Hypopharyngeal Pressure in Brass Musicians

2003 ◽  
Vol 18 (4) ◽  
pp. 153-155
Author(s):  
C Richard Stasney ◽  
Mary Es Beaver ◽  
Margarita Rodriguez

Brass instrument players are exposed to unique health risks due to increased pharyngeal pressures necessary for performance. One such risk is development of laryngoceles, or “blowout” of the larynx. This cross-sectional observational study was performed to determine the pressure required to play different frequencies in a variety of brass instruments. The hypothesis tested was that enharmonic frequencies require the same pharyngeal pressure regardless of the instrument. The brass instruments tested were high-pressure, low-flow instruments (trumpet or French horn) or low-pressure, high-flow instruments (tuba or trombone). We were not able to substantiate Jacobs’ theory that enharmonic frequencies resulted in equal pressures regardless of instrument, but we did elicit some high pressures in the hypopharynx when playing the trumpet or horn at higher frequencies.

2018 ◽  
Vol 11 (10) ◽  
pp. 5565-5586 ◽  
Author(s):  
Michael F. Schibig ◽  
Duane Kitzis ◽  
Pieter P. Tans

Abstract. Long-term monitoring of carbon dioxide (CO2) in the atmosphere is key for a better understanding of the processes involved in the carbon cycle that have a major impact on further climate change. Keeping track of large-scale emissions and removals (sources and sinks) of CO2 requires very accurate measurements. They all have to be calibrated very carefully and have to be traceable to a common scale, the World Meteorological Organization (WMO) CO2 X2007 scale, which is maintained by the National Oceanic and Atmospheric Administration (NOAA) Earth System Research Laboratory (ESRL) in Boulder, CO, USA. The international WMO GAW (Global Atmosphere Watch) program sets as compatibility goals for the required agreement between different methods and laboratories ±0.1 µmol mol−1 for the Northern Hemisphere and ±0.05 µmol mol−1 for the Southern Hemisphere. The reference gas mixtures used to pass down and distribute the scale are stored in high-pressure aluminum cylinders. It is crucial that the standards remain stable during their entire time of use. In this study the tested vertically positioned aluminum cylinders showed similar CO2 enrichment during low-flow conditions (0.3 L min−1), which are similar to flows often used for calibration gases in practical applications. The average CO2 enrichment was 0.090±0.009 µmol mol−1 as the cylinder was emptied from about 150 to 1 bar above atmosphere. However, it is important to note that the enrichment is not linear but follows Langmuir's adsorption–desorption model, where the CO2 enrichment is almost negligible at high pressures but much more pronounced at low pressures. When decanted at a higher rate of 5.0 L min−1 the enrichment becomes 0.22±0.05 µmol mol−1 for the same pressure drop. The higher enrichment is related to thermal diffusion and fractionation effects in the cylinder, which were also dependent on the cylinder's orientation and could even turn negative. However, the low amount of CO2 adsorbed on the cylinder wall and the fact that the main increase happens at low pressure lead to the conclusion that aluminum cylinders are suitable to store ambient CO2-in-dry-air mixtures provided they are not used below 20 bar. In cases where they are used in high-flow experiments that involve significant cylinder temperature changes, special attention has to be paid to possible fractionation effects.


Author(s):  
Takayuki Suzuki ◽  
Takashi Takemura

It is important in development of turbomachinery to predict their performance precisely. Especially the prediction of multistage pump performance is one of the challenging problems because internal phenomena which relate to the performance are complicated. Therefore, in this research, we verified accuracy of Computational Fluid Dynamics (CFD) in predicting performance of a five-stage high-pressure volute pump by comparing predicted values by CFD with measurement data. We tried two methods to predict the pump performance. One is a computation with a complete pump model which includes all five stages and leakage passages. This method can be expected to represent total internal flow phenomena. The other method is totaling up the performance data from separate computations of 1st–2nd stages and series stages. This method is simpler than the former and involves less computational cost. As a result, it was clarified that all the methods could predict pump head at the best efficiency point to some extent, even by steady computation. However, no prediction can predict positive gradient in Q-H curve which was observed in measurement at low flow rate. Except for the unsteady complete pump model computation, efficiency and shaft power could not be predicted precisely. In addition, at high flow rate, unsteady computation of the complete pump model shows the best agreement in head. In the complete pump model computation at high flow rate, the series stage next to the long crossover has larger head because of the influence of it. Therefore, the separated model has difficulty in representing series stages’ performance. In order to predict performance at high flow rate, unsteady computations also including properly the influence of the long crossover properly are necessary. In addition, to predict performance at low flow rate, unsteady computation is necessary.


