scholarly journals Socioeconomic status of pregnancy outcomes in Chongqing, Southwest China

2019 ◽  
Author(s):  
Ting Zhang ◽  
Wei Zhou ◽  
Qiang Tan ◽  
Ping Tang ◽  
Tao Kuang ◽  
...  

Abstract Background: Findings of socioeconomic status (SES) effects on adverse pregnancy outcomes varies depending on pregnancy complications, SES indicators, countries, regions, and races. Our aim was to compare three SES indicators (maternal educational level, participant and partner’s income and maternal occupation) and to investigate the relationship with adverse pregnancy outcomes in Chongqing, Southwest China. Methods: Between 2015 and 2017, we analyzed data from 1273 women in Chongqing, China, enrolled in the Complex Lipids in Mothers and Babies (CLIMB) trial in which mothers received complex lipid supplementation during pregnancy. Information on SES (maternal educational level, participant and partner’s income and maternal occupation) was collected during face-to-face interviews using standard questionnaires. Pregnancy outcomes considered were gestational diabetes mellitus (GDM), premature rupture of membrane (PROM), cesarean section (C-section), preterm birth (PTB), macrosomia, low birth weight (LBW), large for gestational age (LGA), and small for gestational age (SGA). Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for pregnancy outcomes in relation to SES. Supplementation had no effect on pregnancy outcomes, so our analysis did not subdivide our participants on this basis. Results: Women who were managers or professionals were less likely to suffer from macrosomia and LGA. After adjustment for potential confounders, the ORs for macrosomia and LGA were 0.44 (95% CI: 0.21, 0.95) and 0.48 (95% CI: 0.26, 0.89), respectively. Other pregnancy outcomes were not affected by maternal occupation. Moreover, no significant relationships were observed between the other two SES indicators (participant and partner’s income and maternal education) and adverse pregnancy outcomes. Conclusions: Our findings suggested that maternal occupation was a more reliable predictor of pregnancy outcomes than maternal education and participant and partner’s income.

2019 ◽  
Author(s):  
Ting Zhang ◽  
Wei Zhou ◽  
Qiang Tan ◽  
Ping Tang ◽  
Tao Kuang ◽  
...  

Abstract Background: The relationship between socioeconomic status (SES) and pregnancy outcomes has rarely been studied in Southwest China. Our aim was to investigate whether SES was associated with the risk of adverse pregnancy outcomes. Methods: Between 2015 and 2017, we analyzed data from 1273 women in Chongqing, China, enrolled in the Complex Lipids in Mothers and Babies (CLIMB) trial in which mothers received complex lipid supplementation during pregnancy. Information on SES (maternal educational level, participant and partner’s income and maternal occupation) was collected during face-to-face interviews using standard questionnaires. Pregnancy outcomes considered were gestational diabetes mellitus (GDM), premature rupture of membrane (PROM), cesarean section (C-section), preterm birth (PTB), macrosomia, low birth weight (LBW), large for gestational age (LGA), and small for gestational age (SGA). Logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for pregnancy outcomes in relation to SES. Supplementation had no effect on pregnancy outcomes, so our analysis did not subdivide our participants on this basis. Results: Women who were managers or professionals were less likely to suffer from macrosomia and LGA. After adjustment for potential confounders, the ORs for macrosomia and LGA were 0.44 (95% CI: 0.21, 0.95) and 0.48 (95% CI: 0.26, 0.89), respectively. Other pregnancy outcomes were not affected by maternal occupation. Moreover, no significant relationships were observed between the other two SES indicators (participant and partner’s income and maternal education) and adverse pregnancy outcomes. Conclusions: Our findings suggested that maternal occupation was a more reliable predictor of pregnancy outcomes than maternal education and participant and partner’s income.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yue Chen ◽  
Ke Wan ◽  
Yunhui Gong ◽  
Xiao Zhang ◽  
Yi Liang ◽  
...  

