Transient Soft-Tissue Edema Associated with Implantation of Increasing Doses of rhBMP-2 on an Absorbable Collagen Sponge in an Ectopic Rat Model

2012 ◽  
Vol 94 (20) ◽  
pp. 1845-1852 ◽  
Author(s):  
Hyun W. Bae ◽  
K. Brandon Strenge ◽  
Nomaan Ashraf ◽  
Jeffrey M. Badura ◽  
Steven M. Peckham ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Rat Model ◽  
Collagen Sponge ◽  
Absorbable Collagen Sponge ◽  
Tissue Edema

31. Examination of Transient Soft Tissue Edema Following Implantation of rhBMP-2 on an Absorbable Collagen Sponge in a Rat Ectopic Model

2007 ◽  
Vol 7 (5) ◽  
pp. 15S-16S ◽  
Author(s):  
Hyun W. Bae ◽  
Jeffrey M. Badura ◽  
Steven M. Peckham ◽  
William F. McKay
Keyword(s):  
Soft Tissue ◽  
Collagen Sponge ◽  
Absorbable Collagen Sponge ◽  
Tissue Edema

scholarly journals AB0747 SPECIFIC ULTRASOUND LESIONS IN PSORIATIC ARTHRITIS: PREVALENCE AND CORRELATION WITH DISEASE ACTIVITY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1670.2-1670
Author(s):  
K. Ben Abdelghani ◽  
H. Boussaa ◽  
S. Miladi ◽  
A. Fazaa ◽  
K. Ouenniche ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Soft Tissue ◽  
Disease Activity ◽  
Disease Duration ◽  
Extensor Tendon ◽  
Biological Data ◽  
Dorsal Aspect ◽  
Tissue Edema ◽  
Linear Probe ◽  
The Mean

Background:Psoriatic arthritis (PsA) is a systemic inflammatory disease with articular and extra-articular features. In recent years, Ultrasonography (US) is playing an important role in the diagnosis and monitoring of this disease. Specific US features of PsA have been reported such as enthesitis, peritenon extensor tendon inflammation (PTI) and soft tissue edema.Objectives:The aims of this study were to evaluate the prevalence of these US signs in PsA patients and to determine their association with disease duration and activity.Methods:Patients with peripheral PsA responding to the Classification Criteria for Psoriatic Arthritis (CASPAR) were enrolled. Clinical and biological data were extracted, and then US examination was performed by an experimented rheumatologist blinded to clinical data using a machine type Esaote MyLAb 60 with a linear probe of 6-18 MHz. The following US features were evaluated: PTI at the dorsal aspect of metacarpo-phalangeal (MCP) joints, soft edema at the volar aspect of MCP joints and enthesitis of the digitorum extensor at the dorsal aspect of distal inter-phalangeal (DIP) joints.A p<0.05 was considered statistically significant.Results:We included twenty PsA patients, 8 men and 12 women, with a mean age of 55 ± 11 [33-77] years old. The mean disease duration was of 10±8 [1-34] years. A family history of PsA or psoriasis was reported in 53% of cases.Oral corticosteroids were used in 21% of patients, at a mean daily posology of 7 mg [5-10] of Prednisone equivalent, Methotrexate in 84% of cases at a mean posology of 15 mg [10-20] per week, Sulfasalazine in 10% of cases and a biological DMARD in 32% of cases (Etanercept=4, Infliximab=1, Adalimumab=1).The mean number of tender and swollen joints were respectively of 8 [0-16] and 2 [0-8]. The mean rate of patient global evaluation and visual analogue scale was of 5 [0-9].The mean DAPSA (Disease Activity in PSoriatic Arthritis) score was of 32±27 [4-112].US examination demonstrated that all patients had at least one of the three specific signs that we were looking for. At MCP level, PTI was noted in 11% of joints with Power Doppler (PD) signal in one case and soft tissue edema was noted in 3% of joints.At DIP level, enthesitis of digitorum extensor tendon was noted in 39% of joints. The elementary lesions reported were: enthesophyte in 25%, erosion in 8%, calcification in 5% and thickened or hypoecoic tendon in 4% of joints. However, no PD signal was detected at the enthesis.A positive association was found between DAPSA score and soft tissue edema (p=0.000), but not with PTI (0.668) and enthesitis (0.137). No relation was found between these three lesions and the disease duration.Conclusion:The presence of soft tissue edema, enthesitis and/or PTI on US can be an argument for the diagnosis of PsA. Soft tissue edema is shown to be associated with disease activity.Disclosure of Interests:None declared

