scholarly journals Seroprevalence of IgG and IgM anti-Toxoplasma gondii antibodies and associated risks factors in pregnant women of northern Durango, Mexico

2020 ◽  
Vol 62 (6, Nov-Dic) ◽  
pp. 875
Author(s):  
Rolando Adair Facio-Campos ◽  
Cosme Alvarado-Esquivel ◽  
Edgar Olivas-Calderon

Toxoplasmosis is caused by intracellular parasite Toxoplasma gondii (T. gondii). T. gondii infection in pregnancy can result in serious consequences for the developing fetus or newborn, including spontaneous abortion, hydrocephalus, and even death (1).  The infection could be acquired by ingestion of food (raw or uncooked meat from infected animals), direct contact with cat feces or soil contaminated with oocysts.  In 2012 Caballero-Ortega et al., (2) found an increase in the toxoplasmosis distribution in the north region (35%) finding the highest prevalence in coastal regions (67.5%) of México. There is no data historic available about this seroprevalence, specifically of the “Comarca Lagunera” of Durango State. Moreover, previous study of T. gondii seroprevalence in Durango City showed that 6.1% of pregnant woman of urban areas and 8.2% of rural areas were found positives (3). In 2018, 434 pregnant women who used the Health Services of Durango State in the “Comarca Lagunera Region” were studied with an average age of 22.2 years (± 5.95); we found four (0.92%) IgG and none (0.0%) IgM antibodies anti-T. gondii (Table I). Consumption of dried meat (OR = 16.5; 95% CI 1.7 – 161.48; p= 0.01) and sheep and goat meat (OR = 15.61; 95% CI 1.1 – 224.05; p= 0.043) were associated factors to the infection. Number and different types of pets and cats was not associated with anti-T. gondii antibodies. The “Comarca Lagunera” of Durango being a cattle zone, frequently local meat is consumed in general, representing a possible risk factor. It is particularly interesting since this study’s seroprevalence was 0.91% in a small area of Durango State, differing from the global prevalence in the State.  Probably, this results could be due to Durango State having a geographical diversity, Durango capital is located in a valley, unlike the “Comarca Lagunera” region, which is a semi-desert zone with high environmental temperature (Up to 45°C), that could explain the reduced survival of oocysts which implies a subsequent investigation to this work.

2020 ◽  
Vol 2020 (1) ◽  
pp. 1 ◽  
Author(s):  
Dan-Bogdan Navolan ◽  
Florin Gorun ◽  
Cristian Oancea ◽  
Ioana-Mihaela Ciohat ◽  
Daniel Malița ◽  
...  

(1) Background: Toxoplasma gondii and cytomegalovirus belong to a group of pathogens entities called TORCH agents. TORCH represents an acronym which derives from the name of a series of certain pathogenic agents (Toxoplasma gondii, Other agents, Rubella virus, Cytomegalovirus, Herpes virus). They could cross the placenta barrier and cause serious damage to the fetus if a primary infection occurs in a pregnant woman. Immunized women are relatively protected against a reinfection and the risk of a materno-fetal infection in these categories of pregnant women is considered low. (2) Aim of the study: To analyze changes in the percentage of pregnant women seronegative to Toxoplasma gondii and cytomegalovirus along a period of ten years, from 2008 to 2018. (3) Material and Methods: We studied the changes in percentage of seronegative Toxoplasma gondii and Cytomegalovirus pregnant women along two periods: 2008–2010 and 2015–2018. Only pregnant women with declared medium of provenience and unequivocal results were enrolled in the study. (4) Results: In urban areas, we found an increase in the percentage of pregnant women seronegative to Toxoplasma gondii (RR = 1.488, p < 0.0001), respectively to cytomegalovirus (RR = 1.985, p < 0.0001), from 2008–2010 to 2015–2018. A similar increasing trend was found also in rural areas: Toxoplasma gondii (RR = 1.136, p < 0.0322), respectively cytomegalovirus (RR = 1.088, p < 0.8265) but it did not reach a significant threshold for cytomegalovirus. (5) Conclusion: Our study showed that the percentage of women seronegative to Toxoplasma gondii and cytomegalovirus antibodies increases along a period of ten years, from 2008–2010 to 2015–2018, in both urban and rural areas. Probably, the main cause of this trend is represented by the improvement in hygienic condition and food quality control. These results present an argument for continuing the TORCH screening of pregnant women.


