Diverse Families of Antimicrobial Peptides Isolated from Skin Secretions of Three Species of East Asian Frogs,Babina daunchina,Babina adenopleura, andRana omeimontis(Ranidae)

2014 ◽  
Vol 31 (7) ◽  
pp. 438-444 ◽  
Author(s):  
Yuhong Hu ◽  
Shiqi Xu ◽  
Yonghong Hu ◽  
Chao Guo ◽  
Hao Meng ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
East Asian ◽  
Diverse Families ◽  
Skin Secretions

Antimicrobial peptides from the skin secretions of the South-East Asian frog Hylarana erythraea (Ranidae)

Peptides ◽  
2010 ◽  
Vol 31 (4) ◽  
pp. 548-554 ◽  
Author(s):  
Nadia Al-Ghaferi ◽  
Jolanta Kolodziejek ◽  
Norbert Nowotny ◽  
Laurent Coquet ◽  
Thierry Jouenne ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
East Asian ◽  
The South ◽  
Skin Secretions

Antimicrobial Peptides from Skin Secretions ofHypsiboas pulchellus(Anura: Hylidae)

2014 ◽  
Vol 77 (4) ◽  
pp. 831-841 ◽  
Author(s):  
Alvaro Siano ◽  
María Verónica Húmpola ◽  
Eliandre de Oliveira ◽  
Fernando Albericio ◽  
Arturo C. Simonetta ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Skin Secretions

Purification and properties of antimicrobial peptides from skin secretions of the Eritrea clawed frog Xenopus clivii (Pipidae)

2011 ◽  
Vol 153 (3) ◽  
pp. 350-354 ◽  
Author(s):  
J. Michael Conlon ◽  
Milena Mechkarska ◽  
Eman Ahmed ◽  
Jérôme Leprince ◽  
Hubert Vaudry ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Purification And Properties ◽  
Skin Secretions ◽  
Clawed Frog

Structure-function relationships in bombinins H, antimicrobial peptides from Bombina skin secretions☆

Peptides ◽  
2000 ◽  
Vol 21 (11) ◽  
pp. 1673-1679 ◽  
Author(s):  
M.Luisa Mangoni ◽  
Nicoletta Grovale ◽  
Alessandra Giorgi ◽  
Giuseppina Mignogna ◽  
Maurizio Simmaco ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Structure Function ◽  
Skin Secretions

scholarly journals Development of Antimicrobial Peptides from Amphibians

Antibiotics ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 772
Author(s):  
Maria Luisa Mangoni ◽  
Bruno Casciaro
Keyword(s):  
Xenopus Laevis ◽  
Antimicrobial Peptides ◽  
Anuran Species ◽  
Skin Secretions

Since the discovery of magainins from the skin secretions of the African toad Xenopus laevis by Michael Zasloff in 1987, an increasing number of antimicrobial peptides (AMPs) has been identified in different anuran species and studied in detail [...]

scholarly journals Development and Challenges of Antimicrobial Peptides for Therapeutic Applications

Antibiotics ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 24 ◽  
Author(s):  
Charles H. Chen ◽  
Timothy K. Lu
Keyword(s):  
Antimicrobial Peptides ◽  
Soil Bacteria ◽  
Bacterial Infections ◽  
Mechanisms Of Action ◽  
The Body ◽  
Antimicrobial Drugs ◽  
Skin Secretions ◽  
Approved Drugs ◽  
Topical Medications ◽  
Fda Approved Drugs

More than 3000 antimicrobial peptides (AMPs) have been discovered, seven of which have been approved by the U.S. Food and Drug Administration (FDA). Now commercialized, these seven peptides have mostly been utilized for topical medications, though some have been injected into the body to treat severe bacterial infections. To understand the translational potential for AMPs, we analyzed FDA-approved drugs in the FDA drug database. We examined their physicochemical properties, secondary structures, and mechanisms of action, and compared them with the peptides in the AMP database. All FDA-approved AMPs were discovered in Gram-positive soil bacteria, and 98% of known AMPs also come from natural sources (skin secretions of frogs and toxins from different species). However, AMPs can have undesirable properties as drugs, including instability and toxicity. Thus, the design and construction of effective AMPs require an understanding of the mechanisms of known peptides and their effects on the human body. This review provides an overview to guide the development of AMPs that can potentially be used as antimicrobial drugs.

Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami

Peptides ◽  
2006 ◽  
Vol 27 (9) ◽  
pp. 2111-2117 ◽  
Author(s):  
J. Michael Conlon ◽  
Nadia Al-Ghaferi ◽  
Bency Abraham ◽  
Hu Jiansheng ◽  
Pascal Cosette ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Diverse Families
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