Use of Erythrocyte Sedimentation Rate and C-Reactive Protein Level to Diagnose Infection Before Revision Total Knee Arthroplasty

2007 ◽  
Vol 89 (7) ◽  
pp. 1409-1416 ◽  
Author(s):  
Nelson V. Greidanus ◽  
Bassam A. Masri ◽  
Donald S. Garbuz ◽  
S. Darrin Wilson ◽  
M. Gavan McAlinden ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Erythrocyte Sedimentation Rate ◽  
Knee Arthroplasty ◽  
Sedimentation Rate ◽  
Protein Level ◽  
Revision Total Knee Arthroplasty ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Total Knee

scholarly journals Effect of Celecoxib on Surgical Site Inflammation after Total Knee Arthroplasty: A Randomized Controlled Study

2018 ◽  
Vol 27 (5) ◽  
pp. 481-488
Author(s):  
Xun Xu ◽  
Weilin Sang ◽  
Yu Liu ◽  
Libo Zhu ◽  
Haiming Lu ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Sedimentation Rate ◽  
Control Group ◽  
C Reactive Protein ◽  
Tramadol Hydrochloride ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Total Knee ◽  
Experimental Group

Objective: To evaluate the anti-inflammatory effectiveness of celecoxib and its effect on the rehabilitation of joint function after total knee arthroplasty. Methods: 72 patients presented between 2016 and 2017 and were divided into two groups. The experimental group was given 200 mg celecoxib twice daily with tramadol hydrochloride 50 mg twice daily (as required); the control group was given tramadol hydrochloride 50 mg twice daily for 6 weeks from the first day after total knee arthroplasty. Skin temperature around the knee was measured 1 day before surgery, on postoperative days 1 and 3, and at weeks 1, 2, and 6. Inflammatory markers (white blood cell count, C-reactive protein, erythrocyte sedimentation rate, and interleukin-6) were measured preoperatively, on postoperative day 3, and at weeks 1 and 6. Knee Society Score was recorded preoperatively and at postoperative weeks 1, 2, and 6. Results: Except for preoperative skin temperature, the recorded skin temperatures of the experimental group were significantly different compared to those of the control group (p = 0.001, 0.024, 0.030, 0.041, 0.047, respectively). Levels of C-reactive protein were significantly different at the 1st and the 6th week after surgery, differing by 19.3 ± 4.64 mg/L (p < 0.001) and 2.6 ± 0.92 mg/L (p = 0.006). Levels of interleukin-6 showed a significant difference of 6.61 ± 2.36 pg/mL (p = 0.007) at the 1st week after surgery. Until the 6th week after surgery, the erythrocyte sedimentation rate in the experimental group and the control group differed by 17 ± 4.6 mm/h (p = 0.001). Conclusions: Celecoxib has a significant inhibitory effect on postoperative aseptic inflammation.

Serum C-reactive protein and erythrocyte sedimentation rate changes in children after adenotonsillectomy

2021 ◽  
Vol 42 (6) ◽  
pp. 684-691
Author(s):  
Mehrnoosh Mousavi Aghdas ◽  
Nikzad Shahidi ◽  
Shahin Abdollahi Fakhim
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Erythrocyte Sedimentation Rate ◽  
Sedimentation Rate ◽  
Protein Level ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Erythrocyte Sedimentation ◽  
Obstructive Sleep ◽  
Before And After

Background: Sleep-disordered breathing is a common problem in children and is associated with increased cardiovascular morbidity. The circulating level of C-reactive protein, a pro-inflammatory protein, is associated with increased risk for atherosclerosis. The aim of this study was the comparison of C-reactive protein level and erythrocyte sedimentation rate in children with tonsillar hypertrophy before and after adenotonsillectomy. Methods: All patients aged between 4 to 10 years who had underwent adenotonsillectomy due to obstructive sleep apnea were enrolled. Serum C-reactive protein and erythrocyte sedimentation rate were measured before and after adenotonsillectomy. Data were analyzed with SPSS version 19. Results: In this study, 384 patients were enrolled. The average age of the patients was 6.7 years. The C-reactive protein level in 91 patients (23.7 %) was decreased and in 286 patients (74.5%) did not change and in 7 patients (1.8%) it was increased. Decreasing serum C-reactive protein level and erythrocyte sedimentation rate was statistically significant after adenotonsillectomy (P-value < 0.05). Conclusion: Obstructive sleep apnea induces a systemic inflammatory response so frequently associated with an increase in serum C-reactive protein and erythrocyte sedimentation rate that is reversible with surgery and if left untreated may lead to cardiovascular morbidity.

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