1998 ◽  
Vol 120 (1) ◽  
pp. 87-92 ◽  
Author(s):  
P. A. JENUM ◽  
G. KAPPERUD ◽  
B. STRAY-PEDERSEN ◽  
K. K. MELBY ◽  
A. ESKILD ◽  
...  

During one year from June 1992 serum IgG antibodies to Toxoplasma gondii among 35940 pregnant women were measured in a cross-sectional study conducted in Norway. The overall prevalence was 10·9%. The lowest prevalences were detected in the north (6·7%) and in the inland counties (8·2%). A significantly higher prevalence was detected in the southern counties (13·4%) where a mild, coastal climate prevails. Women with foreign names had a higher prevalence (22·6%) than women with Norwegian names (10·0%). The high prevalence among women living in the capital city (Oslo) as compared to other cities and rural areas (13·2% vs. 10·1% and 10·2% respectively), was explained by the higher proportion of foreign women in Oslo. Prevalence significantly increased with age in women over 34 years old. This increase was only detected among women with Norwegian names. An increase in prevalence according to number of children was detected. Women without children had a prevalence of 8·8% while women with three children or more had a prevalence of 14·9%. Multivariate analyses showed that being seropositive was independently associated with county of residence, age, nationality and number of children.


1998 ◽  
Vol 38 (11) ◽  
pp. 87-95
Author(s):  
R. Fenz ◽  
M. Zessner ◽  
N. Kreuzinger ◽  
H. Kroiss

In Austria approximately 70% of the population is connected to sewerage and to biological waste water treatment plants. Whereas the urban areas are already provided with these facilities to a very high extent, effort is still needed in rural areas to meet the requirements of the Austrian legislation. The way, this task should be solved has provoked much controversy. It is mainly the question, whether centralised or decentralised sewage disposal systems are preferable from the ecological and economical point of view, that became a political issue during the last 5 years. The Institute for Water Quality and Waste Management was asked to elaborate a waste water management concept for the Lainsitz River Basin, a mainly rural area in the north of Austria discharging to the Elbe river. Both ecological and economical aspects should be considered. This paper presents the methodology that was applied and the criteria which were decisive for the selection of the final solution.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mingming Cui ◽  
Xiao-Lin Lu ◽  
Yan-Yu Lyu ◽  
Fang Wang ◽  
Xiao-Lu Xie ◽  
...  

Abstract Background The prevalence of neural tube defects (NTDs) in China declined during 2000–2017 with periconceptional folic acid (FA) supplementation, which is effective in reducing the risk of birth defects. We aimed to assess the knowledge and actual use of FA among Chinese pregnant women and to explore factors associated with FA use before pregnancy. Methods All data were collected in face-to-face interviews during health visits among pregnant women. We collected information about knowledge and use of FA supplements and demographic, socioeconomic, and health status. One maternity and childcare hospital was chosen in each of four cities: Beijing, Huaibei, Kunming, and Haikou. In total, 435 pregnant women were randomly recruited for interviews conducted from June to December 2016. Results A total of 428 pregnant women were included in this survey. Of these, 82.0% (351/428) knew that FA can prevent NTDs, and 75.9% (325/428) knew the correct time to take FA. Overall, 65.9% (282/428) of women knew both that FA can prevent NTDs and the recommended time to take FA before pregnancy. Approximately 95.1% (407/428) of women reported having ever taken FA, only 46.3% (198/428) had begun to take FA supplementation before conception, and 64.5% (109/169) of women from rural areas failed to take FA before pregnancy. Women living in northern China (odds ratio [OR] = 1.81, 95% confidence interval [CI], 1.18–2.77), those with unplanned pregnancy (OR = 1.99, 95% CI 1.30–3.04), and highly educated women (OR = 2.37, 95% CI 1.45–3.88) were more likely to know about FA. Women who were homemakers (OR = 1.94, 95% CI 1.21–3.11) and had unplanned pregnancy (OR = 6.18, 95% CI 4.01–9.53) were less likely to begin taking FA before pregnancy. Conclusions Our survey showed that most pregnant women knew about FA. Although preconception intake of FA can help to reduce NTDs, improving the rate of FA intake before pregnancy is needed in urban areas of China, especially among homemakers and women from rural areas or with unplanned pregnancy. Campaigns are needed to increase awareness about FA and FA use before pregnancy among rural women, homemakers, and those with unplanned pregnancy and lower education levels.


