SIMULATION OF CHEMILUMINESCENT REACTION OF NITRIC OXIDE WITH ATOMIC OXYGEN IN A SUPERSONIC LOW DENSITY WIND TUNNEL, PART 2

1967 ◽  
Author(s):  
Jan A. van der Bliek ◽  
Robert A. Cassanova
Keyword(s):  
Nitric Oxide ◽  
Wind Tunnel ◽  
Atomic Oxygen ◽  
Low Density ◽  
Chemiluminescent Reaction

NO–O Chemiluminescent Reaction in a Low‐Density Wind Tunnel

1966 ◽  
Vol 44 (11) ◽  
pp. 4349-4350 ◽  
Author(s):  
F. P. DelGreco ◽  
D. Golomb ◽  
J. A. van der Bliek ◽  
R. A. Cassanova ◽  
R. E. Good
Keyword(s):  
Wind Tunnel ◽  
Low Density ◽  
Chemiluminescent Reaction

scholarly journals Oxidized Low Density Lipoproteins Alter Macrophage Lipid Uptake, Apoptosis, Viability and Nitric Oxide Synthesis

1996 ◽  
Vol 126 (suppl_4) ◽  
pp. 1072S-1075S ◽  
Author(s):  
Xiaochun Yang ◽  
Narmer F. Galeano ◽  
Matthias Szabolcs ◽  
Robert R. Sciacca ◽  
Paul J. Cannon
Keyword(s):  
Nitric Oxide ◽  
Low Density Lipoproteins ◽  
Low Density ◽  
Nitric Oxide Synthesis ◽  
Lipid Uptake ◽  
Oxidized Low Density Lipoproteins

Effects of lipoproteins from pre-eclamptic women on umbilical endothelial cell 6-oxo-prostaglandin F1α and endothelin 1 synthesis, and nitric oxide synthase 3 mRNA expression

1999 ◽  
Vol 97 (6) ◽  
pp. 697-706 ◽  
Author(s):  
A. BARDEN ◽  
L. J. BEILIN ◽  
K. BOTH ◽  
J. RITCHIE ◽  
P. LEEDMAN ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cell ◽  
Nitric Oxide Synthase ◽  
Pregnant Women ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Endothelin 1 ◽  
Nitric Oxide Synthase 3 ◽  
Oxide Synthase

In order to evaluate whether lipid abnormalities may contribute to endothelial dysfunction in pre-eclampsia, the present study examined the in vitro effects of very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL), isolated from women with pre-eclampsia and matched controls, on the endothelial synthesis of 6-oxo-prostaglandin F1α (6-oxo-PGF1α; a metabolite of prostacyclin) and endothelin 1, and on the expression of nitric oxide synthase 3 (NOS3) mRNA. VLDL, LDL and HDL cholesterol were isolated from 20 pre-eclamptic and 20 age- and gestation-matched normal pregnant women. The lipoproteins (50 μg/ml) and lipoprotein-free control plasma were incubated for 1, 3 and 6 h at 37 °C with a human umbilical endothelial cell line. The synthesis of 6-oxo-PGF1α and endothelin 1, and NOS3 mRNA expression, were measured at each time point. VLDL from pre-eclamptic women stimulated endothelial cell 6-oxo-PGF1α synthesis to a lesser extent than that from normal pregnant women (P< 0.05). LDL from women with pre-eclampsia also stimulated 6-oxo-PGF1α synthesis to a lesser extent than LDL from normal pregnant women, but the effect was less sustained. The effect of HDL from women with pre-eclampsia on 6-oxo-PGF1α synthesis was similar to that of HDL from normal pregnant women. The pre-incubation levels of lipid peroxides in VLDL and LDL were not different between the normal pregnant and pre-eclamptic women, and cannot account for the decrease in 6-oxo-PGF1α synthesis. VLDL, LDL and HDL from women with pre-eclampsia did not affect endothelial cell synthesis of endothelin 1 or expression of NOS3 mRNA differently from lipoproteins from normal pregnant women. This study suggests that VLDL, and to a lesser extent LDL, from women with pre-eclampsia could potentially contribute to the reduced systemic 6-oxo-PGF1α synthesis observed in the pre-eclamptic syndrome.

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