Author(s):  
Philipp Epple ◽  
Mihai Miclea ◽  
Harald Schmidt ◽  
Antonio Delgado ◽  
Hans Russwurm

High pressure fans for thermal power generation stations, especially biogas plants, usually operate in a spiral casing at high pressures of about p = 12.000–15.000 Pa and low flow rates of around Q = 100–600 m3/s. The motor drive has a constant speed of 3.000 l/min. This corresponds to specific speeds of nq = 3–6 min−1, which is already beyond the conventional range of single stage radial machines. Nowadays these fans for biogas plants usually operate at higher flow rates than specified or are multiple stage radial fans. Therefore a new class of radial impellers has been developed. These single stage impellers have a unique high pressure at a low flow rate operating point. In this work several impellers of this new class have been designed and validated with a commercial Navier-Stokes solver (ANSYS CFX). The design process is described in detail. It is based on a new extended analytical and numerical design method. It is shown that the prescribed unusual operating point can be achieved with single stage radial impellers. An in detail flow analysis is given showing the fundamental flow physics of these impellers.


2005 ◽  
Vol 40 ◽  
pp. 37-42 ◽  
Author(s):  
Gaute Lappegard ◽  
Jack Kohler

AbstractWe have conducted short-term pump experiments with pump pressures exceeding ice overburden to study the seasonality of the subglacial hydraulic system of Engabreen, Norway. Data were collected from load cells installed flush with the ice–bedrock interface and pressure transducers installed in boreholes leading from bedrock tunnels underneath the glacier to the ice–bedrock interface. The water-pressure recordings, seen in relation with the load-cell record, show the existence of hydraulically connected vs unconnected bed areas. Monitored boreholes have been used to inject water at high pressures. Each experiment led to the growth of a high-pressure water cavity whose spatial extent could be inferred from load-cell and pressure transducer records. Post-pump pressures were low after summer pump tests and close to ice-overburden level after winter pump experiments. We conclude that drainage takes place in a fast-flow, low-pressure, channel-based drainage system during summer, and a low-flow, high-pressure, linked-cavity drainage system during winter.


2003 ◽  
Vol 23 (4) ◽  
pp. 423-431 ◽  
Author(s):  
Johannes Vogel ◽  
Christian Hörner ◽  
Christlieb Haller ◽  
Wolfgang Kuschinsky

Vascular endothelial growth factor (VEGF) induces increased vessel permeability and formation of abnormal vessels. To investigate cerebral blood flow (CBF) during local overexpression of VEGF recombinant adenoviruses carrying the human VEGF165 complementary DNA (2.3 to 23 · 108 pfu/mL) were injected stereotactically into the caudate nucleus of anesthetized rats. Saline and adenoviruses carrying the β-galactosidase gene served as controls. Eleven days later (1) size and density of vessels were assessed in hematoxylin–eosin–stained sections, (2) vascular permeability was measured by intravenous Evans blue injections, and (3) local CBF (lCBF) was quantified using the iodo-[14C]antipyrine technique. Dose-dependent increases were found in (1) vessel density and size (only vessels >43 μm could be quantified morphologically), (2) Evans blue extravasation and brain edema formation, and (3) lCBF (up to eightfold). At medium doses, hyperemic areas and smaller areas of decreased lCBF were found. In low flow areas, vascular cross-sectional areas were increased 223-fold and vessel density up to 10-fold. In high flow areas, these parameters were increased 32-fold and up to 15-fold, respectively. Adenovirus mediated VEGF overexpression results in (1) increased vessel size and density, (2) areas of increased and of decreased flow, and (3) more and smaller vessels in high flow than in low flow areas. These results indicate a diverging flow pattern of newly formed vessels.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lauriana Alves Santana ◽  
Suellen Karoline Moreira Bezerra ◽  
Beatriz Mangueira Saraiva-Romanholo ◽  
Wellington Pereira Yamaguti ◽  
Iolanda de Fátima Lopes Calvo Tibério ◽  
...  