2020 ◽  
Vol 5 (12) ◽  
pp. e002169
Author(s):  
Ngatho Samuel Mugo ◽  
Kyaw Swa Mya ◽  
Camille Raynes-Greenow

IntroductionEarly access to adequate antenatal care (ANC) from skilled providers is crucial for detecting and preventing obstetric complications of pregnancy. We aimed to assess factors associated with the utilisation of the new WHO ANC guidelines including the recommended number, on time initiation and adequate components of ANC contacts in Myanmar.MethodsWe examined data from 2943 mothers aged 15–49 years whose most recent birth occurred in the last 5 years prior to the 2015–2016 Myanmar Demographic and Health Survey. Factors associated with utilisation of the new WHO recommended ANC were explored using multinomial logistic regression and multivariate models. We used marginal standardisation methods to estimate the predicted probabilities of the factors significantly associated with the three measures of ANC.ResultsApproximately 18% of mothers met the new WHO recommended number of eight ANC contacts. About 58% of the mothers received adequate ANC components, and 47% initiated ANC within the first trimester of pregnancy. The predicted model shows that Myanmar could achieve 70% coverage of adequate components of ANC if all women were living in urban areas. Similarly, if ANC was through private health facilities, 63% would achieve adequate components of ANC. Pregnant women from urban areas (adjusted risk ratio (aRR): 4.86, 95% CI 2.44 to 9.68) were more than four times more likely to have adequate ANC components compared with women from rural areas. Pregnant women in the highest wealth quintile were three times more likely to receive eight or more ANC contacts (aRR: 3.20, 95% CI 1.61 to 6.36) relative to mothers from the lowest wealth quintile. On time initiation of the first ANC contact was fourfold for mothers aged 30–39 years relative to adolescent mothers (aRR: 4.07, 95% CI 1.53 to 10.84).ConclusionThe 2016 WHO ANC target is not yet being met by the majority of women in Myanmar. Our results highlight the need to address health access inequity for women who are from lower socioeconomic groups, or are younger, and those living in rural areas.


2019 ◽  
Vol IV (III) ◽  
pp. 71-79
Author(s):  
Adnan Ahmad ◽  
Muhammad Ilyas ◽  
Muhammad Nisar Khan

This study reviews the growth strategies and their effect on the efficiency and productivity of the microfinance sector of Pakistan. The sector needs to have adopted intensive growth strategy instead of extensive strategies of wide expansion in term of physical infrastructure and human resources, which had increased the financial sustainability risks for the credit constrain institutions. The sixdimension model of outreach used in this study also shows that the sector does not achieve the targets set forth for these micro finance institutes with respect to its active borrowers’ outreach. The sector has mainly focused the big cities and urban areas whereas the poverty levels are higher in rural areas. The government has also shown its interest by launching two different types of loan schemes. Among the three different types of institution, the microfinance banks dominate the sector.


Finisterra ◽  
2012 ◽  
Vol 40 (79) ◽  
Author(s):  
Manuel Mendes Araújo

The city of Nampula, located in the Northern hinterland of Mozambique, has always been considered the «capital of the North». Founded with the aim of ensuring military control over the colonial penetration of the hinterland, it is an important crossroads where the litoral-hinterland and centre-North axes intersect. Just like Mozambique’sother urban areas, the city of Nampula underwent considerable demographic growth in the period that followed the independence of the country, including the period of civil war and the peace that ensued from 1992 onwards. This demographic growth was the result of a significant migration inflow originating in the rural areas. As the city’s infrastructure and economic activity was unable to keep apace with this growth, the idea of migrating to the city with the aim of improving the livelihood of the migrant population was nothing but a mirage, which eventually resulted in the proliferation of the informal economy as a means of livelihood. The «city of concrete» still exhibits a series of urban and demographic haracteristics that differ substantially from those of the surrounding urban administrative units.


