scholarly journals Development of the Tissue Engineered Medical Products Based on Silk Fibroin from Bombyx mori and Transgenic Silkworm

2009 ◽  
Vol 65 (1) ◽  
pp. P.11-P.13 ◽  
Author(s):  
YASUMOTO NAKAZAWA ◽  
TETSUO ASAKURA
Keyword(s):  
Bombyx Mori ◽  
Silk Fibroin ◽  
Transgenic Silkworm ◽  
Medical Products

Introduction of VEGF or RGD sequences improves revascularization properties of Bombyx mori silk fibroin produced by transgenic silkworm

2015 ◽  
Vol 3 (35) ◽  
pp. 7109-7116 ◽  
Author(s):  
Toshiki Saotome ◽  
Haruki Hayashi ◽  
Ryo Tanaka ◽  
Atsushi Kinugasa ◽  
Shouji Uesugi ◽  
...  
Keyword(s):  
Bombyx Mori ◽  
Silk Fibroin ◽  
Platelet Adhesion ◽  
Transgenic Silkworm ◽  
Silk Fibroins ◽  
Bombyx Mori Silk

Transgenic silk fibroins incorporated the VEGF and RGD were prepared. The VEGF SF showed lower platelet adhesion than the RGD SF and WT SF. An in vivo implantation study supported these in vitro results.

scholarly journals Oxygen Permeability of Silk Fibroin Hydrogels and Their Use as Materials for Contact Lenses: A Purposeful Analysis

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 58
Author(s):  
Traian V. Chirila
Keyword(s):  
Tissue Engineering ◽  
Bombyx Mori ◽  
Silk Fibroin ◽  
Biomedical Applications ◽  
Oxygen Permeability ◽  
Contact Lenses ◽  
The Past ◽  
Fibrous Protein ◽  
Silk Moth ◽  
Bombyx Mori Silk

Fibroin is a fibrous protein that can be conveniently isolated from the silk cocoons produced by the larvae of Bombyx mori silk moth. In its form as a hydrogel, Bombyx mori silk fibroin (BMSF) has been employed in a variety of biomedical applications. When used as substrates for biomaterial-cells constructs in tissue engineering, the oxygen transport characteristics of the BMSF membranes have proved so far to be adequate. However, over the past three decades the BMSF hydrogels have been proposed episodically as materials for the manufacture of contact lenses, an application that depends on substantially elevated oxygen permeability. This review will show that the literature published on the oxygen permeability of BMSF is both limited and controversial. Additionally, there is no evidence that contact lenses made from BMSF have ever reached commercialization. The existing literature is discussed critically, leading to the conclusion that BMSF hydrogels are unsuitable as materials for contact lenses, while also attempting to explain the scarcity of data regarding the oxygen permeability of BMSF. To the author’s knowledge, this review covers all publications related to the topic.

MnO2-capped silk fibroin (SF) nanoparticles with chlorin e6 (Ce6) encapsulation for augmented photo-driven therapy by modulating tumor microenvironment

2021 ◽  
Author(s):  
Lei Zhang ◽  
Ruihao Yang ◽  
Honglian Yu ◽  
Zhigang Xu ◽  
Yuejun Kang ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Bombyx Mori ◽  
Silk Fibroin ◽  
Chlorin E6 ◽  
Fibrous Protein

Silk fibroin (SF), derived from Bombyx mori, is a category of fibrous protein with outstanding potential for being applied in biomedical and biotechnological fields. In spite of many advantageous properties,...

Recombinant silk fibroin incorporated cell-adhesive sequences produced by transgenic silkworm as a possible candidate for use in vascular graft

2014 ◽  
Vol 2 (42) ◽  
pp. 7375-7383 ◽  
Author(s):  
Tetsuo Asakura ◽  
Makoto Isozaki ◽  
Toshiki Saotome ◽  
Ken-ichiro Tatematsu ◽  
Hideki Sezutsu ◽  
...  
Keyword(s):  
Silk Fibroin ◽  
Vascular Graft ◽  
Transgenic Silkworm ◽  
Cell Adhesive ◽  
Silk Fibroins

Transgenic silk fibroins that incorporated the laminin sequence were prepared. The adhesive activities tend to increase in the TG silk fibroins relative to WT silk fibroins.

Immobilization of glucose oxidase on nonwoven fabrics with bombyx mori silk fibroin gel

1992 ◽  
Vol 46 (1) ◽  
pp. 49-53 ◽  
Author(s):  
Tetsuo Asakura ◽  
Motohiro Kitaguchi ◽  
Makoto Demura ◽  
Harutoshi Sakai ◽  
Keiichi Komatsu
Keyword(s):  
Glucose Oxidase ◽  
Bombyx Mori ◽  
Silk Fibroin ◽  
Nonwoven Fabrics ◽  
Bombyx Mori Silk
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