINEERING STUDY ON THE NATURE AND FUNCTION OF THE HUMAN CARDIOVASCULAR SYSTEM

1969 ◽  
Author(s):  
II Hoppmann ◽  
W. H.
Keyword(s):  
Cardiovascular System ◽  
Human Cardiovascular System ◽  
And Function

Bifurcation in a Simple Model of the Cardiovascular System

2000 ◽  
Vol 39 (02) ◽  
pp. 118-121 ◽  
Author(s):  
S. Akselrod ◽  
S. Eyal
Keyword(s):  
Nonlinear Dynamics ◽  
Blood Pressure ◽  
Heart Rate ◽  
Fixed Point ◽  
Cardiovascular System ◽  
Modified Model ◽  
Mayer Waves ◽  
Sustained Oscillations ◽  
Human Cardiovascular System ◽  
Physiological Values

Abstract:A simple nonlinear beat-to-beat model of the human cardiovascular system has been studied. The model, introduced by DeBoer et al. was a simplified linearized version. We present a modified model which allows to investigate the nonlinear dynamics of the cardiovascular system. We found that an increase in the -sympathetic gain, via a Hopf bifurcation, leads to sustained oscillations both in heart rate and blood pressure variables at about 0.1 Hz (Mayer waves). Similar oscillations were observed when increasing the -sympathetic gain or decreasing the vagal gain. Further changes of the gains, even beyond reasonable physiological values, did not reveal another bifurcation. The dynamics observed were thus either fixed point or limit cycle. Introducing respiration into the model showed entrainment between the respiration frequency and the Mayer waves.

Extracellular vesicle interplay in cardiovascular pathophysiology

2021 ◽  
Author(s):  
Sherin Saheera ◽  
Vivek P Jani ◽  
Kenneth W Witwer ◽  
Shelby Kutty
Keyword(s):  
Plasma Membrane ◽  
Cardiovascular System ◽  
Lipid Bilayer ◽  
Cellular Responses ◽  
Extracellular Vesicle ◽  
Cargo Proteins ◽  
And Function ◽  
Intercellular Communications ◽  
Rna And Dna

Extracellular vesicles (EVs) are nanosized lipid bilayer-delimited particles released from cells that mediate intercellular communications and play a pivotal role in various physiological and pathological processes. Subtypes of EVs may include plasma-membrane ectosomes or microvesicles and endosomal-origin exosomes, although functional distinctions remain unclear. EVs carry cargo proteins, nucleic acids (RNA and DNA), lipids, and metabolites. By presenting or transferring this cargo to recipient cells, EVs can trigger cellular responses. Here, we summarize what is known about EV biogenesis, composition, and function, with an emphasis on the role of EVs in cardiovascular system. Additionally, we provide an update on the function of EVs in cardiovascular pathophysiology, further highlighting their potential for diagnostic and therapeutic applications.

scholarly journals A Novel Patient-Specific Human Cardiovascular System Phantom (HCSP) for Reconstructions of Pulsatile Blood Hemodynamic Inside Abdominal Aortic Aneurysm

IEEE Access ◽  
2018 ◽  
Vol 6 ◽  
pp. 61896-61903 ◽  
Author(s):  
Andrzej Polanczyk ◽  
Michal Podgorski ◽  
Maciej Polanczyk ◽  
Aleksandra Piechota-Polanczyk ◽  
Christoph Neumayer ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Cardiovascular System ◽  
Patient Specific ◽  
Abdominal Aortic ◽  
Human Cardiovascular System

scholarly journals Digital subtraction angiography of the human cardiovascular system

1980 ◽  
Vol 135 (6) ◽  
pp. 1153-1160 ◽  
Author(s):  
TF Meaney ◽  
MA Weinstein ◽  
E Buonocore ◽  
W Pavlicek ◽  
GP Borkowski ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Digital Subtraction Angiography ◽  
Digital Subtraction ◽  
Human Cardiovascular System

Synchronization of low-frequency oscillations in the human cardiovascular system

2009 ◽  
Vol 19 (3) ◽  
pp. 033112 ◽  
Author(s):  
A. S. Karavaev ◽  
M. D. Prokhorov ◽  
V. I. Ponomarenko ◽  
A. R. Kiselev ◽  
V. I. Gridnev ◽  
...  
Keyword(s):  
Cardiovascular System ◽  
Low Frequency ◽  
Low Frequency Oscillations ◽  
Human Cardiovascular System

scholarly journals The effect of mirthful laughter on the human cardiovascular system

2009 ◽  
Vol 73 (5) ◽  
pp. 636-639 ◽  
Author(s):  
Michael Miller ◽  
William F. Fry
Keyword(s):  
Cardiovascular System ◽  
Human Cardiovascular System
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