Inheritance Pattern of Female Receptivity inDrosophila prolongata

2016 ◽  
Vol 33 (5) ◽  
pp. 455-460 ◽  
Author(s):  
Yurika Hitoshi ◽  
Yukio Ishikawa ◽  
Takashi Matsuo
Neuron ◽  
2014 ◽  
Vol 83 (1) ◽  
pp. 149-163 ◽  
Author(s):  
Chuan Zhou ◽  
Yufeng Pan ◽  
Carmen C. Robinett ◽  
Geoffrey W. Meissner ◽  
Bruce S. Baker

2020 ◽  
Vol 287 (1923) ◽  
pp. 20192765 ◽  
Author(s):  
Tabashir Chowdhury ◽  
Ryan M. Calhoun ◽  
Katrina Bruch ◽  
Amanda J. Moehring

Female mate rejection acts as a major selective force within species, and can serve as a reproductive barrier between species. In spite of its critical role in fitness and reproduction, surprisingly little is known about the genetic or neural basis of variation in female mate choice. Here, we identify fruitless as a gene affecting female receptivity within Drosophila melanogaster , as well as female Drosophila simulans rejection of male D. melanogaster . Of the multiple transcripts this gene produces, by far the most widely studied is the sex-specifically spliced transcript involved in the sex determination pathway. However, we find that female rejection behaviour is affected by a non-sex-specifically spliced fruitless transcript. This is the first implication of fruitless in female behaviour, and the first behavioural role identified for a fruitless non-sex-specifically spliced transcript. We found that this locus does not influence preferences via a single sensory modality, examining courtship song, antennal pheromone perception, or perception of substrate vibrations, and we conclude that fruitless influences mate choice via the integration of multiple signals or through another sensory modality.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Naveed Natanzi ◽  
David Peng ◽  
Eli Ahdoot ◽  
Sandra Ghatan ◽  
Amy Reinstandler ◽  
...  

Xanthoma disseminatum (XD) is a rare normolipemic histiocytic disorder of non-Langerhans cell origin characterized by erythematous to tan/brown papules in flexor surfaces. Considered a generally benign, chronic disease of unknown etiology, XD typically affects the skin, mucous membranes, and less commonly, other organs. To date, there has been no typical or consistent inheritance pattern described, nor has it ever been considered as a component of any known syndrome. We describe, for the first time, two cases of XD in a pair of blind and deaf twin brothers.


Author(s):  
Mark P. Mooney ◽  
H. Losken Wolfgang ◽  
Michael I. Siegel ◽  
Janice F. Lalikos ◽  
Albert Losken ◽  
...  

The lack of an animal model of congenital coronal suture (CS) synostosis has prompted the widespread use of an experimental rabbit model using adhesive Immobilization of the CS. Such postnatal models have helped make significant scientific contributions but may still not fully represent all aspects of the human congenital condition. In the March 1993 issue of The Cleft Palate-Craniofacial Journal we reported a female rabbit born in our laboratory with complete bilateral CS synostosis. This follow-up study presents our attempts to breed this animal and establish a strain of cranlosynostotic rabbits. To date, we have accomplished 10 back- and intercrosses with these animals and have produced a total of 71 live offspring; 10 animals exhibited complete nonsyndromic unilateral (plagiocephalic) or bilateral (brachycephalic) CS synostotic deformities at birth, and 19 animals exhibited partial CS synostosis that showed more than 75% growth retardation across the CS (well below the 95% confidence interval for normals). Results revealed that gestational time and litter size averages were consistent with those reported for the strain, although the average litter size decreased with increased inbreeding. By 1.5 weeks of age the completely synostosed animals already exhibited brachycephalic cranial vaults and midfacial hypoplasia compared to unaffected siblings. Initial pedigree analysis suggested an autosomal dominant inheritance pattern with incomplete penetrance and variable expressivity. The development of such a congenital rabbit model may prove useful In helping to understand the etiopathogenesis of this condition In human populations.


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