AbstractThe relevance of pregestational body mass index (BMI) on adverse pregnancy outcomes remained unclear in Southwest China. This study aimed to investigate the overall and age-category specific association between pre-gestational BMI and gestational diabetes mellitus (GDM), preeclampsia, cesarean delivery, preterm delivery, stillbirth, macrosomia, and small-for-gestational age (SGA) or large-for-gestational age (LGA) neonates in Southwest China. Furthermore, it explores the relative importance of influence of pregravid BMI and maternal age on pregnancy outcomes. 51,125 Chinese singleton pregnant women were recruited as study subjects. Multiple logistic regression models were used to examine the influence of pre-pregnancy BMI on adverse pregnancy outcomes. Gradient boosting machine was used to evaluate the relative importance of influence of pregravid BMI and maternal age on pregnancy outcomes. It is found that women who were overweight or obese before pregnancy are at higher risk of adverse pregnancy outcomes except for SGA neonates, while pre-pregnancy underweight is a protective factor for GDM, preeclampsia, cesarean delivery, macrosomia and LGA, but not SGA. Younger mothers are more susceptible to GDM and macrosomia neonates, while older mothers are more prone to preeclampsia. Pre-pregnancy BMI has more influence on various pregnancy outcomes than maternal age. To improve pregnancy outcomes, normal BMI weight as well as relatively young maternal ages are recommended for women in child-bearing age.


2022 ◽  
pp. jech-2021-217754
Author(s):  
Lixin Li ◽  
Yanpeng Wu ◽  
Yao Yang ◽  
Ying Wu ◽  
Yan Zhuang ◽  
...  

BackgroundThe relationship between maternal education and adverse pregnancy outcomes is well documented. However, limited research has investigated maternal educational disparities in adverse pregnancy outcomes in China. This study examined maternal educational inequalities associated with adverse pregnancy outcomes in rural China.MethodsWe conducted a population-based cohort study using participants enrolled in the National Free Preconception Health Examination Project in Yunnan province from 2010 to 2018. The primary outcome was stillbirth, and the secondary outcome was adverse pregnancy outcomes, defined as a composite event of stillbirth, preterm birth or low birth weight. The study was restricted to singleton births at 20–42 weeks’ gestation. Univariate and multivariate log-binomial regression models were performed to estimate crude risk ratios (RRs) and confounding-adjusted RRs (ARRs) for stillbirth and adverse pregnancy outcomes according to maternal education level.ResultsA total of 197 722 singleton births were included in the study. Compared with mid-educated women, low-educated women were at a significantly increased risk of stillbirth (ARR, 1.20; 95% CI, 1.05 to 1.38) and adverse pregnancy outcomes (ARR, 1.11; 95% CI, 1.07 to 1.16). However, the risk of stillbirth (ARR, 1.16; 95% CI, 1.01 to 1.35) was significantly higher for high-educated women compared with mid-educated women.ConclusionCompared with women with medium education level, women with lower education level were more likely to experience adverse pregnancy outcomes, including stillbirth, and women with higher education level were more likely to experience stillbirth.


2021 ◽  
Author(s):  
Ying Tang ◽  
Yan Zeng ◽  
Taizhu Yang ◽  
Pan Yang ◽  
Shan Bao ◽  
...  