AbstractSome clinical situations require the use of oxygen therapy for a few hours without hypoxemia. However, there are no literature reports on the effects of acute oxygen therapy on the nasal mucosa. This study aimed to evaluate the acute effects of cold bubble humidification or dry oxygen on nasal Inflammation, oxidative stress, mucociliary clearance, and nasal symptoms. This is a randomized controlled cross-sectional study in which healthy subjects were randomly allocated into four groups: (1) CA + DRY (n = 8): individuals receiving dry compressed air; (2) OX + DRY (n = 8): individuals receiving dry oxygen therapy; (3) CA + HUMID (n = 7): individuals receiving cold bubbled humidified compressed air; (4) OX + HUMID (n = 8): individuals receiving cold bubbled humidified oxygen therapy. All groups received 3 L per minute (LPM) of the oxygen or compressed air for 1 h and were evaluated: total and differential cells in the nasal lavage fluid (NLF), exhaled nitric oxide (eNO), 8-iso-PGF2α levels, saccharin transit test, nasal symptoms, and humidity of nasal cannula and mucosa. Cold bubble humidification is not able to reduced nasal inflammation, eNO, oxidative stress, mucociliary clearance, and nasal mucosa moisture. However, subjects report improvement of nasal dryness symptoms (P < 0.05). In the conclusion, cold bubble humidification of low flow oxygen therapy via a nasal cannula did not produce any effect on the nasal mucosa and did not attenuate the oxidative stress caused by oxygen. However, it was able to improve nasal symptoms arising from the use of oxygen therapy.


2021 ◽  
Vol 23 (7) ◽  
pp. 4277-4286
Author(s):  
S. V. Chuvikov ◽  
E. A. Berdonosova ◽  
A. Krautsou ◽  
J. V. Kostina ◽  
V. V. Minin ◽  
...  

Pt-Catalyst plays a key role in hydrogen adsorption by Cu-BTC at high pressures.


Author(s):  
Kun Li ◽  
Junjie Wang ◽  
Vladislav A. Blatov ◽  
Yutong Gong ◽  
Naoto Umezawa ◽  
...  

AbstractAlthough tin monoxide (SnO) is an interesting compound due to its p-type conductivity, a widespread application of SnO has been limited by its narrow band gap of 0.7 eV. In this work, we theoretically investigate the structural and electronic properties of several SnO phases under high pressures through employing van der Waals (vdW) functionals. Our calculations reveal that a metastable SnO (β-SnO), which possesses space group P21/c and a wide band gap of 1.9 eV, is more stable than α-SnO at pressures higher than 80 GPa. Moreover, a stable (space group P2/c) and a metastable (space group Pnma) phases of SnO appear at pressures higher than 120 GPa. Energy and topological analyses show that P2/c-SnO has a high possibility to directly transform to β-SnO at around 120 GPa. Our work also reveals that β-SnO is a necessary intermediate state between high-pressure phase Pnma-SnO and low-pressure phase α-SnO for the phase transition path Pnma-SnO →β-SnO → α-SnO. Two phase transition analyses indicate that there is a high possibility to synthesize β-SnO under high-pressure conditions and have it remain stable under normal pressure. Finally, our study reveals that the conductive property of β-SnO can be engineered in a low-pressure range (0–9 GPa) through a semiconductor-to-metal transition, while maintaining transparency in the visible light range.


2021 ◽  
Author(s):  
Florian Caillon ◽  
Katharina Besemer ◽  
Peter Peduzzi ◽  
Jakob Schelker

AbstractFlood events are now recognized as potentially important occasions for the transfer of soil microbes to stream ecosystems. Yet, little is known about these “dynamic pulses of microbial life” for stream bacterial community composition (BCC) and diversity. In this study, we explored the potential alteration of stream BCC by soil inoculation during high flow events in six pre-alpine first order streams and the larger Oberer Seebach. During 1 year, we compared variations of BCC in soil water, stream water and in benthic biofilms at different flow conditions (low to intermediate flows versus high flow). Bacterial diversity was lowest in biofilms, followed by soils and highest in headwater streams and the Oberer Seebach. In headwater streams, bacterial diversity was significantly higher during high flow, as compared to low flow (Shannon diversity: 7.6 versus 7.9 at low versus high flow, respectively, p < 0.001). Approximately 70% of the bacterial operational taxonomic units (OTUs) from streams and stream biofilms were the same as in soil water, while in the latter one third of the OTUs were specific to high flow conditions. These soil high-flow OTUs were also found in streams and biofilms at other times of the year. These results demonstrate the relevance of floods in generating short and reoccurring inoculation events for flowing waters. Moreover, they show that soil microbial inoculation during high flow enhances microbial diversity and shapes fluvial BCC even during low flow. Hence, soil microbial inoculation during floods could act as a previously overlooked driver of microbial diversity in headwater streams.


2020 ◽  
Author(s):  
Kenji Ohta ◽  
Kei Hirose

Abstract Precise determinations of the thermal conductivity of iron alloys at high pressures and temperatures are essential for understanding the thermal history and dynamics of the metallic cores of the Earth. We review relevant high-pressure experiments using a diamond-anvil cell and discuss implications of high core conductivity for its thermal and compositional evolution.


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