scholarly journals Comparison of the bone augmentation ability of absorbable collagen sponge with that of hydroxyapatite/collagen composite

2018 ◽  
Vol 60 (4) ◽  
pp. 514-518 ◽  
Author(s):  
Yasumasa Ozawa ◽  
Tatsuya Kubota ◽  
Takanobu Yamamoto ◽  
Naoya Tsukune ◽  
Ryosuke Koshi ◽  
...  
Keyword(s):  
Collagen Sponge ◽  
Bone Augmentation ◽  
Absorbable Collagen Sponge

Imaging of rare appendicular non-acral soft-tissue chondromas in adults with histopathologic correlation

2017 ◽  
Vol 59 (6) ◽  
pp. 700-708
Author(s):  
Mohamed Ragab Nouh ◽  
Hanan Abd El-Aziz Amr ◽  
Rola H Ali
Keyword(s):  
Soft Tissue ◽  
Signal Intensity ◽  
Tissue Reaction ◽  
High Signal ◽  
Diagnostic Challenge ◽  
Post Contrast ◽  
Intensity Matrix ◽  
Tissue Edema ◽  
Magnetic Resonance Imaging Mri

Background Soft-tissue chondroma (STC) is a rare benign soft tissue tumor that arises primarily in acral extra-skeletal locations. Occasionally, STCs may arise in more proximal non-acral locations, accompanied by non-classic features that label them as indeterminate lesions and pose diagnostic challenge for both radiologists and pathologists alike. Purpose To explicate the potential of diagnostic imaging in the identification and characterization of appendicular non-acral STCs with emphasis on their morphologic magnetic resonance imaging (MRI) enhancement. Material and Methods Our clinical database records were searched for patients with histologically proven primary soft-tissue chondroid lesions over a five-year period. Two musculoskeletal (MSK) trained radiologists evaluated the imaging studies and an MSK pathologist revised the pathological findings. Results The study included six cases of appendicular non-acral STCs (mean age = 40.5 years). The mean size of the tumors was 5.6 cm, with four localized to the knee region, one in the thigh, and one in the sternoclavicular region. All cases showed high signal intensity matrix with low-signal intensity septa on T2-weighted MRI and post-contrast marginal/septal enhancement. The lesions were lobulated and lacked host tissue reaction except for one showing subjacent mild soft-tissue edema. Histologically, the cases lacked overt features of malignancy although one was originally misdiagnosed as chondrosarcoma. Conclusion Non-acral STCs are benign cartilaginous tumors that may pose a diagnostic challenge, both radiologically and pathologically. Collaborative imaging and pathologic workup is needed for better characterization of non-aggression of these lesions, and to avoid diagnostic pitfalls and unnecessary radical resections.

scholarly journals Osteogain® loaded onto an absorbable collagen sponge induces attachment and osteoblast differentiation of ST2 cells in vitro

2016 ◽  
Vol 21 (7) ◽  
pp. 2265-2272 ◽  
Author(s):  
Richard J. Miron ◽  
Masako Fujioka-Kobayashi ◽  
Yufeng Zhang ◽  
Anton Sculean ◽  
Benjamin Pippenger ◽  
...  
Keyword(s):  
Osteoblast Differentiation ◽  
Collagen Sponge ◽  
Absorbable Collagen Sponge
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