Abstract ObjectivesTo investigate twin reversed arterial perfusion (TRAP) sequence for the prediction of TRAP-related adverse pregnancy outcomes at the gestational age of 11-14 weeks. MethodsPregnant women in the first trimester diagnosed with TRAP were recruited at West China Second University Hospital from January 2015 to June 2018. Systematic screening for the pump twin’s crown-rump length (CRL) and acardiac twin’s upper pole-rump length (URL) was conducted using ultrasonic detection. The (CRL-URL)/CRL and URL/CRL ratios were used to assess the pregnancy outcomes for the pump twin. ResultsTwenty-one pregnant women aged 21–39 years with a gestation of 11-14 weeks were recruited. TRAP was diagnosed on average (± standard deviation [SD]) at pregnancy week 13.1 ± 0.18. The pump twins’ mean (± SD) CRL was 6.65 ± 1.1 cm. The incidence of intrauterine death for the pump twins was 19.0% (n=4), the miscarriage rate was 14.3% (n=3), and the live birth rate was 66.7% (n=14). The (CRL-URL)/CRL ratios between the non-survival (intrauterine death and miscarriage) and survival groups significantly differed (0.33 ± 0.08 vs. 0.58 ± 0.08, p < 0.05). Similarly, the URL/CRL ratios between the non-survival and survival groups significantly differed (0.67 ± 0.08 vs. 0.42 ± 0.08, p < 0.05). ConclusionsThe (CRL-URL)/CRL and URL/CRL ratios were valuable indicators for determining pregnancy outcomes of pump twins with TRAP at an early gestational age.


BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e049075
Author(s):  
Dionne V Gootjes ◽  
Anke G Posthumus ◽  
Vincent W V Jaddoe ◽  
Eric A P Steegers

ObjectiveTo study the associations between neighbourhood deprivation and fetal growth, including growth in the first trimester, and adverse pregnancy outcomes.DesignProspective cohort study.SettingThe Netherlands, Rotterdam.Participants8617 live singleton births from the Generation R cohort study.ExpositionLiving in a deprived neighbourhood.Main outcome measuresFetal growth trajectories of head circumference, weight and length.Secondary outcomes measuresSmall-for-gestational age (SGA) and preterm birth (PTB).ResultsNeighbourhood deprivation was not associated with first trimester growth. However, a higher neighbourhood status score (less deprivation) was associated with increased fetal growth in the second and third trimesters (eg, estimated fetal weight; adjusted regression coefficient 0.04, 95% CI 0.02 to 0.06). Less deprivation was also associated with decreased odds of SGA (adjusted OR 0.91, 95% CI 0.86 to 0.97, p=0.01) and PTB (adjusted OR 0.89, 95% CI 0.82 to 0.96, p=0.01).ConclusionsWe found an association between neighbourhood deprivation and fetal growth in the second and third trimester pregnancy, but not with first trimester growth. Less neighbourhood deprivation is associated with lower odds of adverse pregnancy outcomes. The associations remained after adjustment for individual-level risk factors. This supports the hypothesis that living in a deprived neighbourhood acts as an independent risk factor for fetal growth and adverse pregnancy outcomes, above and beyond individual risk factors.


BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e038187
Author(s):  
Yuelin Wu ◽  
Sheng Wan ◽  
Shengyi Gu ◽  
Zhengqian Mou ◽  
Lingling Dong ◽  
...  

ObjectiveTo assess the associations of gestational weight gain (GWG) in early and late pregnancy with subsequent risks of adverse pregnancy outcomes in Chinese women.DesignProspective cohort study.SettingShanghai, China.ParticipantsWe studied 2630 nulliparous singleton pregnant women with complete data on weight gain in early (≤17 weeks of gestation) and late (>17 weeks) pregnancy in the Shanghai Birth Cohort.MethodsGWG was standardised into z-scores by gestational age and categorised as low (z-score <−1), normal (−1 to +1) and high (>1). The adjusted relative risks (aRRs) and 95%CIs were estimated through log-binomial regression models. Interaction effects between GWG and some other adjustment factors were tested, further stratified analyses were performed separately where interaction terms were significant.Outcome measuresAdverse maternal and neonatal outcomes.ResultsIndependent from GWG in late pregnancy, higher GWG in early pregnancy was associated with higher risks of gestational diabetes mellitus (aRR: 1.66; 95% CI: 1.11 to 2.48), caesarean section (aRR: 1.21; 95% CI: 1.05 to 1.39) and prolonged hospitalisation (aRR: 1.56; 95% CI: 1.03 to 2.38). Higher GWG in late pregnancy was independently associated with higher risks of caesarean section (aRR: 1.24; 95% CI: 1.09 to 1.41), large for gestational age (aRR: 2.01; 95% CI: 1.50 to 2.7) and macrosomia (aRR: 1.90; 95% CI: 1.30 to 2.78). In addition, the risk of gestational hypertension increased significantly with increased total GWG (aRR: 1.78; 95% CI: 1.14 to 2.76). The effects of GWG in late pregnancy on maternal and neonatal outcomes were significantly different between the women bearing a female and the women bearing male fetus.ConclusionThe GWG associations with adverse pregnancy outcomes differ at early and late pregnancy, and there may be effect modification by fetal sex in the association of GWG in late pregnancy with some pregnancy outcomes.