2019 ◽  
Vol 28 (2) ◽  
pp. 283-290 ◽  
Author(s):  
Alexandre Dias Munhoz ◽  
Monia Andrade Souza ◽  
Sonia Carmen Lopo Costa ◽  
Jéssica de Souza Freitas ◽  
Aísla Nascimento da Silva ◽  
...  

Abstract The aim of this study was to determine the frequency and factors associated with Toxoplasma gondii in naturally infected equids in northeastern Brazil. Serum samples from 569 equids (528 horses, 8 mules and 33 donkeys) were subjected to the indirect fluorescent antibody test. Generalized linear models were used to evaluate associated factors. Among the 569 animals sampled, 118 (30.6%) living in rural areas and 14 (26.42%) in urban areas were seropositive (p>0.05). Seropositive animals were observed on 95% of the farms and in all the municipalities. Donkeys/mules as the host, presence of domestic cats and rats on the farm, ingestion of lagoon water and goat rearing remained in the final model as factors associated with infection. Preventive measures such as avoiding the presence of domestic cats close to rearing areas, pastures and sources of water for the animals should be adopted. The wide-ranging distribution of positive animals also indicated that infection in other domestic animals and in humans, through the contaminated environment, was possible. It should be highlighted that there was the possibility that donkeys and mules would continue to have detectable titers for longer, thus explaining the prevalence found. Further studies are needed to confirm this possibility.


2016 ◽  
Vol 12 (3) ◽  
pp. 243
Author(s):  
Aziz El Aasri ◽  
Alaoui Zakaria ◽  
Khadija El Kharrim ◽  
Driss Belghyti ◽  
Yassine Aqachmar ◽  
...  

Between 2006 and 2014, 439 cases of cutaneous leishmaniasis were recorded in the region of Gharb Chrarda Beni Hssen in the north-west of Morocco. With an annual incidence of 49.1 cases per year and a sex-ratio (M / F) of 0.71. The disease has affected all age groups. The most stricken population is children and young people between the ages of 6 months and 30 years with more than 60.26 % of cases. Therefore, Cutaneous leishmaniasis almost hits the rural and urban areas but with an uneven impact. It is higher in rural areas where they are registered with a percentage of 56.7% of cases in contrast to a percentage of 43.3% in urban areas.


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242595
Author(s):  
Leigh F. Johnson ◽  
Mmamapudi Kubjane ◽  
Jeffrey W. Eaton

Background HIV prevalence data among pregnant women have been critical to estimating HIV trends and geographical patterns of HIV in many African countries. Although antenatal HIV prevalence data are known to be biased representations of HIV prevalence in the general population, mathematical models have made various adjustments to control for known sources of bias, including the effect of HIV on fertility, the age profile of pregnant women and sexual experience. Methods and findings We assessed whether assumptions about antenatal bias affect conclusions about trends and geographical variation in HIV prevalence, using simulated datasets generated by an agent-based model of HIV and fertility in South Africa. Results suggest that even when controlling for age and other previously-considered sources of bias, antenatal bias in South Africa has not been constant over time, and trends in bias differ substantially by age. Differences in the average duration of infection explain much of this variation. We propose an HIV duration-adjusted measure of antenatal bias that is more stable, which yields higher estimates of HIV incidence in recent years and at older ages. Simpler measures of antenatal bias, which are not age-adjusted, yield estimates of HIV prevalence and incidence that are too high in the early stages of the HIV epidemic, and that are less precise. Antenatal bias in South Africa is substantially greater in urban areas than in rural areas. Conclusions Age-standardized approaches to defining antenatal bias are likely to improve precision in model-based estimates, and further recency adjustments increase estimates of HIV incidence in recent years and at older ages. Incompletely adjusting for changing antenatal bias may explain why previous model estimates overstated the early HIV burden in South Africa. New assays to estimate the fraction of HIV-positive pregnant women who are recently infected could play an important role in better estimating antenatal bias.


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