scholarly journals Polymorphism in sequence of permanent tooth emergence in Czech children

2019 ◽  
Vol 27 (2) ◽  
pp. 165-169
Author(s):  
Romana Šindelářová ◽  
Zdeněk Broukal
2021 ◽  
Vol 32 (6) ◽  
pp. 107-114
Author(s):  
Isabela Ribeiro Madalena ◽  
Caio Luiz Bitencourt Reis ◽  
Daniela Silva Barroso de Oliveira ◽  
Giovana Daniela Pecharki ◽  
Paula Cristina Trevilatto ◽  
...  

Abstract The purpose of the study was to investigate the association between single nucleotide polymorphisms (SNPs) in genes encoding estrogen receptors (ESR1 and ESR2, respectively) and delayed tooth emergence (DTE). This cross-sectional study was composed of biological unrelated children of both sexes, age ranging from 11 to 13 years old. DTE was defined when the successor primary tooth was still present in the oral cavity after its exfoliation time or the absence of the permanent tooth emergence into the oral cavity. Children were diagnosed with DTE when they had at least one delayed permanent tooth, according to age of exfoliation of each tooth proposed by The American Dental Association. Genomic DNA from saliva was used to evaluate the SNPs in ESR1 (rs9340799 and rs2234693) and ESR2 (rs1256049 and rs4986938) using Real-Time PCR. Chi-square or Fisher exact tests and Logistic Regression adjusted by age and gender were performed. SNP-SNP interaction was accessed by multifactor dimensionality reduction (MDR) analysis also adjusted by gender and age. The established alpha of this study was 5%. Among 537 included children, 296 (55%) were in the “DTE” group and the 241 (45%) were in the “Control” group. Age and gender were not statistically different among the groups (p>0.05). Genotype distribution of the SNPs rs9340799, rs2234693, rs1256049 and rs4986938 were not associated with DTE (p> 0.05). The models elected by MDR were not statistically significant either. Conclusions: The studied SNPs in ESR1 and ESR2 were not associated with permanent DTE.


2003 ◽  
Vol 31 (6) ◽  
pp. 463-470 ◽  
Author(s):  
Roos Leroy ◽  
Kris Bogaerts ◽  
Emmanuel Lesaffre ◽  
Dominique Declerck

1982 ◽  
Vol 10 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Franklin Garcia-Godoy ◽  
Angel N. Diaz ◽  
Jose M. Valle ◽  
Enrique J. Arana

2001 ◽  
Vol 59 (2) ◽  
pp. 165-178 ◽  
Author(s):  
Krishan Sharma ◽  
Sandeep Mittal

2017 ◽  
Vol 76 (3) ◽  
pp. 220-225 ◽  
Author(s):  
Romana Šindelářová ◽  
Petr Soukup ◽  
Zdeněk Broukal

2021 ◽  
Vol 21 (8) ◽  
pp. 510-518
Author(s):  
Elizabeth Webb ◽  
Lisa Woods ◽  
Carol Stewart ◽  
Peggy Fairbairn Dunlop ◽  
Jenny Tangis ◽  
...  

Introduction Global patterning and timing of permanent tooth emergence is influenced by ethnicity, with no known timings reported for ethnic Melanesian children living in the tropical archipelago of Vanuatu. Aim To determine timings of permanent tooth emergence and sequencing for children who reside in rural Vanuatu. Methods Children aged 4-17 years (n=1026), part of a larger oral health cross-sectional study, were examined recording all permanent teeth present, across four spatially separated islands. Binary logistic modelling established children’s median age of emergence of each permanent tooth for each study area. Results The median emergence of first permanent molars for girls is 4.9-years and 5.3 -years for boys. In all locations, children had all permanent teeth emerge by age 11 years (excluding 3rd molars). Clinically important differences exist for permanent tooth emergence by study area. Discussion Permanent teeth emerge earlier for Ni-Vanuatu children compared to both Melanesian children of Papua New Guinea as well as other ethnicities across Oceanic countries. These results can be used as a set standard for Vanuatu. Early tooth emergence suggests oral health education programmes should target pregnant women with clinical preventive strategies commencing for their children before 5-years of age.


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