2001 ◽  
Vol 35 (6) ◽  
pp. 502-507 ◽  
Author(s):  
Luciana Bertoldi Nucci ◽  
Maria Inês Schmidt ◽  
Bruce Bartholow Duncan ◽  
Sandra Costa Fuchs ◽  
Eni Teresinha Fleck ◽  
...  

INTRODUCTION: Although obesity is well recognized as a current public health problem, its prevalence and impact among pregnant women have been less investigated in Brazil. The objective of the study was to evaluate the impact of pre-obesity and obesity among pregnant women, describing its prevalence and risk factors, and their association with adverse pregnancy outcomes. METHODS: A cohort of 5,564 pregnant women, aged 20 years or more, enrolled at aproximately 20 to 28 weeks of pregnancy, seen in prenatal public clinics of six state capitals in Brazil were followed up, between 1991 and 1995. Prepregnancy weight, age, educational level and parity were obtained from a standard questionnaire. Height was measured in duplicate and the interviewer assigned the skin color. Nutritional status was defined using body mass index (BMI), according to World Health Organization (WHO) criteria. Odds ratios and 95% confidence interval were calculated using logistic regression. RESULTS: Age-adjusted prevalences (and 95% CI) based on prepregnancy weight were: underweight 5.7% (5.1%-6.3%), overweight 19.2% (18.1%-20.3%), and obesity 5.5% (4.9%-6.2%). Obesity was more frequently observed in older black women, with a lower educational level and multiparous. Obese women had higher frequencies of gestational diabetes, macrosomia, hypertensive disorders, and lower risk of microsomia. CONCLUSIONS: Overweight nutritional status (obesity and pre-obesity) was seen in 25% of adult pregnant women and it was associated with increased risk for several adverse pregnancy outcomes, such as gestational diabetes and pre-eclampsia.


2021 ◽  
Author(s):  
Mouctar Sow ◽  
Marie-France Raynault ◽  
Myriam Spiegelaere

Abstract Objective This paper compares the associations between socioeconomic status (SES) and 1) low birth weight (LBW) and 2) preterm birth, in Brussels and Montreal, and discusses hypotheses that may explain the differences between these two regions. Methods This population-based study uses administrative databases from Belgian and Quebec birth records. The analysis is based on 97,844 and 214,620 singleton live births in Brussels and Montreal, respectively. Logistic regression models were developed for each region in order to estimate the relationship between SES (maternal education and income quintile) and pregnancy outcomes. The analyses were performed for all births according to the mother’s origin. Results SES is associated with LBW and preterm birth in both regions. This association varies according to the mother’s birth place; the impact of SES being greater for mothers born in Belgium or Canada than for those born abroad. The main difference between the two regions concerns the magnitude of perinatal inequalities, which is greater in Montreal than in Brussels, whether among the general population, native-born mothers, or immigrant mothers. Conclusion Significant differences in social inequalities in perinatal health are observed between Brussels and Montreal. The different characteristics of low-income and immigrant households between the two contexts help explain these results. In fact, the poor are relatively poorer in Quebec than in Belgium and live in a more unequal context.


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